Rspo4 R-spondin 4 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Rspo4provided by RGD
Official Full Name: R-spondin 4provided by RGD
Primary source: RGD:1563415
See related: EnsemblRapid:ENSRNOG00000009662 AllianceGenome:RGD:1563415
Gene type: protein coding
RefSeq status: MODEL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1563415
Summary: Predicted to enable heparin binding activity. Predicted to be involved in positive regulation of Wnt signaling pathway. Predicted to act upstream of or within nail development. Predicted to be located in extracellular region. Human ortholog(s) of this gene implicated in nonsyndromic congenital nail disorder 4. Orthologous to human RSPO4 (R-spondin 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Heart (RPKM 4.1), Lung (RPKM 2.8) and 5 other tissues See more
Orthologs: human mouse all
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Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	3	NC_086021.1 (160817611..160852071)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	3	NC_051338.1 (140357256..140391780)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	3	NC_005102.4 (147358690..147391719)

Chromosome 3 - NC_086021.1 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables heparin binding	IEA Inferred from Electronic Annotation more info
enables signaling receptor binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in Wnt signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in biological_process	ND No biological Data available more info
acts_upstream_of_or_within nail development	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of Wnt signaling pathway	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of canonical Wnt signaling pathway	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info

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The following sections contain reference sequences that belong to a specific genome build. Explain