CXCL10 C-X-C motif chemokine ligand 10 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: CXCL10provided by VGNC
Official Full Name: C-X-C motif chemokine ligand 10provided by VGNC
Primary source: VGNC:VGNC:100213
See related: Ensembl:ENSMMUG00000020903
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human all
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Genomic context

Location:: chromosome: 5

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	5	NC_041758.1 (57698478..57699998)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	5	NC_027897.1 (58528129..58529649)

Chromosome 5 - NC_041758.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

G33388 (e-PCR)
- UniSTS:50310

D4S3268 (e-PCR)
- UniSTS:4584

STS-X02530 (e-PCR)
- UniSTS:38645

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables CXCR chemokine receptor binding	IEA Inferred from Electronic Annotation more info	PubMed
enables chemokine activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in antimicrobial humoral immune response mediated by antimicrobial peptide	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cellular response to lipopolysaccharide	IEA Inferred from Electronic Annotation more info	PubMed
involved_in chemokine-mediated signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in inflammatory response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in neutrophil chemotaxis	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: C-X-C motif chemokine 10

Names: 10 kDa interferon gamma-induced protein; 10 kDa interferon-gamma-inducible protein CXCL10; IP-10; gamma-IP10; small inducible cytokine B10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001032892.1 → NP_001028064.1 C-X-C motif chemokine 10 precursor

See identical proteins and their annotated locations for NP_001028064.1

Status: PROVISIONAL

Source sequence(s)

AY044446

UniProtKB/Swiss-Prot

Q8MIZ1

Related

ENSMMUP00000027500.1, ENSMMUT00000029391.3

Conserved Domains (1) summary

cd00273
Location:27 → 91

Chemokine_CXC; Chemokine_CXC: 1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; many members ...