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srd5a2 steroid 5 alpha-reductase 2 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 549867, updated on 17-Aug-2024

Summary

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Official Symbol
srd5a2provided by Xenbase
Official Full Name
steroid 5 alpha-reductase 2provided by Xenbase
Primary source
Xenbase:XB-GENE-940949
See related
Ensembl:ENSXETG00000025082
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
SRD5alpha2
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
6
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 5 NC_030681.2 (51237349..51275945)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 5 NC_030681.1 (40593254..40630461)

Chromosome 5 - NC_030681.2Genomic Context describing neighboring genes Neighboring gene presenilin 2 Neighboring gene mediator of cell motility 1 Neighboring gene AT-hook containing transcription factor 1 Neighboring gene kinesin-like protein KIF28P Neighboring gene kinesin-like protein 28

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables 3-oxo-5-alpha-steroid 4-dehydrogenase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables 3-oxo-5-alpha-steroid 4-dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
  
enables 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on the CH-CH group of donors IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within androgen biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within lipid metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within sex differentiation IEA
Inferred from Electronic Annotation
more info
  
involved_in steroid biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within steroid metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
3-oxo-5-alpha-steroid 4-dehydrogenase 2
Names
steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
NP_001017113.1
XP_017949395.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001017113.2 → NP_001017113.1  3-oxo-5-alpha-steroid 4-dehydrogenase 2

    Status: PROVISIONAL

    Source sequence(s)
    CR761203
    UniProtKB/TrEMBL
    A0A8J0PJ13
    Related
    ENSXETP00000058743.1, ENSXETT00000062596.3
    Conserved Domains (1) summary
    pfam02544
    Location:105 → 219
    Steroid_dh; 3-oxo-5-alpha-steroid 4-dehydrogenase

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030681.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    51237349..51275945
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018093906.2 → XP_017949395.1  3-oxo-5-alpha-steroid 4-dehydrogenase 2 isoform X1

    UniProtKB/TrEMBL
    A0A6I8PNY4
    Conserved Domains (1) summary
    pfam02544
    Location:105 → 254
    Steroid_dh; 3-oxo-5-alpha-steroid 4-dehydrogenase
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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