DEPDC1 DEP domain containing 1 [Bos taurus (cattle)] - Gene

Summary

Official Symbol: DEPDC1provided by VGNC
Official Full Name: DEP domain containing 1provided by VGNC
Primary source: VGNC:VGNC:55165
See related: Ensembl:ENSBTAG00000001343
Gene type: protein coding
RefSeq status: MODEL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 3

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	3	NC_037330.1 (76768148..76791498)

Chromosome 3 - NC_037330.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Process	Evidence Code	Pubs
involved_in intracellular signal transduction	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed
part_of transcription repressor complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: DEP domain-containing protein 1A

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

NC_037330.1 Reference ARS-UCD2.0 Primary Assembly

Range

76768148..76791498

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_059885115.1 → XP_059741098.1 DEP domain-containing protein 1A isoform X3

UniProtKB/TrEMBL

E1BA57
XM_059885114.1 → XP_059741097.1 DEP domain-containing protein 1A isoform X1

UniProtKB/TrEMBL

A0AAA9T9M4, E1BA57
XM_015465164.3 → XP_015320650.2 DEP domain-containing protein 1A isoform X1

UniProtKB/TrEMBL

A0AAA9T9M4, E1BA57

Related

ENSBTAP00000094700.1, ENSBTAT00000112444.1

Conserved Domains (3) summary

cd04405
Location:181 → 308

RhoGAP_BRCC3-like; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of BRCC3-like proteins. This subgroup also contains two groups of closely related proteins, BRCC3 and DEPDC7, which both contain a C-terminal RhoGAP-like domain and an N-terminal ...

cl02570
Location:584 → 690

RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

cl02442
Location:15 → 106

DEP; DEP domain, named after Dishevelled, Egl-10, and Pleckstrin, where this domain was first discovered. The function of this domain is still not clear, but it is believed to be important for the membrane association of the signaling proteins in which it is ...
XM_024990115.2 → XP_024845883.1 DEP domain-containing protein 1A isoform X2

UniProtKB/TrEMBL

E1BA57

Related

ENSBTAP00000040158.6, ENSBTAT00000040383.6

Conserved Domains (3) summary

cd04405
Location:181 → 308

RhoGAP_BRCC3-like; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of BRCC3-like proteins. This subgroup also contains two groups of closely related proteins, BRCC3 and DEPDC7, which both contain a C-terminal RhoGAP-like domain and an N-terminal ...

cl02570
Location:584 → 690

RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

cl02442
Location:15 → 106

DEP; DEP domain, named after Dishevelled, Egl-10, and Pleckstrin, where this domain was first discovered. The function of this domain is still not clear, but it is believed to be important for the membrane association of the signaling proteins in which it is ...
XM_015465165.3 → XP_015320651.2 DEP domain-containing protein 1A isoform X4

UniProtKB/TrEMBL

A0AAA9U1A9

Related

ENSBTAP00000103843.1, ENSBTAT00000122738.1

Conserved Domains (2) summary

cd04405
Location:181 → 406

RhoGAP_BRCC3-like; RhoGAP_BRCC3-like: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of BRCC3-like proteins. This subgroup also contains two groups of closely related proteins, BRCC3 and DEPDC7, which both contain a C-terminal RhoGAP-like domain ...

cl02442
Location:15 → 106

DEP; DEP domain, named after Dishevelled, Egl-10, and Pleckstrin, where this domain was first discovered. The function of this domain is still not clear, but it is believed to be important for the membrane association of the signaling proteins in which it is ...