TXK TXK tyrosine kinase [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: TXKprovided by VGNC
Official Full Name: TXK tyrosine kinaseprovided by VGNC
Primary source: VGNC:VGNC:3836
Locus tag: CK820_G0033386
See related: Ensembl:ENSPTRG00000016040 Ensembl:ENSPTRG00000044062
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	3	NC_072401.2 (83095204..83163245)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	4	NC_072402.1 (83095507..83165819)

Chromosome 3 - NC_072401.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

D4S3133 (e-PCR)
- UniSTS:2628

RH70607 (e-PCR)
- UniSTS:34141

SHGC-59740 (e-PCR)
- UniSTS:14949

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables non-membrane spanning protein tyrosine kinase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in T cell receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in adaptive immune response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: tyrosine-protein kinase TXK

XP_016807272.1

EC 2.7.10.1

EC 2.7.10.2

XP_063664984.1

EC 2.7.10.1

EC 2.7.10.2

XP_063664985.1

EC 2.7.10.1

EC 2.7.10.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072401.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

83095204..83163245

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_016951783.3 → XP_016807272.1 tyrosine-protein kinase TXK isoform X2

UniProtKB/TrEMBL

A0A2I3SRZ8, A0A2I3T8H3, A0A2J8L333, A0A6D2W3T5

Related

ENSPTRP00000085555.1

Conserved Domains (3) summary

cd05059
Location:266 → 521

PTKc_Tec_like; Catalytic domain of Tec-like Protein Tyrosine Kinases

cd10398
Location:143 → 248

SH2_Tec_Txk; Src homology 2 (SH2) domain found in Tec protein, Txk

cd11907
Location:85 → 139

SH3_TXK; Src Homology 3 domain of TXK, also called Resting lymphocyte kinase (Rlk)
XM_063808915.1 → XP_063664985.1 tyrosine-protein kinase TXK isoform X3

UniProtKB/TrEMBL

A0A2I3SRZ8
XM_063808914.1 → XP_063664984.1 tyrosine-protein kinase TXK isoform X1

UniProtKB/TrEMBL

A0A2I3SRZ8