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IL1R1 interleukin 1 receptor type 1 [ Canis lupus familiaris (dog) ]

Gene ID: 481328, updated on 17-Aug-2024

Summary

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Official Symbol
IL1R1provided by VGNC
Official Full Name
interleukin 1 receptor type 1provided by VGNC
Primary source
VGNC:VGNC:41958
See related
Ensembl:ENSCAFG00845010716
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
16
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 10 NC_051814.1 (41692476..41764370, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 10 NC_006592.4 (40751798..40823679, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 10 NC_049231.1 (41880427..41952281, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 10 NC_049270.1 (41406689..41478437, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 10 NC_049751.1 (41688685..41760634, complement)

Chromosome 10 - NC_051814.1Genomic Context describing neighboring genes Neighboring gene interleukin 1 receptor like 2 Neighboring gene uncharacterized LOC119873772 Neighboring gene U6 spliceosomal RNA Neighboring gene small ubiquitin-related modifier 1-like Neighboring gene interleukin 1 receptor type 2 Neighboring gene mitogen-activated protein kinase kinase kinase kinase 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables interleukin-1, type I, activating receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
interleukin-1 receptor type 1
XP_005626056.1
XP_005626059.1
XP_013972907.1
XP_038344871.1
XP_038344872.1
XP_038344873.1
XP_038344874.1
XP_038406852.1
XP_038406853.1
XP_038406854.1
XP_038406855.1
XP_038470759.1
XP_038470760.1
XP_038470761.1
XP_038536134.1
XP_038536135.1
XP_038536136.1
XP_038536137.1
XP_538449.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051814.1 Reference ROS_Cfam_1.0

    Range
    41692476..41764370 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038680208.1 → XP_038536136.1  interleukin-1 receptor type 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0QF36, A0A8C0QPU8, A0A8I3NH34
    Related
    ENSCAFP00845014861.1, ENSCAFT00845019024.1
    Conserved Domains (4) summary
    smart00255
    Location:384 → 540
    TIR; Toll - interleukin 1 - resistance
    cd00096
    Location:226 → 229
    Ig; Ig strand A [structural motif]
    cd20991
    Location:24 → 114
    Ig1_IL1R_like; First immunoglobulin (Ig)-like domain of interleukin-1 receptor (IL1R), and similar domains
    cl11960
    Location:226 → 329
    Ig; Immunoglobulin domain

  2. XM_038680209.1 → XP_038536137.1  interleukin-1 receptor type 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0QF36, A0A8C0QPU8, A0A8I3NH34
    Related
    ENSCAFP00845014813.1, ENSCAFT00845018960.1
    Conserved Domains (4) summary
    smart00255
    Location:384 → 540
    TIR; Toll - interleukin 1 - resistance
    cd00096
    Location:226 → 229
    Ig; Ig strand A [structural motif]
    cd20991
    Location:24 → 114
    Ig1_IL1R_like; First immunoglobulin (Ig)-like domain of interleukin-1 receptor (IL1R), and similar domains
    cl11960
    Location:226 → 329
    Ig; Immunoglobulin domain

  3. XM_038680207.1 → XP_038536135.1  interleukin-1 receptor type 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QLC9, A0A8C0QPU8, A0A8I3RY59
    Related
    ENSCAFP00845014775.1, ENSCAFT00845018911.1
    Conserved Domains (4) summary
    smart00255
    Location:441 → 597
    TIR; Toll - interleukin 1 - resistance
    cd00096
    Location:283 → 286
    Ig; Ig strand A [structural motif]
    cd20991
    Location:81 → 171
    Ig1_IL1R_like; First immunoglobulin (Ig)-like domain of interleukin-1 receptor (IL1R), and similar domains
    cl11960
    Location:283 → 386
    Ig; Immunoglobulin domain

  4. XM_038680206.1 → XP_038536134.1  interleukin-1 receptor type 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QLC9, A0A8C0QPU8, A0A8I3RY59
    Conserved Domains (4) summary
    smart00255
    Location:441 → 597
    TIR; Toll - interleukin 1 - resistance
    cd00096
    Location:283 → 286
    Ig; Ig strand A [structural motif]
    cd20991
    Location:81 → 171
    Ig1_IL1R_like; First immunoglobulin (Ig)-like domain of interleukin-1 receptor (IL1R), and similar domains
    cl11960
    Location:283 → 386
    Ig; Immunoglobulin domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049270.1 Alternate UMICH_Zoey_3.1

    Range
    41406689..41478437 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038488945.1 → XP_038344873.1  interleukin-1 receptor type 1 isoform X2

    Conserved Domains (4) summary
    smart00255
    Location:384 → 540
    TIR; Toll - interleukin 1 - resistance
    cd00096
    Location:226 → 229
    Ig; Ig strand A [structural motif]
    cd20991
    Location:24 → 114
    Ig1_IL1R_like; First immunoglobulin (Ig)-like domain of interleukin-1 receptor (IL1R), and similar domains
    cl11960
    Location:226 → 329
    Ig; Immunoglobulin domain

  2. XM_038488946.1 → XP_038344874.1  interleukin-1 receptor type 1 isoform X2

    Conserved Domains (4) summary
    smart00255
    Location:384 → 540
    TIR; Toll - interleukin 1 - resistance
    cd00096
    Location:226 → 229
    Ig; Ig strand A [structural motif]
    cd20991
    Location:24 → 114
    Ig1_IL1R_like; First immunoglobulin (Ig)-like domain of interleukin-1 receptor (IL1R), and similar domains
    cl11960
    Location:226 → 329
    Ig; Immunoglobulin domain

  3. XM_038488944.1 → XP_038344872.1  interleukin-1 receptor type 1 isoform X1

    Conserved Domains (4) summary
    smart00255
    Location:441 → 597
    TIR; Toll - interleukin 1 - resistance
    cd00096
    Location:283 → 286
    Ig; Ig strand A [structural motif]
    cd20991
    Location:81 → 171
    Ig1_IL1R_like; First immunoglobulin (Ig)-like domain of interleukin-1 receptor (IL1R), and similar domains
    cl11960
    Location:283 → 386
    Ig; Immunoglobulin domain

  4. XM_038488943.1 → XP_038344871.1  interleukin-1 receptor type 1 isoform X1

    Conserved Domains (4) summary
    smart00255
    Location:441 → 597
    TIR; Toll - interleukin 1 - resistance
    cd00096
    Location:283 → 286
    Ig; Ig strand A [structural motif]
    cd20991
    Location:81 → 171
    Ig1_IL1R_like; First immunoglobulin (Ig)-like domain of interleukin-1 receptor (IL1R), and similar domains
    cl11960
    Location:283 → 386
    Ig; Immunoglobulin domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049751.1 Alternate UNSW_CanFamBas_1.0

    Range
    41688685..41760634 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038614832.1 → XP_038470760.1  interleukin-1 receptor type 1 isoform X2

  2. XM_038614833.1 → XP_038470761.1  interleukin-1 receptor type 1 isoform X2

  3. XM_038614831.1 → XP_038470759.1  interleukin-1 receptor type 1 isoform X1

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049231.1 Alternate UU_Cfam_GSD_1.0

    Range
    41880427..41952281 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038550926.1 → XP_038406854.1  interleukin-1 receptor type 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0QF36, A0A8C0QPU8, A0A8I3NH34
    Conserved Domains (4) summary
    smart00255
    Location:384 → 540
    TIR; Toll - interleukin 1 - resistance
    cd00096
    Location:226 → 229
    Ig; Ig strand A [structural motif]
    cd20991
    Location:24 → 114
    Ig1_IL1R_like; First immunoglobulin (Ig)-like domain of interleukin-1 receptor (IL1R), and similar domains
    cl11960
    Location:226 → 329
    Ig; Immunoglobulin domain

  2. XM_038550927.1 → XP_038406855.1  interleukin-1 receptor type 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0QF36, A0A8C0QPU8, A0A8I3NH34
    Conserved Domains (4) summary
    smart00255
    Location:384 → 540
    TIR; Toll - interleukin 1 - resistance
    cd00096
    Location:226 → 229
    Ig; Ig strand A [structural motif]
    cd20991
    Location:24 → 114
    Ig1_IL1R_like; First immunoglobulin (Ig)-like domain of interleukin-1 receptor (IL1R), and similar domains
    cl11960
    Location:226 → 329
    Ig; Immunoglobulin domain

  3. XM_038550924.1 → XP_038406852.1  interleukin-1 receptor type 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QLC9, A0A8C0QPU8, A0A8I3RY59
    Conserved Domains (4) summary
    smart00255
    Location:441 → 597
    TIR; Toll - interleukin 1 - resistance
    cd00096
    Location:283 → 286
    Ig; Ig strand A [structural motif]
    cd20991
    Location:81 → 171
    Ig1_IL1R_like; First immunoglobulin (Ig)-like domain of interleukin-1 receptor (IL1R), and similar domains
    cl11960
    Location:283 → 386
    Ig; Immunoglobulin domain

  4. XM_038550925.1 → XP_038406853.1  interleukin-1 receptor type 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QLC9, A0A8C0QPU8, A0A8I3RY59
    Conserved Domains (4) summary
    smart00255
    Location:441 → 597
    TIR; Toll - interleukin 1 - resistance
    cd00096
    Location:283 → 286
    Ig; Ig strand A [structural motif]
    cd20991
    Location:81 → 171
    Ig1_IL1R_like; First immunoglobulin (Ig)-like domain of interleukin-1 receptor (IL1R), and similar domains
    cl11960
    Location:283 → 386
    Ig; Immunoglobulin domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006592.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    40751798..40823679 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005626002.4 → XP_005626059.1  interleukin-1 receptor type 1 isoform X2

    See identical proteins and their annotated locations for XP_005626059.1

    UniProtKB/TrEMBL
    A0A8C0QF36, A0A8C0QPU8, A0A8I3NH34
    Conserved Domains (4) summary
    smart00255
    Location:384 → 540
    TIR; Toll - interleukin 1 - resistance
    cd00096
    Location:226 → 229
    Ig; Ig strand A [structural motif]
    cd20991
    Location:24 → 114
    Ig1_IL1R_like; First immunoglobulin (Ig)-like domain of interleukin-1 receptor (IL1R), and similar domains
    cl11960
    Location:226 → 329
    Ig; Immunoglobulin domain

  2. XM_538449.7 → XP_538449.3  interleukin-1 receptor type 1 isoform X2

    See identical proteins and their annotated locations for XP_538449.3

    UniProtKB/TrEMBL
    A0A8C0QF36, A0A8C0QPU8, A0A8I3NH34
    Conserved Domains (4) summary
    smart00255
    Location:384 → 540
    TIR; Toll - interleukin 1 - resistance
    cd00096
    Location:226 → 229
    Ig; Ig strand A [structural motif]
    cd20991
    Location:24 → 114
    Ig1_IL1R_like; First immunoglobulin (Ig)-like domain of interleukin-1 receptor (IL1R), and similar domains
    cl11960
    Location:226 → 329
    Ig; Immunoglobulin domain

  3. XM_005625999.4 → XP_005626056.1  interleukin-1 receptor type 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QLC9, A0A8C0QPU8, A0A8I3RY59
    Conserved Domains (4) summary
    smart00255
    Location:441 → 597
    TIR; Toll - interleukin 1 - resistance
    cd00096
    Location:283 → 286
    Ig; Ig strand A [structural motif]
    cd20991
    Location:81 → 171
    Ig1_IL1R_like; First immunoglobulin (Ig)-like domain of interleukin-1 receptor (IL1R), and similar domains
    cl11960
    Location:283 → 386
    Ig; Immunoglobulin domain

  4. XM_014117432.3 → XP_013972907.1  interleukin-1 receptor type 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QLC9, A0A8C0QPU8, A0A8I3RY59
    Conserved Domains (4) summary
    smart00255
    Location:441 → 597
    TIR; Toll - interleukin 1 - resistance
    cd00096
    Location:283 → 286
    Ig; Ig strand A [structural motif]
    cd20991
    Location:81 → 171
    Ig1_IL1R_like; First immunoglobulin (Ig)-like domain of interleukin-1 receptor (IL1R), and similar domains
    cl11960
    Location:283 → 386
    Ig; Immunoglobulin domain
Nucleotide Protein
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