PDE9A phosphodiesterase 9A [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: PDE9Aprovided by VGNC
Official Full Name: phosphodiesterase 9Aprovided by VGNC
Primary source: VGNC:VGNC:1134
Locus tag: CK820_G0022880
See related: Ensembl:ENSPTRG00000013946
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 21

Exon count:: 23

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	22	NC_072420.2 (43305468..43428546)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	21	NC_072419.1 (40958259..41081299)

Chromosome 22 - NC_072420.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

STS_CEB239 (e-PCR)
- UniSTS:255244

SHGC-105989 (e-PCR)
- UniSTS:169552

SHGC-87675 (e-PCR)
- UniSTS:63583

IB381 (e-PCR)
- UniSTS:45160

SHGC-57530 (e-PCR)
- UniSTS:12937

D21S1411 (e-PCR), detects polymorphism
- UniSTS:19353

D21S113 (e-PCR)
- UniSTS:147879

RH78209 (e-PCR)
- UniSTS:66757

D21S1974 (e-PCR)
- UniSTS:7638

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables 3',5'-cyclic-GMP phosphodiesterase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cGMP catabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in signal transduction	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

Names: High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

XP_001140087.3

EC 3.1.4.35

XP_001140174.3

EC 3.1.4.35

XP_024208206.1

EC 3.1.4.35

XP_063659577.1

EC 3.1.4.35

XP_063659578.1

EC 3.1.4.35

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072420.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

43305468..43428546

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_001140087.8 → XP_001140087.3 high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A isoform X2

UniProtKB/TrEMBL

A0A2J8M8B4, A0A2J8M8C1

Conserved Domains (1) summary

pfam00233
Location:251 → 479

PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
XM_063803507.1 → XP_063659577.1 high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A isoform X4

UniProtKB/TrEMBL

A0A2J8M8B8
XM_001140174.8 → XP_001140174.3 high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A isoform X1

UniProtKB/Swiss-Prot

H2QL32, K7AGW3

UniProtKB/TrEMBL

A0A2J8M8C0, A0A2K6HIZ1

Conserved Domains (1) summary

pfam00233
Location:311 → 539

PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
XM_024352438.3 → XP_024208206.1 high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A isoform X3

Conserved Domains (1) summary

pfam00233
Location:311 → 452

PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
XM_063803508.1 → XP_063659578.1 high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A isoform X5

UniProtKB/TrEMBL

A0A2J8M8B8