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DOCK6 dedicator of cytokinesis 6 [ Canis lupus familiaris (dog) ]

Gene ID: 611163, updated on 17-Aug-2024

Summary

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Official Symbol
DOCK6provided by VGNC
Official Full Name
dedicator of cytokinesis 6provided by VGNC
Primary source
VGNC:VGNC:40050
See related
Ensembl:ENSCAFG00845020181
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See DOCK6 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
51
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 20 NC_051824.1 (50545683..50587769)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 20 NC_006602.4 (49898472..49940350)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 20 NC_049241.1 (50425668..50467527)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 20 NC_049280.1 (49756044..49797955)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 20 NC_049761.1 (50182747..50224812)

Chromosome 20 - NC_051824.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111091378 Neighboring gene tetraspanin 16 Neighboring gene angiopoietin like 8 Neighboring gene KN motif and ankyrin repeat domains 2 Neighboring gene uncharacterized LOC119864741 Neighboring gene uncharacterized LOC111091379 Neighboring gene SPC24 component of NDC80 kinetochore complex

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in small GTPase-mediated signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dedicator of cytokinesis protein 6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051824.1 Reference ROS_Cfam_1.0

    Range
    50545683..50587769
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038428576.1 → XP_038284504.1  dedicator of cytokinesis protein 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0YZM4, A0A8I3P884, A0A8I3PJK1
    Related
    ENSCAFP00845028071.1, ENSCAFT00845035877.1
    Conserved Domains (3) summary
    cd08696
    Location:548 → 725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48 → 157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:1659 → 2081
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins

  2. XM_038428579.1 → XP_038284507.1  dedicator of cytokinesis protein 6 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QUU0, A0A8C0YZS5
    Related
    ENSCAFP00845027853.1, ENSCAFT00845035605.1
    Conserved Domains (3) summary
    cd08696
    Location:548 → 725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48 → 157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:1628 → 2050
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins

  3. XM_038428580.1 → XP_038284508.1  dedicator of cytokinesis protein 6 isoform X4

    UniProtKB/TrEMBL
    A0A8C0QUU0, A0A8C0SSW9, A0A8I3PAE3
    Related
    ENSCAFP00845028879.1, ENSCAFT00845036883.1
    Conserved Domains (3) summary
    cd08696
    Location:548 → 725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48 → 157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:1624 → 2046
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins

  4. XM_038428581.1 → XP_038284509.1  dedicator of cytokinesis protein 6 isoform X5

    UniProtKB/TrEMBL
    A0A8C0QUU0, A0A8C0STM4, A0A8I3PC91
    Related
    ENSCAFP00845029273.1, ENSCAFT00845037369.1
    Conserved Domains (3) summary
    cd08696
    Location:548 → 725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48 → 157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:1593 → 2015
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins

  5. XM_038428582.1 → XP_038284510.1  dedicator of cytokinesis protein 6 isoform X6

    UniProtKB/TrEMBL
    A0A8I3P0W4, A0A8P0SLT1
    Conserved Domains (3) summary
    cd08696
    Location:548 → 725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48 → 157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:1659 → 1854
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins

  6. XM_038428583.1 → XP_038284511.1  dedicator of cytokinesis protein 6 isoform X7

    Conserved Domains (2) summary
    cd08696
    Location:548 → 725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48 → 157
    DUF3398; Domain of unknown function (DUF3398)

  7. XM_038428577.1 → XP_038284505.1  dedicator of cytokinesis protein 6 isoform X2

    UniProtKB/TrEMBL
    A0A8C0JTB3
    Conserved Domains (3) summary
    cd08696
    Location:535 → 712
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:35 → 144
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:1646 → 2068
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049280.1 Alternate UMICH_Zoey_3.1

    Range
    49756044..49797955
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038504216.1 → XP_038360144.1  dedicator of cytokinesis protein 6 isoform X1

    Conserved Domains (3) summary
    cd08696
    Location:548 → 725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48 → 157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:1659 → 2081
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins

  2. XM_038504218.1 → XP_038360146.1  dedicator of cytokinesis protein 6 isoform X3

    Conserved Domains (3) summary
    cd08696
    Location:548 → 725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48 → 157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:1628 → 2050
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins

  3. XM_038504219.1 → XP_038360147.1  dedicator of cytokinesis protein 6 isoform X4

    Conserved Domains (3) summary
    cd08696
    Location:548 → 725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48 → 157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:1624 → 2046
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins

  4. XM_038504220.1 → XP_038360148.1  dedicator of cytokinesis protein 6 isoform X5

    Conserved Domains (3) summary
    cd08696
    Location:548 → 725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48 → 157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:1593 → 2015
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins

  5. XM_038504221.1 → XP_038360149.1  dedicator of cytokinesis protein 6 isoform X6

    Conserved Domains (3) summary
    cd08696
    Location:548 → 725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48 → 157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:1659 → 1854
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins

  6. XM_038504222.1 → XP_038360150.1  dedicator of cytokinesis protein 6 isoform X7

    Conserved Domains (2) summary
    cd08696
    Location:548 → 725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48 → 157
    DUF3398; Domain of unknown function (DUF3398)

