U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ire1 serine/threonine-protein kinase/endoribonuclease Ire1 [ Drosophila yakuba ]

Gene ID: 6535731, updated on 24-May-2024

Summary

Go to the top of the page Help
Gene symbol
Ire1
Gene description
serine/threonine-protein kinase/endoribonuclease Ire1
Locus tag
Dyak_GE25112
See related
EnsemblRapid:LOC6535731
Gene type
protein coding
RefSeq status
MODEL
Organism
Drosophila yakuba
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
GE25112; GE25112-PA; GE25112-PB
Orthologs
fruit fly all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Ire1 in Genome Data Viewer
Location:
chromosome: 3R
Exon count:
7
Annotation release Status Assembly Chr Location
102 current Prin_Dyak_Tai18E2_2.1 (GCF_016746365.2) 3R NC_052530.2 (6313658..6328452, complement)
101 previous assembly Prin_Dyak_Tai18E2_2.0 (GCF_016746365.1) 3R NC_052530.1 (6313770..6328564, complement)

Chromosome 3R - NC_052530.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC6535728 Neighboring gene Mitochondrial calcium uptake 3 Neighboring gene venom serine carboxypeptidase Neighboring gene Mitochondrial rRNA methyltransferase 2 Neighboring gene transmembrane protein 256 homolog

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Evolution of genes and genomes on the Drosophila phylogeny. Drosophila 12 Genomes Consortium, et al. Nature, 2007 Nov 8. PMID 17994087

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA endonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables unfolded protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in IRE1-mediated unfolded protein response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mRNA processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of IRE1-TRAF2-ASK1 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
serine/threonine-protein kinase/endoribonuclease IRE1
Names
Dyak\GE25112
Dyak\GE25112-PA
Dyak\GE25112-PB
dyak_GLEANR_8747

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Drosophila yakuba Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Prin_Dyak_Tai18E2_2.1 Primary Assembly

Genomic

  1. NC_052530.2 Reference Prin_Dyak_Tai18E2_2.1 Primary Assembly

    Range
    6313658..6328452 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015191834.2 → XP_015047320.1  serine/threonine-protein kinase/endoribonuclease IRE1

    UniProtKB/TrEMBL
    A0A0R1E0R2, B4PNK3
    Related
    XP_015047320.1, XM_015191834.2
    Conserved Domains (4) summary
    cd09769
    Location:53 → 321
    Luminal_IRE1; The Luminal domain, a dimerization domain, of the Serine/Threonine protein kinase, Inositol-requiring protein 1
    cd10422
    Location:817 → 941
    RNase_Ire1; RNase domain (also known as the kinase extension nuclease domain) of Ire1
    smart00220
    Location:552 → 812
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd13982
    Location:545 → 813
    STKc_IRE1; Catalytic domain of the Serine/Threonine kinase, Inositol-requiring protein 1
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases