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stox2a storkhead box 2a [ Danio rerio (zebrafish) ]

Gene ID: 571741, updated on 27-Mar-2024

Summary

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Official Symbol
stox2aprovided by ZNC
Official Full Name
storkhead box 2aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-090313-101
See related
Ensembl:ENSDARG00000070162 AllianceGenome:ZFIN:ZDB-GENE-090313-101
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
stox2; si:ch211-261d5.6
Summary
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of transcription by RNA polymerase II. Predicted to be active in cytoplasm and nucleus. Orthologous to human STOX2 (storkhead box 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See stox2a in Genome Data Viewer
Location:
chromosome: 1
Exon count:
5
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (39898590..39977359, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (39180519..39259298, complement)

Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene interferon regulatory factor 2a Neighboring gene transmembrane protein 134 Neighboring gene uncharacterized LOC110439845 Neighboring gene inhibitor of growth family, member 2 Neighboring gene superoxide dismutase 3, extracellular b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Transcriptomic analyses reveal novel genes with sexually dimorphic expression in the zebrafish gonad and brain. Sreenivasan R, et al. PLoS One, 2008 Mar 12. PMID 18335061, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
storkhead-box protein 2
Names
storkhead box 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007112.7 Reference GRCz11 Primary Assembly

    Range
    39898590..39977359 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001922863.7 → XP_001922898.3  storkhead-box protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8M1QKU0, F1QWT9
    Related
    ENSDARP00000122521.2, ENSDART00000139354.3
    Conserved Domains (1) summary
    pfam10264
    Location:117 → 193
    Stork_head; Winged helix Storkhead-box1 domain

  2. XM_005160006.4 → XP_005160063.1  storkhead-box protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8M2B6V2, F8W5K8
    Related
    ENSDARP00000125060.1, ENSDART00000149730.3
    Conserved Domains (1) summary
    pfam10264
    Location:68 → 144
    Stork_head; Winged helix Storkhead-box1 domain
Nucleotide Protein Strain
Heading Accession and Version

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