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TTBK2 tau tubulin kinase 2 [ Canis lupus familiaris (dog) ]

Gene ID: 487520, updated on 5-Mar-2024

Summary

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Official Symbol
TTBK2provided by VGNC
Official Full Name
tau tubulin kinase 2provided by VGNC
Primary source
VGNC:VGNC:47935
See related
Ensembl:ENSCAFG00845021447
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See TTBK2 in Genome Data Viewer
Location:
chromosome: 30
Exon count:
19
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 30 NC_051834.1 (9805161..9980329, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 30 NC_006612.4 (9727322..9903940, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 30 NC_049251.1 (9963590..10137901, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 30 NC_049290.1 (9723659..9897884, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 30 NC_049771.1 (9830739..10018715, complement)

Chromosome 30 - NC_051834.1Genomic Context describing neighboring genes Neighboring gene StAR related lipid transfer domain containing 9 Neighboring gene codanin 1 Neighboring gene heat shock protein HSP 90-alpha-like Neighboring gene uncharacterized LOC111093378 Neighboring gene ubiquitin protein ligase E3 component n-recognin 1 Neighboring gene transmembrane protein 62

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cilium assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-serine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in ciliary basal body IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in ciliary transition zone IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tau-tubulin kinase 2
XP_005638372.1
XP_005638373.1
XP_005638374.1
XP_022268619.1
XP_038298024.1
XP_038298025.1
XP_038298026.1
XP_038298027.1
XP_038298028.1
XP_038298029.1
XP_038298030.1
XP_038317036.1
XP_038372508.1
XP_038372509.1
XP_038372510.1
XP_038372511.1
XP_038372512.1
XP_038372513.1
XP_038372514.1
XP_038436121.1
XP_038436122.1
XP_038436123.1
XP_038436124.1
XP_038436125.1
XP_038436126.1
XP_038436127.1
XP_038500406.1
XP_038500407.1
XP_038500408.1
XP_038500409.1
XP_544644.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051834.1 Reference ROS_Cfam_1.0

    Range
    9805161..9980329 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038442096.1 → XP_038298024.1  tau-tubulin kinase 2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0RPX9, A0A8C0SS16, A0A8I3PHB2
    Conserved Domains (1) summary
    cd14129
    Location:20 → 281
    STKc_TTBK2; Catalytic domain of the Serine/Threonine protein kinase, Tau-Tubulin Kinase 2

  2. XM_038442097.1 → XP_038298025.1  tau-tubulin kinase 2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0RPX9, A0A8C0SS16, A0A8I3PHB2
    Related
    ENSCAFP00845029825.1, ENSCAFT00845038071.1
    Conserved Domains (1) summary
    cd14129
    Location:20 → 281
    STKc_TTBK2; Catalytic domain of the Serine/Threonine protein kinase, Tau-Tubulin Kinase 2

  3. XM_038442098.1 → XP_038298026.1  tau-tubulin kinase 2 isoform X3

    UniProtKB/TrEMBL
    A0A8I3PCB4, A0A8P0NXF3
    Related
    ENSCAFP00845029657.1, ENSCAFT00845037849.1
    Conserved Domains (1) summary
    cl21453
    Location:1 → 188
    PKc_like; Protein Kinases, catalytic domain

  4. XM_038442101.1 → XP_038298029.1  tau-tubulin kinase 2 isoform X1

    UniProtKB/TrEMBL
    A0A8I3PCB4, A0A8P0NXF3
    Conserved Domains (1) summary
    cl21453
    Location:1 → 133
    PKc_like; Protein Kinases, catalytic domain

  5. XM_038442099.1 → XP_038298027.1  tau-tubulin kinase 2 isoform X3

    UniProtKB/TrEMBL
    A0A8I3PCB4, A0A8P0NXF3
    Conserved Domains (1) summary
    cl21453
    Location:1 → 188
    PKc_like; Protein Kinases, catalytic domain

