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CDKN1A cyclin dependent kinase inhibitor 1A [ Bos taurus (domestic cattle) ]

Gene ID: 513497, updated on 17-Aug-2024

Summary

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Official Symbol
CDKN1Aprovided by VGNC
Official Full Name
cyclin dependent kinase inhibitor 1Aprovided by VGNC
Primary source
VGNC:VGNC:27142
See related
BGD:BT10775; Ensembl:ENSBTAG00000008353
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
p21; CIP1; SDI1; WAF1
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 23
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 23 NC_037350.1 (10573389..10590591)

Chromosome 23 - NC_037350.1Genomic Context describing neighboring genes Neighboring gene serine and arginine rich splicing factor 3 Neighboring gene ribosomal protein S4, Y-linked 1 Neighboring gene BLOC-1-related complex subunit 8-like Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037350.1 Chromosome 23 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. p21(Waf1/Cip1) as a molecular sensor for BoHV-4 replication. Capocefalo A, et al. J Virol Methods, 2009 Nov. PMID 19540267
  2. Increased expression of p21Sdi1 in adrenocortical cells when they are placed in culture. Yang L, et al. Exp Cell Res, 1995 Nov. PMID 7589237
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cyclin-dependent protein serine/threonine kinase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction by p53 class mediator IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cyclin-dependent kinase inhibitor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001098958.2 → NP_001092428.1  cyclin-dependent kinase inhibitor 1

    See identical proteins and their annotated locations for NP_001092428.1

    Status: PROVISIONAL

    Source sequence(s)
    BC142538
    UniProtKB/TrEMBL
    A5PKM2
    Related
    ENSBTAP00000011001.4, ENSBTAT00000011001.5
    Conserved Domains (1) summary
    pfam02234
    Location:20 → 63
    CDI; Cyclin-dependent kinase inhibitor

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037350.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    10573389..10590591
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005223326.4 → XP_005223383.1  cyclin-dependent kinase inhibitor 1 isoform X1

    UniProtKB/TrEMBL
    A0AAA9S8H6
    Related
    ENSBTAP00000078458.1, ENSBTAT00000090218.1
    Conserved Domains (1) summary
    pfam02234
    Location:75 → 118
    CDI; Cyclin-dependent kinase inhibitor
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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