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MAP3K11 mitogen-activated protein kinase kinase kinase 11 [ Canis lupus familiaris (dog) ]

Gene ID: 483732, updated on 17-Aug-2024

Summary

Official Symbol
MAP3K11provided by VGNC
Official Full Name
mitogen-activated protein kinase kinase kinase 11provided by VGNC
Primary source
VGNC:VGNC:42967
See related
Ensembl:ENSCAFG00845020324
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

See MAP3K11 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
10
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 18 NC_051822.1 (52630200..52646397)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 18 NC_006600.4 (50201432..50217631)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 18 NC_049239.1 (52094525..52110726)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 18 NC_049278.1 (51730092..51746289)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 18 NC_049759.1 (51304151..51320331)

Chromosome 18 - NC_051822.1Genomic Context describing neighboring genes Neighboring gene signal-induced proliferation-associated 1 Neighboring gene pecanex 3 Neighboring gene potassium two pore domain channel subfamily K member 7 Neighboring gene EH domain binding protein 1 like 1 Neighboring gene uncharacterized LOC111091000 Neighboring gene family with sequence similarity 89 member B

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables JUN kinase kinase kinase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in microtubule-based process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in centrosome IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
LOW QUALITY PROTEIN: mitogen-activated protein kinase kinase kinase 11; mitogen-activated protein kinase kinase kinase 11
XP_038280923.1
XP_038357183.1
XP_038419863.1
XP_038483991.1
XP_540853.6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051822.1 Reference ROS_Cfam_1.0

    Range
    52630200..52646397
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038424995.1XP_038280923.1  mitogen-activated protein kinase kinase kinase 11

    UniProtKB/TrEMBL
    A0A8C0KQN7, A0A8C0N3H6, A0A8I3PD03
    Related
    ENSCAFP00845028041.1, ENSCAFT00845035840.1
    Conserved Domains (2) summary
    cd12059
    Location:45102
    SH3_MLK1-3; Src Homology 3 domain of Mixed Lineage Kinases 1, 2, and 3
    cd14147
    Location:113379
    STKc_MLK3; Catalytic domain of the Serine/Threonine Kinase, Mixed Lineage Kinase 3

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049278.1 Alternate UMICH_Zoey_3.1

    Range
    51730092..51746289
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038501255.1XP_038357183.1  mitogen-activated protein kinase kinase kinase 11

    Conserved Domains (2) summary
    cd12059
    Location:45102
    SH3_MLK1-3; Src Homology 3 domain of Mixed Lineage Kinases 1, 2, and 3
    cd14147
    Location:113379
    STKc_MLK3; Catalytic domain of the Serine/Threonine Kinase, Mixed Lineage Kinase 3

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049759.1 Alternate UNSW_CanFamBas_1.0

    Range
    51304151..51320331
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038628063.1XP_038483991.1  LOW QUALITY PROTEIN: mitogen-activated protein kinase kinase kinase 11

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049239.1 Alternate UU_Cfam_GSD_1.0

    Range
    52094525..52110726
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038563935.1XP_038419863.1  mitogen-activated protein kinase kinase kinase 11

    UniProtKB/TrEMBL
    A0A8C0KQN7, A0A8C0N3H6, A0A8I3PD03
    Conserved Domains (2) summary
    cd12059
    Location:45102
    SH3_MLK1-3; Src Homology 3 domain of Mixed Lineage Kinases 1, 2, and 3
    cd14147
    Location:113379
    STKc_MLK3; Catalytic domain of the Serine/Threonine Kinase, Mixed Lineage Kinase 3

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006600.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    50201432..50217631
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_540853.7XP_540853.6  mitogen-activated protein kinase kinase kinase 11

    UniProtKB/TrEMBL
    A0A8C0KQN7, A0A8C0N3H6, A0A8I3PD03
    Conserved Domains (2) summary
    cd12059
    Location:45102
    SH3_MLK1-3; Src Homology 3 domain of Mixed Lineage Kinases 1, 2, and 3
    cd14147
    Location:113379
    STKc_MLK3; Catalytic domain of the Serine/Threonine Kinase, Mixed Lineage Kinase 3