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heatr5b HEAT repeat containing 5B [ Danio rerio (zebrafish) ]

Gene ID: 571772, updated on 27-Mar-2024

Summary

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Official Symbol
heatr5bprovided by ZNC
Official Full Name
HEAT repeat containing 5Bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-130530-676
See related
Ensembl:ENSDARG00000059116 AllianceGenome:ZFIN:ZDB-GENE-130530-676
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to be involved in endocytosis; protein localization; and retrograde transport, endosome to Golgi. Predicted to be active in endocytic vesicle. Orthologous to human HEATR5B (HEAT repeat containing 5B). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See heatr5b in Genome Data Viewer
Location:
chromosome: 13
Exon count:
36
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (447828..480024, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (317542..349712, complement)

Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene vitrin Neighboring gene leucine-rich, glioma inactivated 1a Neighboring gene EGF containing fibulin extracellular matrix protein 1 Neighboring gene F-box protein 28 Neighboring gene delta(4)-desaturase, sphingolipid 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Regulation of cytochrome P450 expression in a novel liver cell line from zebrafish (Brachydanio rerio). Miranda CL, et al. Arch Biochem Biophys, 1993 Sep. PMID 8373170
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein localization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in retrograde transport, endosome to Golgi IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in endocytic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
HEAT repeat-containing protein 5B
Names
zmp:0000000673

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007124.7 Reference GRCz11 Primary Assembly

    Range
    447828..480024 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009307044.3 → XP_009305319.1  HEAT repeat-containing protein 5B

    UniProtKB/TrEMBL
    A0A0R4ISV1, A0A8M3AYT6
    Related
    ENSDARP00000139874.1, ENSDART00000159803.3
    Conserved Domains (1) summary
    sd00044
    Location:851 → 881
    HEAT; HEAT repeat [structural motif]
Nucleotide Protein Strain
Heading Accession and Version

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