  7. XM_038504217.1 → XP_038360145.1  dedicator of cytokinesis protein 6 isoform X2

    Conserved Domains (3) summary
    cd08696
    Location:535 → 712
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:35 → 144
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:1646 → 2068
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049761.1 Alternate UNSW_CanFamBas_1.0

    Range
    50182747..50224812
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038631393.1 → XP_038487321.1  dedicator of cytokinesis protein 6 isoform X1

  2. XM_038631395.1 → XP_038487323.1  dedicator of cytokinesis protein 6 isoform X3

  3. XM_038631396.1 → XP_038487324.1  dedicator of cytokinesis protein 6 isoform X4

  4. XM_038631397.1 → XP_038487325.1  dedicator of cytokinesis protein 6 isoform X5

  5. XM_038631398.1 → XP_038487326.1  dedicator of cytokinesis protein 6 isoform X6

  6. XM_038631399.1 → XP_038487327.1  dedicator of cytokinesis protein 6 isoform X7

  7. XM_038631394.1 → XP_038487322.1  dedicator of cytokinesis protein 6 isoform X2

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049241.1 Alternate UU_Cfam_GSD_1.0

    Range
    50425668..50467527
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038567244.1 → XP_038423172.1  dedicator of cytokinesis protein 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0YZM4, A0A8I3P884, A0A8I3PJK1
    Conserved Domains (3) summary
    cd08696
    Location:548 → 725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48 → 157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:1659 → 2081
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins

  2. XM_038567246.1 → XP_038423174.1  dedicator of cytokinesis protein 6 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QUU0, A0A8C0YZS5
    Conserved Domains (3) summary
    cd08696
    Location:548 → 725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48 → 157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:1628 → 2050
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins

  3. XM_038567247.1 → XP_038423175.1  dedicator of cytokinesis protein 6 isoform X4

    UniProtKB/TrEMBL
    A0A8C0QUU0, A0A8C0SSW9, A0A8I3PAE3
    Conserved Domains (3) summary
    cd08696
    Location:548 → 725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48 → 157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:1624 → 2046
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins

  4. XM_038567248.1 → XP_038423176.1  dedicator of cytokinesis protein 6 isoform X6

    UniProtKB/TrEMBL
    A0A8I3P0W4, A0A8P0SLT1
    Conserved Domains (3) summary
    cd08696
    Location:548 → 725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48 → 157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:1659 → 1854
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins

  5. XM_038567249.1 → XP_038423177.1  dedicator of cytokinesis protein 6 isoform X7

    Conserved Domains (2) summary
    cd08696
    Location:548 → 725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48 → 157
    DUF3398; Domain of unknown function (DUF3398)

  6. XM_038567245.1 → XP_038423173.1  dedicator of cytokinesis protein 6 isoform X2

    UniProtKB/TrEMBL
    A0A8C0JTB3
    Conserved Domains (3) summary
    cd08696
    Location:535 → 712
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:35 → 144
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:1646 → 2068
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    49898472..49940350
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038455415.1 → XP_038311343.1  dedicator of cytokinesis protein 6 isoform X1

    UniProtKB/TrEMBL
    A0A8P0SQY5, A0A8P0TNG0
    Conserved Domains (3) summary
    cd08696
    Location:548 → 725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48 → 157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:1659 → 2081
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins

  2. XM_038455416.1 → XP_038311344.1  dedicator of cytokinesis protein 6 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QUU0, A0A8C0YZS5
    Conserved Domains (3) summary
    cd08696
    Location:548 → 725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48 → 157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:1628 → 2050
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins

  3. XM_038455417.1 → XP_038311345.1  dedicator of cytokinesis protein 6 isoform X4

    UniProtKB/TrEMBL
    A0A8C0QUU0, A0A8P0SXT6
    Conserved Domains (3) summary
    cd08696
    Location:548 → 725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48 → 157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:1624 → 2046
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins

  4. XM_038455418.1 → XP_038311346.1  dedicator of cytokinesis protein 6 isoform X5

    UniProtKB/TrEMBL
    A0A8C0QUU0, A0A8C0STM4, A0A8I3PC91
    Conserved Domains (3) summary
    cd08696
    Location:548 → 725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48 → 157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:1593 → 2015
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins

  5. XM_038455419.1 → XP_038311347.1  dedicator of cytokinesis protein 6 isoform X6

    UniProtKB/TrEMBL
    A0A8I3P0W4, A0A8P0SLT1
    Conserved Domains (3) summary
    cd08696
    Location:548 → 725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48 → 157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:1659 → 1854
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins

  6. XM_038455420.1 → XP_038311348.1  dedicator of cytokinesis protein 6 isoform X7

    Conserved Domains (2) summary
    cd08696
    Location:548 → 725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48 → 157
    DUF3398; Domain of unknown function (DUF3398)

  7. XM_005632867.4 → XP_005632924.2  dedicator of cytokinesis protein 6 isoform X2

    UniProtKB/TrEMBL
    A0A8C0JTB3
    Conserved Domains (3) summary
    cd08696
    Location:535 → 712
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:35 → 144
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:1646 → 2068
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins
Nucleotide Protein
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