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PC pyruvate carboxylase [ Canis lupus familiaris (dog) ]

Gene ID: 483704, updated on 17-Aug-2024

Summary

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Official Symbol
PCprovided by VGNC
Official Full Name
pyruvate carboxylaseprovided by VGNC
Primary source
VGNC:VGNC:51885
See related
Ensembl:ENSCAFG00845011738
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 18
Exon count:
25
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 18 NC_051822.1 (51357399..51457857)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 18 NC_006600.4 (49016958..49117517)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 18 NC_049239.1 (50910958..51011409)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 18 NC_049278.1 (50541749..50642299)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 18 NC_049759.1 (50121287..50221660)

Chromosome 18 - NC_051822.1Genomic Context describing neighboring genes Neighboring gene lateral signaling target protein 2 homolog Neighboring gene chromosome 18 C11orf86 homolog Neighboring gene uncharacterized LOC111090994 Neighboring gene leucine rich repeat and fibronectin type III domain containing 4 Neighboring gene TOP6B like initiator of meiotic double strand breaks Neighboring gene Ras converting CAAX endopeptidase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables pyruvate carboxylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in gluconeogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in pyruvate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
pyruvate carboxylase, mitochondrial
XP_005631472.1
XP_005631473.1
XP_038280769.1
XP_038280770.1
XP_038280771.1
XP_038280772.1
XP_038310442.1
XP_038357013.1
XP_038357014.1
XP_038357015.1
XP_038357016.1
XP_038419712.1
XP_038419713.1
XP_038419714.1
XP_038419715.1
XP_038483830.1
XP_038483831.1
XP_038483832.1
XP_038483833.1
XP_540825.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051822.1 Reference ROS_Cfam_1.0

    Range
    51357399..51457857
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038424843.1 → XP_038280771.1  pyruvate carboxylase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8C0NP94
    Related
    ENSCAFP00845016350.1, ENSCAFT00845020828.1
    Conserved Domains (1) summary
    PRK12999
    Location:33 → 1178
    PRK12999; pyruvate carboxylase; Reviewed

  2. XM_038424842.1 → XP_038280770.1  pyruvate carboxylase, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A8C0NP94, A0A8I3NKZ1, A0A8P0PBZ5
    Related
    ENSCAFP00845016398.1, ENSCAFT00845020879.1
    Conserved Domains (1) summary
    PRK12999
    Location:45 → 1190
    PRK12999; pyruvate carboxylase; Reviewed

  3. XM_038424841.1 → XP_038280769.1  pyruvate carboxylase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8C0NP94
    Conserved Domains (1) summary
    PRK12999
    Location:33 → 1178
    PRK12999; pyruvate carboxylase; Reviewed

  4. XM_038424844.1 → XP_038280772.1  pyruvate carboxylase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8C0NP94
    Conserved Domains (1) summary
    PRK12999
    Location:33 → 1178
    PRK12999; pyruvate carboxylase; Reviewed

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049278.1 Alternate UMICH_Zoey_3.1

    Range
    50541749..50642299
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038501087.1 → XP_038357015.1  pyruvate carboxylase, mitochondrial isoform X1

    Conserved Domains (1) summary
    PRK12999
    Location:33 → 1178
    PRK12999; pyruvate carboxylase; Reviewed

  2. XM_038501086.1 → XP_038357014.1  pyruvate carboxylase, mitochondrial isoform X2

    Conserved Domains (1) summary
    PRK12999
    Location:45 → 1190
    PRK12999; pyruvate carboxylase; Reviewed

  3. XM_038501085.1 → XP_038357013.1  pyruvate carboxylase, mitochondrial isoform X1

    Conserved Domains (1) summary
    PRK12999
    Location:33 → 1178
    PRK12999; pyruvate carboxylase; Reviewed

  4. XM_038501088.1 → XP_038357016.1  pyruvate carboxylase, mitochondrial isoform X1

    Conserved Domains (1) summary
    PRK12999
    Location:33 → 1178
    PRK12999; pyruvate carboxylase; Reviewed

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049759.1 Alternate UNSW_CanFamBas_1.0

    Range
    50121287..50221660
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038627904.1 → XP_038483832.1  pyruvate carboxylase, mitochondrial isoform X1

    Conserved Domains (1) summary
    PRK12999
    Location:33 → 1178
    PRK12999; pyruvate carboxylase; Reviewed

  2. XM_038627903.1 → XP_038483831.1  pyruvate carboxylase, mitochondrial isoform X2

    Conserved Domains (1) summary
    PRK12999
    Location:45 → 1190
    PRK12999; pyruvate carboxylase; Reviewed

  3. XM_038627902.1 → XP_038483830.1  pyruvate carboxylase, mitochondrial isoform X1

    Conserved Domains (1) summary
    PRK12999
    Location:33 → 1178
    PRK12999; pyruvate carboxylase; Reviewed

  4. XM_038627905.1 → XP_038483833.1  pyruvate carboxylase, mitochondrial isoform X1

    Conserved Domains (1) summary
    PRK12999
    Location:33 → 1178
    PRK12999; pyruvate carboxylase; Reviewed

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049239.1 Alternate UU_Cfam_GSD_1.0

    Range
    50910958..51011409
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038563786.1 → XP_038419714.1  pyruvate carboxylase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8C0NP94
    Conserved Domains (1) summary
    PRK12999
    Location:33 → 1178
    PRK12999; pyruvate carboxylase; Reviewed

  2. XM_038563785.1 → XP_038419713.1  pyruvate carboxylase, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A8C0NP94, A0A8I3NKZ1, A0A8P0PBZ5
    Conserved Domains (1) summary
    PRK12999
    Location:45 → 1190
    PRK12999; pyruvate carboxylase; Reviewed

  3. XM_038563784.1 → XP_038419712.1  pyruvate carboxylase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8C0NP94
    Conserved Domains (1) summary
    PRK12999
    Location:33 → 1178
    PRK12999; pyruvate carboxylase; Reviewed

  4. XM_038563787.1 → XP_038419715.1  pyruvate carboxylase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8C0NP94
    Conserved Domains (1) summary
    PRK12999
    Location:33 → 1178
    PRK12999; pyruvate carboxylase; Reviewed

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006600.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    49016958..49117517
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_540825.7 → XP_540825.2  pyruvate carboxylase, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_540825.2

    UniProtKB/TrEMBL
    A0A8C0NP94
    Conserved Domains (1) summary
    PRK12999
    Location:33 → 1178
    PRK12999; pyruvate carboxylase; Reviewed

  2. XM_005631415.4 → XP_005631472.1  pyruvate carboxylase, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A8C0NP94, A0A8I3NKZ1, A0A8P0PBZ5
    Conserved Domains (1) summary
    PRK12999
    Location:45 → 1190
    PRK12999; pyruvate carboxylase; Reviewed

  3. XM_038454514.1 → XP_038310442.1  pyruvate carboxylase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8C0NP94
    Conserved Domains (1) summary
    PRK12999
    Location:33 → 1178
    PRK12999; pyruvate carboxylase; Reviewed

  4. XM_005631416.4 → XP_005631473.1  pyruvate carboxylase, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_005631473.1

    UniProtKB/TrEMBL
    A0A8C0NP94
    Conserved Domains (1) summary
    PRK12999
    Location:33 → 1178
    PRK12999; pyruvate carboxylase; Reviewed
Nucleotide Protein
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