U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

TFE3 transcription factor binding to IGHM enhancer 3 [ Bos taurus (cattle) ]

Gene ID: 520800, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
TFE3provided by VGNC
Official Full Name
transcription factor binding to IGHM enhancer 3provided by VGNC
Primary source
VGNC:VGNC:35787
See related
BGD:BT14180; Ensembl:ENSBTAG00000008523
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: X
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) X NC_037357.1 (87111173..87122680, complement)

Chromosome X - NC_037357.1Genomic Context describing neighboring genes Neighboring gene GRIP1 associated protein 1 Neighboring gene U6 spliceosomal RNA Neighboring gene small nucleolar RNA SNORA16B/SNORA16A family Neighboring gene coiled-coil domain containing 120 Neighboring gene PRA1 domain family member 2

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_037357.1 Chromosome X Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
  2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in humoral immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of osteoclast differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
transcription factor E3

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001075811.2 → NP_001069279.2  transcription factor E3

    See identical proteins and their annotated locations for NP_001069279.2

    Status: PROVISIONAL

    Source sequence(s)
    BC122581
    UniProtKB/Swiss-Prot
    Q05B92
    Conserved Domains (3) summary
    cd00083
    Location:342 → 402
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    pfam11851
    Location:430 → 571
    DUF3371; Domain of unknown function (DUF3371)
    pfam15951
    Location:113 → 263
    MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037357.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    87111173..87122680 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015461673.3 → XP_015317159.1  transcription factor E3 isoform X4

    Conserved Domains (3) summary
    cd00083
    Location:292 → 352
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    pfam11851
    Location:380 → 521
    DUF3371; Domain of unknown function (DUF3371)
    pfam15951
    Location:113 → 197
    MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus

  2. XM_010821906.4 → XP_010820208.1  transcription factor E3 isoform X3

    Related
    ENSBTAP00000011237.5, ENSBTAT00000011237.6
    Conserved Domains (3) summary
    cd00083
    Location:354 → 414
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    pfam11851
    Location:442 → 583
    DUF3371; Domain of unknown function (DUF3371)
    pfam15951
    Location:113 → 263
    MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus

  3. XM_024988020.2 → XP_024843788.1  transcription factor E3 isoform X2

    Conserved Domains (3) summary
    cd00083
    Location:367 → 427
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    pfam11851
    Location:543 → 596
    DUF3371; Domain of unknown function (DUF3371)
    pfam15951
    Location:113 → 259
    MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus

  4. XM_024988019.2 → XP_024843787.1  transcription factor E3 isoform X1

    Related
    ENSBTAP00000096434.1, ENSBTAT00000093581.1
    Conserved Domains (3) summary
    cd00083
    Location:379 → 439
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    pfam11851
    Location:555 → 608
    DUF3371; Domain of unknown function (DUF3371)
    pfam15951
    Location:113 → 259
    MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus

  5. XM_024988021.2 → XP_024843789.1  transcription factor E3 isoform X5

    Conserved Domains (3) summary
    cd00083
    Location:274 → 334
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    pfam11851
    Location:433 → 503
    DUF3371; Domain of unknown function (DUF3371)
    pfam15951
    Location:8 → 154
    MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q05B92.1 GenPept UniProtKB/Swiss-Prot:Q05B92

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Miscellaneous