RCOR1 REST corepressor 1 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: RCOR1provided by VGNC
Official Full Name: REST corepressor 1provided by VGNC
Primary source: VGNC:VGNC:45446
See related: Ensembl:ENSCAFG00845016544
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 8

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	8	NC_051812.1 (70782695..70914590)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	8	NC_006590.4 (70018180..70149933)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	8	NC_049229.1 (70911508..71043165)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	8	NC_049268.1 (70447029..70578641)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	8	NC_049749.1 (70511580..70643208)

Chromosome 8 - NC_051812.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables transcription corepressor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in negative regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of histone deacetylase complex	IEA Inferred from Electronic Annotation more info	PubMed
part_of transcription regulator complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: REST corepressor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051812.1 Reference ROS_Cfam_1.0

Range

70782695..70914590

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038674705.1 → XP_038530633.1 REST corepressor 1 isoform X1

UniProtKB/TrEMBL

A0A8C0LZL0, A0A8C0S4B8, A0A8I3P0D6

Related

ENSCAFP00845023081.1, ENSCAFT00845029365.1

Conserved Domains (3) summary

pfam00249
Location:390 → 433

Myb_DNA-binding; Myb-like DNA-binding domain

pfam01448
Location:110 → 163

ELM2; ELM2 domain

cl21498
Location:199 → 243

SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
XM_038674707.1 → XP_038530635.1 REST corepressor 1 isoform X3

UniProtKB/TrEMBL

A0A8C0K7P9

Conserved Domains (3) summary

pfam00249
Location:281 → 324

Myb_DNA-binding; Myb-like DNA-binding domain

pfam01448
Location:1 → 54

ELM2; ELM2 domain

cl21498
Location:90 → 134

SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
XM_038674706.1 → XP_038530634.1 REST corepressor 1 isoform X2

UniProtKB/TrEMBL

A0A8C0K7P9

Conserved Domains (3) summary

pfam00249
Location:281 → 324

Myb_DNA-binding; Myb-like DNA-binding domain

pfam01448
Location:1 → 54

ELM2; ELM2 domain

cl21498
Location:90 → 134

SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...

Alternate UMICH_Zoey_3.1

Genomic

NC_049268.1 Alternate UMICH_Zoey_3.1

Range

70447029..70578641

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038484277.1 → XP_038340205.1 REST corepressor 1 isoform X1

Conserved Domains (3) summary

pfam00249
Location:390 → 433

Myb_DNA-binding; Myb-like DNA-binding domain

pfam01448
Location:110 → 163

ELM2; ELM2 domain

cl21498
Location:199 → 243

SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
XM_038484279.1 → XP_038340207.1 REST corepressor 1 isoform X3

Conserved Domains (3) summary

pfam00249
Location:281 → 324

Myb_DNA-binding; Myb-like DNA-binding domain

pfam01448
Location:1 → 54

ELM2; ELM2 domain

cl21498
Location:90 → 134

SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
XM_038484278.1 → XP_038340206.1 REST corepressor 1 isoform X2

Conserved Domains (3) summary

pfam00249
Location:281 → 324

Myb_DNA-binding; Myb-like DNA-binding domain

pfam01448
Location:1 → 54

ELM2; ELM2 domain

cl21498
Location:90 → 134

SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049749.1 Alternate UNSW_CanFamBas_1.0

Range

70511580..70643208

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038609870.1 → XP_038465798.1 REST corepressor 1 isoform X1

Conserved Domains (3) summary

pfam00249
Location:390 → 433

Myb_DNA-binding; Myb-like DNA-binding domain

pfam01448
Location:110 → 163

ELM2; ELM2 domain

cl21498
Location:199 → 243

SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
XM_038609872.1 → XP_038465800.1 REST corepressor 1 isoform X3

Conserved Domains (3) summary

pfam00249
Location:281 → 324

Myb_DNA-binding; Myb-like DNA-binding domain

pfam01448
Location:1 → 54

ELM2; ELM2 domain

cl21498
Location:90 → 134

SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
XM_038609871.1 → XP_038465799.1 REST corepressor 1 isoform X2

Conserved Domains (3) summary

pfam00249
Location:281 → 324

Myb_DNA-binding; Myb-like DNA-binding domain

pfam01448
Location:1 → 54

ELM2; ELM2 domain

cl21498
Location:90 → 134

SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049229.1 Alternate UU_Cfam_GSD_1.0

Range

70911508..71043165

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038545794.1 → XP_038401722.1 REST corepressor 1 isoform X1

UniProtKB/TrEMBL

A0A8C0LZL0, A0A8C0S4B8, A0A8I3P0D6

Conserved Domains (3) summary

pfam00249
Location:390 → 433

Myb_DNA-binding; Myb-like DNA-binding domain

pfam01448
Location:110 → 163

ELM2; ELM2 domain

cl21498
Location:199 → 243

SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
XM_038545796.1 → XP_038401724.1 REST corepressor 1 isoform X3

UniProtKB/TrEMBL

A0A8C0K7P9

Conserved Domains (3) summary

pfam00249
Location:281 → 324

Myb_DNA-binding; Myb-like DNA-binding domain

pfam01448
Location:1 → 54

ELM2; ELM2 domain

cl21498
Location:90 → 134

SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
XM_038545795.1 → XP_038401723.1 REST corepressor 1 isoform X2

UniProtKB/TrEMBL

A0A8C0K7P9

Conserved Domains (3) summary

pfam00249
Location:281 → 324

Myb_DNA-binding; Myb-like DNA-binding domain

pfam01448
Location:1 → 54

ELM2; ELM2 domain

cl21498
Location:90 → 134

SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006590.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

70018180..70149933

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038596329.1 → XP_038452257.1 REST corepressor 1 isoform X1

UniProtKB/TrEMBL

A0A8C0LZL0, A0A8P0NJ68

Conserved Domains (3) summary

pfam00249
Location:391 → 434

Myb_DNA-binding; Myb-like DNA-binding domain

pfam01448
Location:111 → 164

ELM2; ELM2 domain

cl21498
Location:200 → 244

SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
XM_038596331.1 → XP_038452259.1 REST corepressor 1 isoform X3

UniProtKB/TrEMBL

A0A8C0K7P9

Conserved Domains (3) summary

pfam00249
Location:281 → 324

Myb_DNA-binding; Myb-like DNA-binding domain

pfam01448
Location:1 → 54

ELM2; ELM2 domain

cl21498
Location:90 → 134

SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
XM_038596330.1 → XP_038452258.1 REST corepressor 1 isoform X2

UniProtKB/TrEMBL

A0A8C0K7P9

Conserved Domains (3) summary

pfam00249
Location:281 → 324

Myb_DNA-binding; Myb-like DNA-binding domain

pfam01448
Location:1 → 54

ELM2; ELM2 domain

cl21498
Location:90 → 134

SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...