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GSDME gasdermin E [ Canis lupus familiaris (dog) ]

Gene ID: 611223, updated on 17-Aug-2024

Summary

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Official Symbol
GSDMEprovided by VGNC
Official Full Name
gasdermin Eprovided by VGNC
Primary source
VGNC:VGNC:39911
See related
Ensembl:ENSCAFG00845010323
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
DFNA5
Orthologs
human mouse all
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Genomic context

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See GSDME in Genome Data Viewer
Location:
chromosome: 14
Exon count:
12
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 14 NC_051818.1 (38147520..38223342, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 14 NC_006596.4 (37761175..37836931, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 14 NC_049235.1 (38295918..38371682, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 14 NC_049274.1 (38261120..38336198, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 14 NC_049755.1 (37953705..38029068, complement)

Chromosome 14 - NC_051818.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene protein associated with LIN7 2, MAGUK p55 family member Neighboring gene uncharacterized LOC111098800 Neighboring gene uncharacterized LOC102153048 Neighboring gene uncharacterized LOC119866098 Neighboring gene oxysterol binding protein like 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in programmed cell death IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
gasdermin-E
Names
DFNA5, deafness associated tumor suppressor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051818.1 Reference ROS_Cfam_1.0

    Range
    38147520..38223342 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038686750.1 → XP_038542678.1  gasdermin-E

    UniProtKB/TrEMBL
    A0A8C0QKZ7, A0A8I3RXU0, A0A8P0S8K2
    Conserved Domains (2) summary
    pfam04598
    Location:1 → 245
    Gasdermin; Gasdermin family
    pfam17708
    Location:280 → 468
    Gasdermin_C; Gasdermin PUB domain

  2. XM_038686749.1 → XP_038542677.1  gasdermin-E

    UniProtKB/TrEMBL
    A0A8C0QKZ7, A0A8I3RXU0, A0A8P0S8K2
    Related
    ENSCAFP00845014164.1, ENSCAFT00845018172.1
    Conserved Domains (2) summary
    pfam04598
    Location:1 → 245
    Gasdermin; Gasdermin family
    pfam17708
    Location:280 → 468
    Gasdermin_C; Gasdermin PUB domain

RNA

  1. XR_005437280.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049274.1 Alternate UMICH_Zoey_3.1

    Range
    38261120..38336198 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038494858.1 → XP_038350786.1  gasdermin-E

  2. XM_038494857.1 → XP_038350785.1  gasdermin-E

RNA

  1. XR_005335780.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049755.1 Alternate UNSW_CanFamBas_1.0

    Range
    37953705..38029068 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038621073.1 → XP_038477001.1  gasdermin-E

  2. XM_038621072.1 → XP_038477000.1  gasdermin-E

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049235.1 Alternate UU_Cfam_GSD_1.0

    Range
    38295918..38371682 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038557134.1 → XP_038413062.1  gasdermin-E

    UniProtKB/TrEMBL
    A0A8C0QKZ7, A0A8I3RXU0, A0A8P0S8K2
    Conserved Domains (2) summary
    pfam04598
    Location:1 → 245
    Gasdermin; Gasdermin family
    pfam17708
    Location:280 → 468
    Gasdermin_C; Gasdermin PUB domain

  2. XM_038557133.1 → XP_038413061.1  gasdermin-E

    UniProtKB/TrEMBL
    A0A8C0QKZ7, A0A8I3RXU0, A0A8P0S8K2
    Conserved Domains (2) summary
    pfam04598
    Location:1 → 245
    Gasdermin; Gasdermin family
    pfam17708
    Location:280 → 468
    Gasdermin_C; Gasdermin PUB domain

RNA

  1. XR_005369540.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006596.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    37761175..37836931 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_848863.6 → XP_853956.2  gasdermin-E

    UniProtKB/TrEMBL
    A0A8C0QKZ7, A0A8I3RXU0, A0A8P0S8K2
    Conserved Domains (2) summary
    pfam04598
    Location:1 → 245
    Gasdermin; Gasdermin family
    pfam17708
    Location:280 → 468
    Gasdermin_C; Gasdermin PUB domain

  2. XM_038436132.1 → XP_038292060.1  gasdermin-E

    UniProtKB/TrEMBL
    A0A8C0QKZ7, A0A8I3RXU0, A0A8P0S8K2
    Conserved Domains (2) summary
    pfam04598
    Location:1 → 245
    Gasdermin; Gasdermin family
    pfam17708
    Location:280 → 468
    Gasdermin_C; Gasdermin PUB domain

RNA

  1. XR_002633013.2 RNA Sequence

Nucleotide Protein
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