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GLYR1 glyoxylate reductase 1 homolog [ Bos taurus (domestic cattle) ]

Gene ID: 539636, updated on 18-Aug-2024

Summary

Official Symbol
GLYR1provided by VGNC
Official Full Name
glyoxylate reductase 1 homologprovided by VGNC
Primary source
VGNC:VGNC:29430
See related
BGD:BT24993; Ensembl:ENSBTAG00000001731
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
NPAC; N-PAC
Orthologs
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Genomic context

Location:
chromosome: 25
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 25 NC_037352.1 (3882633..3914421, complement)

Chromosome 25 - NC_037352.1Genomic Context describing neighboring genes Neighboring gene U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein-like Neighboring gene septin 12 Neighboring gene rogdi atypical leucine zipper Neighboring gene ubinuclein 1 Neighboring gene periplakin

Genomic regions, transcripts, and products

Genomic Sequence:
NC_037352.1 Chromosome 25 Reference ARS-UCD2.0 Primary Assembly

General gene information

Markers

Clone Names

  • MGC137845

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NAD binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables NADP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
cytokine-like nuclear factor N-PAC
Names
cytokine-like nuclear factor n-pac
nuclear protein NP60
putative oxidoreductase GLYR1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001040568.2NP_001035658.2  cytokine-like nuclear factor N-PAC

    See identical proteins and their annotated locations for NP_001035658.2

    Status: PROVISIONAL

    Source sequence(s)
    BC114770
    UniProtKB/Swiss-Prot
    A4FUF0, Q58DC3
    UniProtKB/TrEMBL
    A0A3Q1LGK3
    Related
    ENSBTAP00000002268.5, ENSBTAT00000002268.7
    Conserved Domains (3) summary
    cd05836
    Location:690
    N_Pac_NP60; The PWWP domain is an essential part of the cytokine-like nuclear factor n-pac protein, or NP60, which enhances the activity of MAP2K4 and MAP2K6 kinases to phosphorylate p38-alpha. In a variety of cell lines, NP60 has been shown to localize to the ...
    COG2084
    Location:268551
    MmsB; 3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase [Lipid transport and metabolism]
    cl21454
    Location:210302
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037352.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    3882633..3914421 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059881408.1XP_059737391.1  cytokine-like nuclear factor N-PAC isoform X5

    UniProtKB/TrEMBL
    A0A3Q1LGK3
  2. XM_059881407.1XP_059737390.1  cytokine-like nuclear factor N-PAC isoform X4

    UniProtKB/TrEMBL
    A0A3Q1LGK3, A0AAA9SYG9
    Related
    ENSBTAP00000089139.1, ENSBTAT00000099579.1
  3. XM_059881404.1XP_059737387.1  cytokine-like nuclear factor N-PAC isoform X1

    UniProtKB/TrEMBL
    A0A3Q1LGK3
  4. XM_059881405.1XP_059737388.1  cytokine-like nuclear factor N-PAC isoform X2

    UniProtKB/TrEMBL
    A0A3Q1LR41
  5. XM_059881406.1XP_059737389.1  cytokine-like nuclear factor N-PAC isoform X3

    UniProtKB/TrEMBL
    A0A3Q1LR41