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DOCK6 dedicator of cytokinesis 6 [ Canis lupus familiaris (dog) ]

Gene ID: 611163, updated on 17-Aug-2024

Summary

Official Symbol
DOCK6provided by VGNC
Official Full Name
dedicator of cytokinesis 6provided by VGNC
Primary source
VGNC:VGNC:40050
See related
Ensembl:ENSCAFG00845020181
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

See DOCK6 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
51
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 20 NC_051824.1 (50545683..50587769)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 20 NC_006602.4 (49898472..49940350)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 20 NC_049241.1 (50425668..50467527)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 20 NC_049280.1 (49756044..49797955)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 20 NC_049761.1 (50182747..50224812)

Chromosome 20 - NC_051824.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111091378 Neighboring gene tetraspanin 16 Neighboring gene angiopoietin like 8 Neighboring gene KN motif and ankyrin repeat domains 2 Neighboring gene uncharacterized LOC119864741 Neighboring gene uncharacterized LOC111091379 Neighboring gene SPC24 component of NDC80 kinetochore complex

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in small GTPase-mediated signal transduction IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
dedicator of cytokinesis protein 6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051824.1 Reference ROS_Cfam_1.0

    Range
    50545683..50587769
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038428576.1XP_038284504.1  dedicator of cytokinesis protein 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0YZM4, A0A8I3P884, A0A8I3PJK1
    Related
    ENSCAFP00845028071.1, ENSCAFT00845035877.1
    Conserved Domains (3) summary
    cd08696
    Location:548725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:16592081
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins
  2. XM_038428579.1XP_038284507.1  dedicator of cytokinesis protein 6 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QUU0, A0A8C0YZS5
    Related
    ENSCAFP00845027853.1, ENSCAFT00845035605.1
    Conserved Domains (3) summary
    cd08696
    Location:548725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:16282050
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins
  3. XM_038428580.1XP_038284508.1  dedicator of cytokinesis protein 6 isoform X4

    UniProtKB/TrEMBL
    A0A8C0QUU0, A0A8C0SSW9, A0A8I3PAE3
    Related
    ENSCAFP00845028879.1, ENSCAFT00845036883.1
    Conserved Domains (3) summary
    cd08696
    Location:548725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:16242046
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins
  4. XM_038428581.1XP_038284509.1  dedicator of cytokinesis protein 6 isoform X5

    UniProtKB/TrEMBL
    A0A8C0QUU0, A0A8C0STM4, A0A8I3PC91
    Related
    ENSCAFP00845029273.1, ENSCAFT00845037369.1
    Conserved Domains (3) summary
    cd08696
    Location:548725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:15932015
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins
  5. XM_038428582.1XP_038284510.1  dedicator of cytokinesis protein 6 isoform X6

    UniProtKB/TrEMBL
    A0A8I3P0W4, A0A8P0SLT1
    Conserved Domains (3) summary
    cd08696
    Location:548725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:16591854
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins
  6. XM_038428583.1XP_038284511.1  dedicator of cytokinesis protein 6 isoform X7

    Conserved Domains (2) summary
    cd08696
    Location:548725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48157
    DUF3398; Domain of unknown function (DUF3398)
  7. XM_038428577.1XP_038284505.1  dedicator of cytokinesis protein 6 isoform X2

    UniProtKB/TrEMBL
    A0A8C0JTB3
    Conserved Domains (3) summary
    cd08696
    Location:535712
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:35144
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:16462068
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049280.1 Alternate UMICH_Zoey_3.1

    Range
    49756044..49797955
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038504216.1XP_038360144.1  dedicator of cytokinesis protein 6 isoform X1

    Conserved Domains (3) summary
    cd08696
    Location:548725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:16592081
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins
  2. XM_038504218.1XP_038360146.1  dedicator of cytokinesis protein 6 isoform X3

    Conserved Domains (3) summary
    cd08696
    Location:548725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:16282050
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins
  3. XM_038504219.1XP_038360147.1  dedicator of cytokinesis protein 6 isoform X4

    Conserved Domains (3) summary
    cd08696
    Location:548725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:16242046
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins
  4. XM_038504220.1XP_038360148.1  dedicator of cytokinesis protein 6 isoform X5

    Conserved Domains (3) summary
    cd08696
    Location:548725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:15932015
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins
  5. XM_038504221.1XP_038360149.1  dedicator of cytokinesis protein 6 isoform X6

    Conserved Domains (3) summary
    cd08696
    Location:548725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:16591854
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins
  6. XM_038504222.1XP_038360150.1  dedicator of cytokinesis protein 6 isoform X7

