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tecpr1a tectonin beta-propeller repeat containing 1a [ Danio rerio (zebrafish) ]

Gene ID: 556500, updated on 11-Apr-2024

Summary

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Official Symbol
tecpr1aprovided by ZNC
Official Full Name
tectonin beta-propeller repeat containing 1aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-070112-1792
See related
AllianceGenome:ZFIN:ZDB-GENE-070112-1792
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:158759
Summary
Predicted to enable phosphatidylinositol-3-phosphate binding activity. Predicted to be involved in autophagosome maturation. Predicted to be integral component of membrane. Predicted to be active in autophagosome membrane and lysosomal membrane. Orthologous to human TECPR1 (tectonin beta-propeller repeat containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See tecpr1a in Genome Data Viewer
Location:
chromosome: 12
Exon count:
26
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (17760384..17810583, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (17639806..17688692, complement)

Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene microRNA 338-2 Neighboring gene basic helix-loop-helix family, member a15 Neighboring gene BAR/IMD domain containing adaptor protein 2 like 1a Neighboring gene transmembrane protein 130

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Evolution after Whole-Genome Duplication: Teleost MicroRNAs. Desvignes T, et al. Mol Biol Evol, 2021 Jul 29. PMID 33871629, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
tectonin beta-propeller repeat-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007123.7 Reference GRCz11 Primary Assembly

    Range
    17760384..17810583 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021480289.1 → XP_021335964.1  tectonin beta-propeller repeat-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8M9Q8Y3
    Conserved Domains (5) summary
    smart00694
    Location:915 → 948
    DysFC; Dysferlin domain, C-terminal region
    smart00693
    Location:843 → 904
    DysFN; Dysferlin domain, N-terminal region
    smart00706
    Location:233 → 269
    TECPR; Beta propeller repeats in Physarum polycephalum tectonins, Limulus lectin L-6 and animal hypothetical proteins
    pfam06462
    Location:210 → 238
    Hyd_WA; Propeller
    cl17171
    Location:634 → 751
    PH-like; Pleckstrin homology-like domain

  2. XM_021480288.1 → XP_021335963.1  tectonin beta-propeller repeat-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8M9Q8Y3
    Conserved Domains (5) summary
    smart00694
    Location:915 → 948
    DysFC; Dysferlin domain, C-terminal region
    smart00693
    Location:843 → 904
    DysFN; Dysferlin domain, N-terminal region
    smart00706
    Location:233 → 269
    TECPR; Beta propeller repeats in Physarum polycephalum tectonins, Limulus lectin L-6 and animal hypothetical proteins
    pfam06462
    Location:210 → 238
    Hyd_WA; Propeller
    cl17171
    Location:634 → 751
    PH-like; Pleckstrin homology-like domain

  3. XM_009306680.3 → XP_009304955.1  tectonin beta-propeller repeat-containing protein 1 isoform X2

    See identical proteins and their annotated locations for XP_009304955.1

    UniProtKB/TrEMBL
    A0A8M3AYC6
    Conserved Domains (5) summary
    smart00694
    Location:908 → 941
    DysFC; Dysferlin domain, C-terminal region
    smart00693
    Location:836 → 897
    DysFN; Dysferlin domain, N-terminal region
    smart00706
    Location:233 → 269
    TECPR; Beta propeller repeats in Physarum polycephalum tectonins, Limulus lectin L-6 and animal hypothetical proteins
    pfam06462
    Location:210 → 238
    Hyd_WA; Propeller
    cl17171
    Location:624 → 744
    PH-like; Pleckstrin homology-like domain

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001080564.1: Suppressed sequence

    Description
    NM_001080564.1: This RefSeq was suppressed temporarily based on the calculation that the encoded protein was shorter than proteins from the putative ortholog from human: TECPR1 (GeneID:25851).
Nucleotide Protein Strain
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