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CERS6 ceramide synthase 6 [ Canis lupus familiaris (dog) ]

Gene ID: 488387, updated on 5-Mar-2024

Summary

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Official Symbol
CERS6provided by VGNC
Official Full Name
ceramide synthase 6provided by VGNC
Primary source
VGNC:VGNC:39152
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
LASS6
Orthologs
human mouse all
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Genomic context

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See CERS6 in Genome Data Viewer
Location:
chromosome: 36
Exon count:
11
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 36 NC_051840.1 (13421960..13724119)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 36 NC_006618.4 (13317100..13619138)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 36 NC_049257.1 (13607070..13909590)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 36 NC_049296.1 (13508151..13809389)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 36 NC_049777.1 (13494552..13796285)

Chromosome 36 - NC_051840.1Genomic Context describing neighboring genes Neighboring gene serine/threonine kinase 39 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase-like Neighboring gene uncharacterized LOC102154749 Neighboring gene uncharacterized LOC119867824 Neighboring gene uncharacterized LOC119867825 Neighboring gene uncharacterized LOC111094267 Neighboring gene 60S ribosomal protein L4-like Neighboring gene nitric oxide synthase trafficking

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables sphingosine N-acyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ceramide biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LAG1 longevity assurance homolog 6; ceramide synthase 6
Names
LAG1 homolog, ceramide synthase 6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051840.1 Reference ROS_Cfam_1.0

    Range
    13421960..13724119
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038446964.1 → XP_038302892.1  ceramide synthase 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0TUB0
    Conserved Domains (2) summary
    cd00086
    Location:80 → 120
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    pfam03798
    Location:131 → 324
    TRAM_LAG1_CLN8; TLC domain

  2. XM_038446965.1 → XP_038302893.1  ceramide synthase 6 isoform X2

    UniProtKB/TrEMBL
    A0A8C0QTW3, A0A8C0TUB0
    Conserved Domains (2) summary
    cd00086
    Location:80 → 120
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    pfam03798
    Location:131 → 324
    TRAM_LAG1_CLN8; TLC domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049296.1 Alternate UMICH_Zoey_3.1

    Range
    13508151..13809389
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038521035.1 → XP_038376963.1  ceramide synthase 6 isoform X1

    Conserved Domains (2) summary
    cd00086
    Location:80 → 120
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    pfam03798
    Location:131 → 324
    TRAM_LAG1_CLN8; TLC domain

  2. XM_038521036.1 → XP_038376964.1  ceramide synthase 6 isoform X2

    Conserved Domains (2) summary
    cd00086
    Location:80 → 120
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    pfam03798
    Location:131 → 324
    TRAM_LAG1_CLN8; TLC domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049777.1 Alternate UNSW_CanFamBas_1.0

    Range
    13494552..13796285
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038649152.1 → XP_038505080.1  ceramide synthase 6 isoform X1

    Conserved Domains (2) summary
    cd00086
    Location:80 → 120
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    pfam03798
    Location:131 → 324
    TRAM_LAG1_CLN8; TLC domain

  2. XM_038649153.1 → XP_038505081.1  ceramide synthase 6 isoform X2

    Conserved Domains (2) summary
    cd00086
    Location:80 → 120
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    pfam03798
    Location:131 → 324
    TRAM_LAG1_CLN8; TLC domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049257.1 Alternate UU_Cfam_GSD_1.0

    Range
    13607070..13909590
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038584736.1 → XP_038440664.1  ceramide synthase 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0TUB0
    Conserved Domains (2) summary
    cd00086
    Location:80 → 120
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    pfam03798
    Location:131 → 324
    TRAM_LAG1_CLN8; TLC domain

  2. XM_038584737.1 → XP_038440665.1  ceramide synthase 6 isoform X2

    UniProtKB/TrEMBL
    A0A8C0QTW3, A0A8C0TUB0
    Conserved Domains (2) summary
    cd00086
    Location:80 → 120
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    pfam03798
    Location:131 → 324
    TRAM_LAG1_CLN8; TLC domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006618.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    13317100..13619138
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022414687.2 → XP_022270395.2  ceramide synthase 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0TUB0
    Conserved Domains (2) summary
    cd00086
    Location:80 → 120
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    pfam03798
    Location:131 → 324
    TRAM_LAG1_CLN8; TLC domain

  2. XM_038463335.1 → XP_038319263.1  ceramide synthase 6 isoform X2

    UniProtKB/TrEMBL
    A0A8C0QTW3, A0A8C0TUB0
    Conserved Domains (2) summary
    cd00086
    Location:80 → 120
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    pfam03798
    Location:131 → 324
    TRAM_LAG1_CLN8; TLC domain
Nucleotide Protein
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