  6. XM_038442100.1 → XP_038298028.1  tau-tubulin kinase 2 isoform X3

    UniProtKB/TrEMBL
    A0A8I3PCB4, A0A8P0NXF3
    Conserved Domains (1) summary
    cl21453
    Location:1 → 188
    PKc_like; Protein Kinases, catalytic domain

  7. XM_038442102.1 → XP_038298030.1  tau-tubulin kinase 2 isoform X1

    UniProtKB/TrEMBL
    A0A8I3PCB4, A0A8P0NXF3
    Conserved Domains (1) summary
    cl21453
    Location:1 → 133
    PKc_like; Protein Kinases, catalytic domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049290.1 Alternate UMICH_Zoey_3.1

    Range
    9723659..9897884 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038516580.1 → XP_038372508.1  tau-tubulin kinase 2 isoform X2

    Conserved Domains (1) summary
    cd14129
    Location:20 → 281
    STKc_TTBK2; Catalytic domain of the Serine/Threonine protein kinase, Tau-Tubulin Kinase 2

  2. XM_038516581.1 → XP_038372509.1  tau-tubulin kinase 2 isoform X2

    Conserved Domains (1) summary
    cd14129
    Location:20 → 281
    STKc_TTBK2; Catalytic domain of the Serine/Threonine protein kinase, Tau-Tubulin Kinase 2

  3. XM_038516582.1 → XP_038372510.1  tau-tubulin kinase 2 isoform X3

    Conserved Domains (1) summary
    cl21453
    Location:1 → 188
    PKc_like; Protein Kinases, catalytic domain

  4. XM_038516585.1 → XP_038372513.1  tau-tubulin kinase 2 isoform X1

    Conserved Domains (1) summary
    cl21453
    Location:1 → 133
    PKc_like; Protein Kinases, catalytic domain

  5. XM_038516583.1 → XP_038372511.1  tau-tubulin kinase 2 isoform X3

    Conserved Domains (1) summary
    cl21453
    Location:1 → 188
    PKc_like; Protein Kinases, catalytic domain

  6. XM_038516584.1 → XP_038372512.1  tau-tubulin kinase 2 isoform X3

    Conserved Domains (1) summary
    cl21453
    Location:1 → 188
    PKc_like; Protein Kinases, catalytic domain

  7. XM_038516586.1 → XP_038372514.1  tau-tubulin kinase 2 isoform X1

    Conserved Domains (1) summary
    cl21453
    Location:1 → 133
    PKc_like; Protein Kinases, catalytic domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049771.1 Alternate UNSW_CanFamBas_1.0

    Range
    9830739..10018715 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038644478.1 → XP_038500406.1  tau-tubulin kinase 2 isoform X2

  2. XM_038644479.1 → XP_038500407.1  tau-tubulin kinase 2 isoform X2

  3. XM_038644480.1 → XP_038500408.1  tau-tubulin kinase 2 isoform X3

  4. XM_038644481.1 → XP_038500409.1  tau-tubulin kinase 2 isoform X3

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049251.1 Alternate UU_Cfam_GSD_1.0

    Range
    9963590..10137901 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038580193.1 → XP_038436121.1  tau-tubulin kinase 2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0RPX9, A0A8C0SS16, A0A8I3PHB2
    Conserved Domains (1) summary
    cd14129
    Location:20 → 281
    STKc_TTBK2; Catalytic domain of the Serine/Threonine protein kinase, Tau-Tubulin Kinase 2

  2. XM_038580194.1 → XP_038436122.1  tau-tubulin kinase 2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0RPX9, A0A8C0SS16, A0A8I3PHB2
    Conserved Domains (1) summary
    cd14129
    Location:20 → 281
    STKc_TTBK2; Catalytic domain of the Serine/Threonine protein kinase, Tau-Tubulin Kinase 2

