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CCDC69 coiled-coil domain containing 69 [ Homo sapiens (human) ]

Gene ID: 26112, updated on 23-Nov-2021

Summary

Official Symbol
CCDC69provided by HGNC
Official Full Name
coiled-coil domain containing 69provided by HGNC
Primary source
HGNC:HGNC:24487
See related
Ensembl:ENSG00000198624 MIM:619288
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Broad expression in fat (RPKM 80.7), adrenal (RPKM 50.2) and 21 other tissues See more
Orthologs
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Genomic context

See CCDC69 in Genome Data Viewer
Location:
5q33.1
Exon count:
9
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (151181052..151224092, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (150560613..150603653, complement)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107986463 Neighboring gene platelet derived growth factor receptor like 2, pseudogene Neighboring gene uncharacterized LOC105378230 Neighboring gene GM2 ganglioside activator Neighboring gene solute carrier family 36 member 3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Genetic variants associated with disordered eating.
GeneReviews: Not available
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ13705, DKFZp434C171

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in spindle midzone assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
colocalizes_with cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in midbody IEA
Inferred from Electronic Annotation
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in spindle midzone IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
coiled-coil domain-containing protein 69

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_015621.3NP_056436.2  coiled-coil domain-containing protein 69

    See identical proteins and their annotated locations for NP_056436.2

    Status: VALIDATED

    Source sequence(s)
    AL713742, BC016647, BM927471
    Consensus CDS
    CCDS4312.1
    UniProtKB/Swiss-Prot
    A6NI79
    UniProtKB/TrEMBL
    Q7L2X4
    Related
    ENSP00000347586.2, ENST00000355417.7
    Conserved Domains (1) summary
    TIGR02168
    Location:51270
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    151181052..151224092 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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