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KPNA2 karyopherin subunit alpha 2 [ Canis lupus familiaris (dog) ]

Gene ID: 480469, updated on 5-Mar-2024

Summary

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Gene symbol
KPNA2
Gene description
karyopherin subunit alpha 2
See related
Ensembl:ENSCAFG00845024319
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 9
Exon count:
12
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (14205539..14214799, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (13442712..13451963, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (14369408..14378660)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (13154710..13163965, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (14370477..14379722)

Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene DEAD-box helicase 5 Neighboring gene centrosomal protein 95 Neighboring gene SMAD specific E3 ubiquitin protein ligase 2 Neighboring gene transfer RNA arginine (anticodon CCG) Neighboring gene chromosome 9 C17orf58 homolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables nuclear import signal receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear localization sequence binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in NLS-bearing protein import into nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
importin subunit alpha-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051813.1 Reference ROS_Cfam_1.0

    Range
    14205539..14214799 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038676038.1 → XP_038531966.1  importin subunit alpha-1

    UniProtKB/TrEMBL
    A0A8C0LLW1, A0A8C0NGB8, A0A8I3PRA9, A0A8P0NSR6
    Related
    ENSCAFP00845033673.1, ENSCAFT00845042955.1
    Conserved Domains (2) summary
    COG5064
    Location:10 → 528
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00043
    Location:253 → 278
    ARM; armadillo repeat [structural motif]

  2. XM_038676039.1 → XP_038531967.1  importin subunit alpha-1

    UniProtKB/TrEMBL
    A0A8C0LLW1, A0A8C0NGB8, A0A8I3PRA9, A0A8P0NSR6
    Conserved Domains (2) summary
    COG5064
    Location:10 → 528
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00043
    Location:253 → 278
    ARM; armadillo repeat [structural motif]

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049269.1 Alternate UMICH_Zoey_3.1

    Range
    13154710..13163965 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038485190.1 → XP_038341118.1  importin subunit alpha-1

    Conserved Domains (2) summary
    COG5064
    Location:10 → 528
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00043
    Location:253 → 278
    ARM; armadillo repeat [structural motif]

  2. XM_038485191.1 → XP_038341119.1  importin subunit alpha-1

    Conserved Domains (2) summary
    COG5064
    Location:10 → 528
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00043
    Location:253 → 278
    ARM; armadillo repeat [structural motif]

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

    Range
    14370477..14379722
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038610818.1 → XP_038466746.1  importin subunit alpha-1

    Conserved Domains (2) summary
    COG5064
    Location:10 → 528
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00043
    Location:253 → 278
    ARM; armadillo repeat [structural motif]

  2. XM_038610819.1 → XP_038466747.1  importin subunit alpha-1

    Conserved Domains (2) summary
    COG5064
    Location:10 → 528
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00043
    Location:253 → 278
    ARM; armadillo repeat [structural motif]

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

    Range
    14369408..14378660
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038546845.1 → XP_038402773.1  importin subunit alpha-1

    UniProtKB/TrEMBL
    A0A8C0LLW1, A0A8C0NGB8, A0A8I3PRA9, A0A8P0NSR6
    Conserved Domains (2) summary
    COG5064
    Location:10 → 528
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00043
    Location:253 → 278
    ARM; armadillo repeat [structural motif]

  2. XM_038546846.1 → XP_038402774.1  importin subunit alpha-1

    UniProtKB/TrEMBL
    A0A8C0LLW1, A0A8C0NGB8, A0A8I3PRA9, A0A8P0NSR6
    Conserved Domains (2) summary
    COG5064
    Location:10 → 528
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00043
    Location:253 → 278
    ARM; armadillo repeat [structural motif]

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    13442712..13451963 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_856897.6 → XP_861990.1  importin subunit alpha-1

    See identical proteins and their annotated locations for XP_861990.1

    UniProtKB/TrEMBL
    A0A8C0LLW1, A0A8C0NGB8, A0A8I3PRA9, A0A8P0NSR6
    Conserved Domains (2) summary
    COG5064
    Location:10 → 528
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00043
    Location:253 → 278
    ARM; armadillo repeat [structural motif]

  2. XM_005624265.3 → XP_005624322.1  importin subunit alpha-1

    See identical proteins and their annotated locations for XP_005624322.1

    UniProtKB/TrEMBL
    A0A8C0LLW1, A0A8C0NGB8, A0A8I3PRA9, A0A8P0NSR6
    Conserved Domains (2) summary
    COG5064
    Location:10 → 528
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00043
    Location:253 → 278
    ARM; armadillo repeat [structural motif]
Nucleotide Protein
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