  3. XM_038580195.1 → XP_038436123.1  tau-tubulin kinase 2 isoform X3

    UniProtKB/TrEMBL
    A0A8I3PCB4, A0A8P0NXF3
    Conserved Domains (1) summary
    cl21453
    Location:1 → 188
    PKc_like; Protein Kinases, catalytic domain

  4. XM_038580198.1 → XP_038436126.1  tau-tubulin kinase 2 isoform X1

    UniProtKB/TrEMBL
    A0A8I3PCB4, A0A8P0NXF3
    Conserved Domains (1) summary
    cl21453
    Location:1 → 133
    PKc_like; Protein Kinases, catalytic domain

  5. XM_038580196.1 → XP_038436124.1  tau-tubulin kinase 2 isoform X3

    UniProtKB/TrEMBL
    A0A8I3PCB4, A0A8P0NXF3
    Conserved Domains (1) summary
    cl21453
    Location:1 → 188
    PKc_like; Protein Kinases, catalytic domain

  6. XM_038580197.1 → XP_038436125.1  tau-tubulin kinase 2 isoform X3

    UniProtKB/TrEMBL
    A0A8I3PCB4, A0A8P0NXF3
    Conserved Domains (1) summary
    cl21453
    Location:1 → 188
    PKc_like; Protein Kinases, catalytic domain

  7. XM_038580199.1 → XP_038436127.1  tau-tubulin kinase 2 isoform X1

    UniProtKB/TrEMBL
    A0A8I3PCB4, A0A8P0NXF3
    Conserved Domains (1) summary
    cl21453
    Location:1 → 133
    PKc_like; Protein Kinases, catalytic domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006612.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    9727322..9903940 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_544644.7 → XP_544644.3  tau-tubulin kinase 2 isoform X2

    See identical proteins and their annotated locations for XP_544644.3

    UniProtKB/TrEMBL
    A0A8C0RPX9, A0A8C0SS16, A0A8I3PHB2
    Conserved Domains (1) summary
    cd14129
    Location:20 → 281
    STKc_TTBK2; Catalytic domain of the Serine/Threonine protein kinase, Tau-Tubulin Kinase 2

  2. XM_005638315.4 → XP_005638372.1  tau-tubulin kinase 2 isoform X2

    See identical proteins and their annotated locations for XP_005638372.1

    UniProtKB/TrEMBL
    A0A8C0RPX9, A0A8C0SS16, A0A8I3PHB2
    Conserved Domains (1) summary
    cd14129
    Location:20 → 281
    STKc_TTBK2; Catalytic domain of the Serine/Threonine protein kinase, Tau-Tubulin Kinase 2

  3. XM_005638316.4 → XP_005638373.1  tau-tubulin kinase 2 isoform X3

    See identical proteins and their annotated locations for XP_005638373.1

    UniProtKB/TrEMBL
    A0A8I3PCB4, A0A8P0NXF3
    Conserved Domains (1) summary
    cl21453
    Location:1 → 188
    PKc_like; Protein Kinases, catalytic domain

  4. XM_022412911.2 → XP_022268619.1  tau-tubulin kinase 2 isoform X1

    UniProtKB/TrEMBL
    A0A8I3PCB4, A0A8P0NXF3
    Conserved Domains (1) summary
    cl21453
    Location:1 → 133
    PKc_like; Protein Kinases, catalytic domain

  5. XM_005638317.4 → XP_005638374.1  tau-tubulin kinase 2 isoform X3

    See identical proteins and their annotated locations for XP_005638374.1

    UniProtKB/TrEMBL
    A0A8I3PCB4, A0A8P0NXF3
    Conserved Domains (1) summary
    cl21453
    Location:1 → 188
    PKc_like; Protein Kinases, catalytic domain

  6. XM_038461108.1 → XP_038317036.1  tau-tubulin kinase 2 isoform X1

    UniProtKB/TrEMBL
    A0A8I3PCB4, A0A8P0NXF3
    Conserved Domains (1) summary
    cl21453
    Location:1 → 133
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
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