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Dock6 dedicator of cytokinesis 6 [ Mus musculus (house mouse) ]

Gene ID: 319899, updated on 12-Aug-2019

Summary

Official Symbol
Dock6provided by MGI
Official Full Name
dedicator of cytokinesis 6provided by MGI
Primary source
MGI:MGI:1914789
See related
Ensembl:ENSMUSG00000032198
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA1395; 2410095B20Rik; 4931431C02Rik; C330023D02Rik
Expression
Ubiquitous expression in lung adult (RPKM 44.6), ovary adult (RPKM 27.5) and 26 other tissues See more
Orthologs

Genomic context

See Dock6 in Genome Data Viewer
Location:
9; 9 A3
Exon count:
50
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (21800180..21852718, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (21604624..21657079, complement)

Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae) Neighboring gene KN motif and ankyrin repeat domains 2 Neighboring gene predicted gene, 39305 Neighboring gene microRNA 7083 Neighboring gene angiopoietin-like 8 Neighboring gene RAB3D, member RAS oncogene family Neighboring gene transmembrane protein 205 Neighboring gene coiled-coil domain containing 159

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
small GTPase mediated signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
dedicator of cytokinesis protein 6

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177030.3NP_796004.2  dedicator of cytokinesis protein 6

    Status: VALIDATED

    Source sequence(s)
    AC161371, AC166992, AK049320, BC043042, BU055715, BU701914, BU705495, CB522146, CJ099751, CN535526
    Consensus CDS
    CCDS40555.1
    UniProtKB/Swiss-Prot
    Q8VDR9
    UniProtKB/TrEMBL
    A0A1L1SQR4
    Related
    ENSMUSP00000149156.1, ENSMUST00000217336.1
    Conserved Domains (3) summary
    cd08696
    Location:545722
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:65155
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:16562078
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000075.6 Reference GRCm38.p6 C57BL/6J

    Range
    21800180..21852718 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011242554.3XP_011240856.1  dedicator of cytokinesis protein 6 isoform X5

    See identical proteins and their annotated locations for XP_011240856.1

    UniProtKB/Swiss-Prot
    Q8VDR9
    UniProtKB/TrEMBL
    E9QPN7
    Related
    ENSMUSP00000034728.8, ENSMUST00000034728.8
    Conserved Domains (3) summary
    cd08696
    Location:545722
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:65155
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:16252047
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins
  2. XM_011242553.2XP_011240855.1  dedicator of cytokinesis protein 6 isoform X3

    Conserved Domains (3) summary
    cd08696
    Location:545722
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:65155
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:16212043
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins
  3. XM_011242552.2XP_011240854.1  dedicator of cytokinesis protein 6 isoform X2

    Conserved Domains (3) summary
    cd08696
    Location:545722
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:65155
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:16252047
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins
  4. XM_017313426.2XP_017168915.1  dedicator of cytokinesis protein 6 isoform X1

  5. XM_006510422.3XP_006510485.1  dedicator of cytokinesis protein 6 isoform X4

    Conserved Domains (3) summary
    cd08696
    Location:453630
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:1363
    DUF3398; Domain of unknown function (DUF3398)
    cl06123
    Location:15641986
    DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins
  6. XM_030244416.1XP_030100276.1  dedicator of cytokinesis protein 6 isoform X9

  7. XM_017313427.2XP_017168916.1  dedicator of cytokinesis protein 6 isoform X6

  8. XM_006510423.4XP_006510486.1  dedicator of cytokinesis protein 6 isoform X7

    Conserved Domains (2) summary
    cd08696
    Location:545722
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:65155
    DUF3398; Domain of unknown function (DUF3398)
  9. XM_011242555.3XP_011240857.1  dedicator of cytokinesis protein 6 isoform X8

    Conserved Domains (2) summary
    cd08696
    Location:545722
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    pfam11878
    Location:65155
    DUF3398; Domain of unknown function (DUF3398)

RNA

  1. XR_003947928.1 RNA Sequence

  2. XR_001778931.2 RNA Sequence

  3. XR_003947929.1 RNA Sequence

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