    Conserved Domains (2) summary
    cd08696
    Location:548725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48157
    DUF3398; Domain of unknown function (DUF3398)
  7. XM_038504217.1XP_038360145.1  dedicator of cytokinesis protein 6 isoform X2

    Conserved Domains (3) summary
    cd08696
    Location:535712
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:35144
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:16462068
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049761.1 Alternate UNSW_CanFamBas_1.0

    Range
    50182747..50224812
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038631393.1XP_038487321.1  dedicator of cytokinesis protein 6 isoform X1

  2. XM_038631395.1XP_038487323.1  dedicator of cytokinesis protein 6 isoform X3

  3. XM_038631396.1XP_038487324.1  dedicator of cytokinesis protein 6 isoform X4

  4. XM_038631397.1XP_038487325.1  dedicator of cytokinesis protein 6 isoform X5

  5. XM_038631398.1XP_038487326.1  dedicator of cytokinesis protein 6 isoform X6

  6. XM_038631399.1XP_038487327.1  dedicator of cytokinesis protein 6 isoform X7

  7. XM_038631394.1XP_038487322.1  dedicator of cytokinesis protein 6 isoform X2

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049241.1 Alternate UU_Cfam_GSD_1.0

    Range
    50425668..50467527
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038567244.1XP_038423172.1  dedicator of cytokinesis protein 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0YZM4, A0A8I3P884, A0A8I3PJK1
    Conserved Domains (3) summary
    cd08696
    Location:548725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:16592081
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins
  2. XM_038567246.1XP_038423174.1  dedicator of cytokinesis protein 6 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QUU0, A0A8C0YZS5
    Conserved Domains (3) summary
    cd08696
    Location:548725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:16282050
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins
  3. XM_038567247.1XP_038423175.1  dedicator of cytokinesis protein 6 isoform X4

    UniProtKB/TrEMBL
    A0A8C0QUU0, A0A8C0SSW9, A0A8I3PAE3
    Conserved Domains (3) summary
    cd08696
    Location:548725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:16242046
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins
  4. XM_038567248.1XP_038423176.1  dedicator of cytokinesis protein 6 isoform X6

    UniProtKB/TrEMBL
    A0A8I3P0W4, A0A8P0SLT1
    Conserved Domains (3) summary
    cd08696
    Location:548725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:16591854
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins
  5. XM_038567249.1XP_038423177.1  dedicator of cytokinesis protein 6 isoform X7

    Conserved Domains (2) summary
    cd08696
    Location:548725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48157
    DUF3398; Domain of unknown function (DUF3398)
  6. XM_038567245.1XP_038423173.1  dedicator of cytokinesis protein 6 isoform X2

    UniProtKB/TrEMBL
    A0A8C0JTB3
    Conserved Domains (3) summary
    cd08696
    Location:535712
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:35144
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:16462068
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    49898472..49940350
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038455415.1XP_038311343.1  dedicator of cytokinesis protein 6 isoform X1

    UniProtKB/TrEMBL
    A0A8P0SQY5, A0A8P0TNG0
    Conserved Domains (3) summary
    cd08696
    Location:548725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:16592081
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins
  2. XM_038455416.1XP_038311344.1  dedicator of cytokinesis protein 6 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QUU0, A0A8C0YZS5
    Conserved Domains (3) summary
    cd08696
    Location:548725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:16282050
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins
  3. XM_038455417.1XP_038311345.1  dedicator of cytokinesis protein 6 isoform X4

    UniProtKB/TrEMBL
    A0A8C0QUU0, A0A8P0SXT6
    Conserved Domains (3) summary
    cd08696
    Location:548725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:16242046
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins
  4. XM_038455418.1XP_038311346.1  dedicator of cytokinesis protein 6 isoform X5

    UniProtKB/TrEMBL
    A0A8C0QUU0, A0A8C0STM4, A0A8I3PC91
    Conserved Domains (3) summary
    cd08696
    Location:548725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:15932015
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins
  5. XM_038455419.1XP_038311347.1  dedicator of cytokinesis protein 6 isoform X6

    UniProtKB/TrEMBL
    A0A8I3P0W4, A0A8P0SLT1
    Conserved Domains (3) summary
    cd08696
    Location:548725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48157
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:16591854
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins
  6. XM_038455420.1XP_038311348.1  dedicator of cytokinesis protein 6 isoform X7

    Conserved Domains (2) summary
    cd08696
    Location:548725
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:48157
    DUF3398; Domain of unknown function (DUF3398)
  7. XM_005632867.4XP_005632924.2  dedicator of cytokinesis protein 6 isoform X2

    UniProtKB/TrEMBL
    A0A8C0JTB3
    Conserved Domains (3) summary
    cd08696
    Location:535712
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:35144
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:16462068
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins