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Ccdc69 coiled-coil domain containing 69 [ Rattus norvegicus (Norway rat) ]

Gene ID: 497906, updated on 5-Mar-2024

Summary

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Official Symbol
Ccdc69provided by RGD
Official Full Name
coiled-coil domain containing 69provided by RGD
Primary source
RGD:1562251
See related
Ensembl:ENSRNOG00000021370 AllianceGenome:RGD:1562251
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1562251
Summary
Predicted to enable microtubule binding activity. Predicted to be involved in spindle midzone assembly. Predicted to be located in spindle midzone. Predicted to be active in nucleus. Predicted to colocalize with cytoplasm. Orthologous to human CCDC69 (coiled-coil domain containing 69). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Spleen (RPKM 64.0), Thymus (RPKM 61.0) and 7 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Ccdc69 in Genome Data Viewer
Location:
10q22
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (39673984..39701080, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (39173282..39200358, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (40392459..40419567, complement)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene annexin A6 Neighboring gene uncharacterized LOC120095102 Neighboring gene Y box binding protein 1, pseudogene 20 Neighboring gene ganglioside GM2 activator Neighboring gene uncharacterized LOC134480794 Neighboring gene solute carrier family 36, member 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Role of a novel coiled-coil domain-containing protein CCDC69 in regulating central spindle assembly. Pal D, et al. Cell Cycle, 2010 Oct 15. PMID 20962590, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in spindle midzone assembly ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
colocalizes_with cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in spindle midzone ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
coiled-coil domain-containing protein 69

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109031.1 → NP_001102501.1  coiled-coil domain-containing protein 69

    See identical proteins and their annotated locations for NP_001102501.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473948
    UniProtKB/TrEMBL
    A0A8I6AK54, A6HEK7, A6HEK8, D3ZTN8
    Related
    ENSRNOP00000037400.4, ENSRNOT00000039040.5

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    39673984..39701080 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006246395.5 → XP_006246457.1  coiled-coil domain-containing protein 69 isoform X4

    UniProtKB/TrEMBL
    A0A8I6AK54, A6HEK8

  2. XM_063269609.1 → XP_063125679.1  coiled-coil domain-containing protein 69 isoform X1

  3. XM_006246393.4 → XP_006246455.1  coiled-coil domain-containing protein 69 isoform X2

    See identical proteins and their annotated locations for XP_006246455.1

    UniProtKB/TrEMBL
    A0A8I6AK54, A6HEK8

  4. XM_039086564.2 → XP_038942492.1  coiled-coil domain-containing protein 69 isoform X6

  5. XM_063269611.1 → XP_063125681.1  coiled-coil domain-containing protein 69 isoform X6

  6. XM_063269610.1 → XP_063125680.1  coiled-coil domain-containing protein 69 isoform X5

  7. XM_006246394.5 → XP_006246456.1  coiled-coil domain-containing protein 69 isoform X3

RNA

  1. XR_005489904.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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