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MSH4 mutS homolog 4 [ Canis lupus familiaris (dog) ]

Gene ID: 612681, updated on 5-Mar-2024

Summary

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Official Symbol
MSH4provided by VGNC
Official Full Name
mutS homolog 4provided by VGNC
Primary source
VGNC:VGNC:43440
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See MSH4 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
20
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 6 NC_051810.1 (71334444..71416137, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 6 NC_006588.4 (73406292..73487796, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 6 NC_049227.1 (71269093..71350596, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 6 NC_049266.1 (70834791..70912065, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 6 NC_049747.1 (70780166..70856995, complement)

Chromosome 6 - NC_051810.1Genomic Context describing neighboring genes Neighboring gene stress-70 protein, mitochondrial-like Neighboring gene ankyrin repeat and SOCS box containing 17 Neighboring gene reactive oxygen species modulator 1-like Neighboring gene endoplasmic reticulum membrane-associated RNA degradation protein-like Neighboring gene small nucleolar RNA SNORD45 Neighboring gene small nucleolar RNA SNORD45 Neighboring gene Rab geranylgeranyltransferase subunit beta

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP-dependent DNA damage sensor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mismatched DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in mismatch repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in reciprocal meiotic recombination IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mutS protein homolog 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051810.1 Reference ROS_Cfam_1.0

    Range
    71334444..71416137 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038667674.1 → XP_038523602.1  mutS protein homolog 4 isoform X1

    UniProtKB/TrEMBL
    A0A8P0SQT9
    Conserved Domains (1) summary
    COG0249
    Location:159 → 874
    MutS; DNA mismatch repair ATPase MutS [Replication, recombination and repair]

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049266.1 Alternate UMICH_Zoey_3.1

    Range
    70834791..70912065 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038480383.1 → XP_038336311.1  mutS protein homolog 4 isoform X1

    Conserved Domains (1) summary
    COG0249
    Location:157 → 872
    MutS; DNA mismatch repair ATPase MutS [Replication, recombination and repair]

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049747.1 Alternate UNSW_CanFamBas_1.0

    Range
    70780166..70856995 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038605780.1 → XP_038461708.1  mutS protein homolog 4 isoform X2

  2. XM_038605779.1 → XP_038461707.1  mutS protein homolog 4 isoform X2

  3. XM_038605781.1 → XP_038461709.1  mutS protein homolog 4 isoform X3

  4. XM_038605782.1 → XP_038461710.1  mutS protein homolog 4 isoform X4

RNA

  1. XR_005395914.1 RNA Sequence

  2. XR_005395913.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049227.1 Alternate UU_Cfam_GSD_1.0

    Range
    71269093..71350596 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038541641.1 → XP_038397569.1  mutS protein homolog 4 isoform X5

    UniProtKB/TrEMBL
    A0A8C0KT13

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006588.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    73406292..73487796 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038535504.1 → XP_038391432.1  mutS protein homolog 4 isoform X1

    UniProtKB/TrEMBL
    A0A8P0SQT9
    Conserved Domains (1) summary
    COG0249
    Location:159 → 874
    MutS; DNA mismatch repair ATPase MutS [Replication, recombination and repair]
Nucleotide Protein
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