APOA2 apolipoprotein A2 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: APOA2provided by VGNC
Official Full Name: apolipoprotein A2provided by VGNC
Primary source: VGNC:VGNC:37992
See related: Ensembl:ENSCAFG00845029343
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as: Apo-AII; ApoA-II
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 38

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	38	NC_051842.1 (21381461..21383727)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	38	NC_006620.4 (21338500..21340743)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	38	NC_049259.1 (22092910..22095161)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	38	NC_049298.1 (21278560..21279234)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	38	NC_049779.1 (21683795..21686027)

Chromosome 38 - NC_051842.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables apolipoprotein receptor binding	IEA Inferred from Electronic Annotation more info	PubMed
enables cholesterol binding	IEA Inferred from Electronic Annotation more info	PubMed
enables high-density lipoprotein particle binding	IEA Inferred from Electronic Annotation more info	PubMed
enables high-density lipoprotein particle receptor binding	IEA Inferred from Electronic Annotation more info	PubMed
enables lipase inhibitor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables phosphatidylcholine binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cholesterol homeostasis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cholesterol metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cholesterol transport	IEA Inferred from Electronic Annotation more info	PubMed
involved_in high-density lipoprotein particle assembly	IEA Inferred from Electronic Annotation more info	PubMed
involved_in high-density lipoprotein particle remodeling	IEA Inferred from Electronic Annotation more info	PubMed
involved_in lipoprotein metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in low-density lipoprotein particle remodeling	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of lipase activity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in triglyceride-rich lipoprotein particle remodeling	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in blood microparticle	IEA Inferred from Electronic Annotation more info	PubMed
part_of chylomicron	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed
part_of spherical high-density lipoprotein particle	IEA Inferred from Electronic Annotation more info	PubMed
part_of very-low-density lipoprotein particle	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: apolipoprotein A-II

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001313799.1 → NP_001300728.1 apolipoprotein A-II precursor

Status: VALIDATED

Source sequence(s)

JAAUVH010000370

UniProtKB/Swiss-Prot

E2RAK7

UniProtKB/TrEMBL

A0A8C0JHW7, A0A8C0RNZ9

Related

ENSCAFP00845040756.1, ENSCAFT00845051946.1

Conserved Domains (1) summary

pfam04711
Location:24 → 98

ApoA-II; Apolipoprotein A-II (ApoA-II)