ecpas Ecm29 proteasome adaptor and scaffold [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ecpasprovided by ZNC
Official Full Name: Ecm29 proteasome adaptor and scaffoldprovided by ZNC
Primary source: ZFIN:ZDB-GENE-061207-66
See related: Ensembl:ENSDARG00000061952 AllianceGenome:ZFIN:ZDB-GENE-061207-66
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fbxo10; kiaa0368; si:dkey-245p14.6; si:dkey-245p14.7
Summary: Predicted to enable molecular adaptor activity. Predicted to act upstream of or within proteasome assembly. Predicted to be located in cytoplasm. Orthologous to human ECPAS (Ecm29 proteasome adaptor and scaffold). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 49

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	1	NC_007112.7 (19562751..19599252, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	1	NC_007112.6 (18869814..18906339, complement)

Chromosome 1 - NC_007112.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

fj91f11.y1 (e-PCR)
- UniSTS:200318

Z8718 (e-PCR)
- UniSTS:8366

fc79c04.x1 (e-PCR)
- UniSTS:194542

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables molecular adaptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables molecular adaptor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in ERAD pathway	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within proteasome assembly	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
part_of proteasome complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: proteasome adapter and scaffold protein ECM29

Names: F-box protein 10; zmp:0000000700

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001162486.2 → NP_001155958.1 proteasome adapter and scaffold protein ECM29 isoform 1

Status: VALIDATED

Source sequence(s)

BX548248

UniProtKB/TrEMBL

A0A8M1NT70, B8A5L1

Related

ENSDARP00000083382.5, ENSDART00000088949.7

Conserved Domains (3) summary

pfam12755
Location:1125 → 1210

Vac14_Fab1_bd; Vacuolar 14 Fab1-binding region

pfam13001
Location:10 → 514

Ecm29; Proteasome stabilizer

sd00044
Location:1064 → 1095

HEAT; HEAT repeat [structural motif]
NM_001365155.1 → NP_001352084.1 proteasome adapter and scaffold protein ECM29 isoform 2

Status: VALIDATED

Source sequence(s)

BX548248

UniProtKB/TrEMBL

A0A8M3AZ49

Conserved Domains (2) summary

sd00044
Location:1064 → 1095

HEAT; HEAT repeat [structural motif]

pfam13001
Location:10 → 514

Ecm29; Proteasome stabilizer