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FOLH1 folate hydrolase 1 [ Bos taurus (domestic cattle) ]

Gene ID: 505865, updated on 10-Aug-2024

Summary

Gene symbol
FOLH1
Gene description
folate hydrolase 1
See related
BGD:BT24322; Ensembl:ENSBTAG00000007397
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
FOLH1B
Orthologs
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Genomic context

Location:
chromosome: 29
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 29 NC_037356.1 (5885258..5957949, complement)

Chromosome 29 - NC_037356.1Genomic Context describing neighboring genes Neighboring gene tripartite motif-containing protein 64 Neighboring gene tripartite motif-containing protein 64 Neighboring gene NADPH oxidase 4 Neighboring gene uncharacterized LOC112444878 Neighboring gene tyrosinase

Genomic regions, transcripts, and products

Genomic Sequence:
NC_037356.1 Chromosome 29 Reference ARS-UCD2.0 Primary Assembly

Pathways from PubChem

General protein information

Preferred Names
glutamate carboxypeptidase 2
Names
folate hydrolase (prostate-specific membrane antigen) 1
folate hydrolase 1B
NP_001095328.1
XP_024842790.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001101858.2NP_001095328.1  glutamate carboxypeptidase 2

    See identical proteins and their annotated locations for NP_001095328.1

    Status: PROVISIONAL

    Source sequence(s)
    BC148082
    UniProtKB/TrEMBL
    A0AAA9SMP4, A6QLT8
    Related
    ENSBTAP00000085240.1, ENSBTAT00000091040.1
    Conserved Domains (4) summary
    cd08022
    Location:352595
    M28_PSMA_like; M28 Zn-peptidase prostate-specific membrane antigen
    cd02121
    Location:120346
    PA_GCPII_like; PA_GCPII_like: Protease-associated domain containing protein, glutamate carboxypeptidase II (GCPII)-like. This group contains various PA domain-containing proteins similar to GCPII including, GCPIII (NAALADase2) and NAALADase L. These proteins belong to ...
    pfam04253
    Location:632747
    TFR_dimer; Transferrin receptor-like dimerization domain
    cl14876
    Location:68114
    Zinc_peptidase_like; Zinc peptidases M18, M20, M28, and M42

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037356.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    5885258..5957949 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024987022.2XP_024842790.1  glutamate carboxypeptidase 2 isoform X1

    UniProtKB/TrEMBL
    A0AAA9SMP4, F1MUP1
    Related
    ENSBTAP00000009723.5, ENSBTAT00000009723.6
    Conserved Domains (4) summary
    cd08022
    Location:356599
    M28_PSMA_like; M28 Zn-peptidase prostate-specific membrane antigen
    cd02121
    Location:120350
    PA_GCPII_like; Protease-associated domain containing protein, glutamate carboxypeptidase II (GCPII)-like. This group contains various PA domain-containing proteins similar to GCPII including, GCPIII (NAALADase2) and NAALADase L. These proteins belong to the peptidase ...
    pfam04253
    Location:636747
    TFR_dimer; Transferrin receptor-like dimerisation domain
    cl14876
    Location:68114
    Zinc_peptidase_like; Zinc peptidases M18, M20, M28, and M42