GRK5 G protein-coupled receptor kinase 5 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: GRK5provided by VGNC
Official Full Name: G protein-coupled receptor kinase 5provided by VGNC
Primary source: VGNC:VGNC:4700
Locus tag: CK820_G0003835
See related: Ensembl:ENSPTRG00000002993
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 8

Exon count:: 18

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	8	NC_072406.2 (131310435..131561101)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	10	NC_072408.1 (121926108..122176034)

Chromosome 8 - NC_072406.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

SHGC-156019 (e-PCR)
- UniSTS:182317

GRK5_7795 (e-PCR)
- UniSTS:466223

RH104055 (e-PCR)
- UniSTS:98380

SHGC-149853 (e-PCR)
- UniSTS:177261

RH78041 (e-PCR)
- UniSTS:68990

STS-L15388 (e-PCR)
- UniSTS:51357

WI-19887 (e-PCR)
- UniSTS:32941

WI-4736 (e-PCR)
- UniSTS:11440

SHGC-105094 (e-PCR)
- UniSTS:169148

RH103139 (e-PCR)
- UniSTS:97473

RH69017 (e-PCR)
- UniSTS:21210

D10S478E (e-PCR)
- UniSTS:473059

D10S1271E (e-PCR)
- UniSTS:473319

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables G protein-coupled receptor kinase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of signal transduction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in signal transduction	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: G protein-coupled receptor kinase 5

XP_016774966.1

EC 2.7.1.-

EC 2.7.11.-

EC 2.7.11.16

XP_016774967.1

EC 2.7.1.-

EC 2.7.11.-

EC 2.7.11.16

XP_016774968.1

EC 2.7.1.-

EC 2.7.11.-

EC 2.7.11.16

XP_054516502.1

EC 2.7.1.-

EC 2.7.11.-

EC 2.7.11.16

XP_063638247.1

EC 2.7.1.-

EC 2.7.11.-

EC 2.7.11.16

XP_063638248.1

EC 2.7.1.-

EC 2.7.11.-

EC 2.7.11.16

XP_063638249.1

EC 2.7.1.-

EC 2.7.11.-

EC 2.7.11.16

XP_063638250.1

EC 2.7.1.-

EC 2.7.11.-

EC 2.7.11.16

XP_063638251.1

EC 2.7.1.-

EC 2.7.11.-

EC 2.7.11.16

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072406.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

131310435..131561101

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_016919477.4 → XP_016774966.1 G protein-coupled receptor kinase 5 isoform X1

UniProtKB/TrEMBL

A0A2I3TJ71, A0A2J8PC35, A0A6D2WM81, H2Q2N7, K7BG59

Related

ENSPTRP00000005279.5

Conserved Domains (2) summary

cd08752
Location:53 → 175

RGS_GRK5; Regulator of G protein signaling domain (RGS) found in G protein-coupled receptor kinase 5 (GRK5)

cd05632
Location:183 → 495

STKc_GRK5; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 5
XM_016919478.4 → XP_016774967.1 G protein-coupled receptor kinase 5 isoform X2

UniProtKB/TrEMBL

A0A2I3TJ71

Conserved Domains (2) summary

cl02565
Location:53 → 175

RGS; Regulator of G protein signaling (RGS) domain superfamily

cl21453
Location:183 → 465

PKc_like; Protein Kinases, catalytic domain
XM_016919479.4 → XP_016774968.1 G protein-coupled receptor kinase 5 isoform X3

UniProtKB/TrEMBL

A0A2I3TJ71

Conserved Domains (2) summary

cd08752
Location:21 → 143

RGS_GRK5; Regulator of G protein signaling domain (RGS) found in G protein-coupled receptor kinase 5 (GRK5)

cd05632
Location:151 → 463

STKc_GRK5; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 5
XM_063782177.1 → XP_063638247.1 G protein-coupled receptor kinase 5 isoform X4

UniProtKB/TrEMBL

A0A2I3TJ71
XM_063782180.1 → XP_063638250.1 G protein-coupled receptor kinase 5 isoform X5

UniProtKB/TrEMBL

A0A2I3RBB4, G2HI44
XM_063782181.1 → XP_063638251.1 G protein-coupled receptor kinase 5 isoform X5

UniProtKB/TrEMBL

A0A2I3RBB4, G2HI44
XM_063782179.1 → XP_063638249.1 G protein-coupled receptor kinase 5 isoform X5

UniProtKB/TrEMBL

A0A2I3RBB4, G2HI44
XM_063782178.1 → XP_063638248.1 G protein-coupled receptor kinase 5 isoform X5

UniProtKB/TrEMBL

A0A2I3RBB4, G2HI44
XM_054660527.2 → XP_054516502.1 G protein-coupled receptor kinase 5 isoform X6