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mtcl3a MTCL family member 3a [ Danio rerio (zebrafish) ]

Gene ID: 558933, updated on 11-Apr-2024

Summary

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Official Symbol
mtcl3aprovided by ZNC
Official Full Name
MTCL family member 3aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-100921-84
See related
Ensembl:ENSDARG00000088571 AllianceGenome:ZFIN:ZDB-GENE-100921-84
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
soga3a; si:ch211-151o1.2; si:ch211-151o1.3; si:ch211-151o1.4
Summary
Predicted to act upstream of or within regulation of autophagy. Predicted to be located in extracellular space and membrane. Predicted to be integral component of membrane. Orthologous to several human genes including KIAA0408 (KIAA0408). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See mtcl3a in Genome Data Viewer
Location:
chromosome: 16
Exon count:
8
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (5199376..5231414)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (5299732..5331788)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene ELOVL fatty acid elongase 4a Neighboring gene SOGA family member 3 Neighboring gene enoyl CoA hydratase domain containing 1 Neighboring gene plectin b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. The N-glycome regulates the endothelial-to-hematopoietic transition. Kasper DM, et al. Science, 2020 Dec 4. PMID 33273096, Free PMC Article
  2. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  3. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
  4. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within regulation of autophagy IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
protein SOGA3a; uncharacterized protein KIAA0408-like
Names
SOGA family member 3a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001365850.1 → NP_001352779.1  protein SOGA3a

    Status: VALIDATED

    Source sequence(s)
    AL929535
    UniProtKB/TrEMBL
    A0A8M6YTL1, F1QC39
    Conserved Domains (2) summary
    pfam14818
    Location:201 → 291
    DUF4482; Domain of unknown function (DUF4482)
    cl25732
    Location:63 → 251
    SMC_N; RecF/RecN/SMC N terminal domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    5199376..5231414
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009292035.3 → XP_009290310.2  uncharacterized protein KIAA0408-like isoform X2

    UniProtKB/TrEMBL
    A0A2R8QJ68, A0A8M3AT41
    Related
    ENSDARP00000154214.1, ENSDART00000189704.1

  2. XM_017351457.2 → XP_017206946.1  uncharacterized protein KIAA0408-like isoform X1

    UniProtKB/TrEMBL
    F1QC39
    Related
    ENSDARP00000118055.2, ENSDART00000145368.3
    Conserved Domains (2) summary
    pfam14818
    Location:201 → 291
    DUF4482; Domain of unknown function (DUF4482)
    cl25732
    Location:63 → 251
    SMC_N; RecF/RecN/SMC N terminal domain
Nucleotide Protein Strain
Heading Accession and Version

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