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lap3 leucine aminopeptidase 3 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 496537, updated on 17-Aug-2024

Summary

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Official Symbol
lap3provided by Xenbase
Official Full Name
leucine aminopeptidase 3provided by Xenbase
Primary source
Xenbase:XB-GENE-1006711
See related
Ensembl:ENSXETG00000020343
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
LAP-3
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
14
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 1 NC_030677.2 (28472761..28485177)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 1 NC_030677.1 (16445190..16457652, complement)

Chromosome 1 - NC_030677.2Genomic Context describing neighboring genes Neighboring gene quinoid dihydropteridine reductase Neighboring gene clarin 2 Neighboring gene mediator complex subunit 28 Neighboring gene uncharacterized LOC101731905

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables aminopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables carboxypeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables manganese ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metalloaminopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables peptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in proteolysis IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within proteolysis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
cytosol aminopeptidase
Names
LAP
cysteinylglycine-S-conjugate dipeptidase
leucyl aminopeptidase
proline aminopeptidase
prolyl aminopeptidase
NP_001011124.1
XP_012816229.1
XP_017948259.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001011124.2 → NP_001011124.1  cytosol aminopeptidase

    See identical proteins and their annotated locations for NP_001011124.1

    Status: PROVISIONAL

    Source sequence(s)
    BC084523
    UniProtKB/Swiss-Prot
    Q5XGB9
    UniProtKB/TrEMBL
    G1K3J6
    Related
    ENSXETP00000043882.5, ENSXETT00000043882.5
    Conserved Domains (1) summary
    cd00433
    Location:32 → 510
    Peptidase_M17; Cytosol aminopeptidase family, N-terminal and catalytic domains. Family M17 contains zinc- and manganese-dependent exopeptidases ( EC 3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and ...

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030677.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    28472761..28485177
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012960775.3 → XP_012816229.1  cytosol aminopeptidase isoform X2

    UniProtKB/TrEMBL
    A0A6I8R114, G1K3J6
    Related
    ENSXETP00000079530.2, ENSXETT00000102992.2
    Conserved Domains (1) summary
    cd00433
    Location:8 → 486
    Peptidase_M17; Cytosol aminopeptidase family, N-terminal and catalytic domains. Family M17 contains zinc- and manganese-dependent exopeptidases ( EC 3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and ...

  2. XM_018092770.2 → XP_017948259.1  cytosol aminopeptidase isoform X1

    UniProtKB/TrEMBL
    A0A8J0T1Q9, G1K3J6
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5XGB9.1 GenPept UniProtKB/Swiss-Prot:Q5XGB9

Gene LinkOut

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