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VPS8 VPS8 subunit of CORVET complex [ Pan troglodytes (chimpanzee) ]

Gene ID: 460898, updated on 6-Jun-2024

Summary

Official Symbol
VPS8provided by VGNC
Official Full Name
VPS8 subunit of CORVET complexprovided by VGNC
Primary source
VGNC:VGNC:2628
Locus tag
CK820_G0023392
See related
Ensembl:ENSPTRG00000015698
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
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Genomic context

See VPS8 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
49
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 2 NC_086015.1 (188000388..188239305)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 3 NC_072401.1 (187909754..188148676)

Chromosome 2 - NC_086015.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134809626 Neighboring gene MAGE family member F1 Neighboring gene chromosome 3 C3orf70 homolog Neighboring gene enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase Neighboring gene eukaryotic translation initiation factor 2 subunit 2-like

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in endosomal vesicle fusion IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in protein targeting to vacuole IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of CORVET complex IEA
Inferred from Electronic Annotation
more info
PubMed 
part_of HOPS complex IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in early endosome IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in late endosome IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
vacuolar protein sorting-associated protein 8 homolog
Names
VPS8, CORVET complex subunit
vacuolar protein sorting 8 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_086015.1 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    188000388..188239305
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016942447.3XP_016797936.1  vacuolar protein sorting-associated protein 8 homolog isoform X2

    UniProtKB/TrEMBL
    A0A2J8M5N0, A0A2J8M5N6, A0A2J8M5N8, A0A6D2W7S1, A0A8I3B3J6, H2QNW1, K7BNA4
    Related
    ENSPTRP00000078274.1
    Conserved Domains (4) summary
    sd00039
    Location:200237
    7WD40; WD40 repeat [structural motif]
    pfam12816
    Location:612794
    Vps8; Golgi CORVET complex core vacuolar protein 8
    cd16687
    Location:12541308
    RING-H2_Vps8; RING finger, H2 subclass, found in vacuolar protein sorting-associated protein 8 (Vps8) and similar proteins
    cl25539
    Location:195296
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  2. XM_016942443.3XP_016797932.1  vacuolar protein sorting-associated protein 8 homolog isoform X1

    UniProtKB/TrEMBL
    A0A2J8M5N0, A0A6D2W7S1, H2QNW1
  3. XM_054681298.2XP_054537273.1  vacuolar protein sorting-associated protein 8 homolog isoform X3

    UniProtKB/TrEMBL
    A0A2J8M5N0, A0A6D2W7S1, H2QNW1
  4. XM_063807397.1XP_063663467.1  vacuolar protein sorting-associated protein 8 homolog isoform X4

    UniProtKB/TrEMBL
    A0A2J8M5N0, A0A6D2W7S1, H2QNW1
  5. XM_063807400.1XP_063663470.1  vacuolar protein sorting-associated protein 8 homolog isoform X7

    UniProtKB/TrEMBL
    A0A2I3SML3, A0A2J8M5N0, A0A6D2W7S1, H2QNW1
  6. XM_063807398.1XP_063663468.1  vacuolar protein sorting-associated protein 8 homolog isoform X5

    UniProtKB/TrEMBL
    A0A2I3SML3, A0A2J8M5N0, A0A6D2W7S1, H2QNW1
  7. XM_063807399.1XP_063663469.1  vacuolar protein sorting-associated protein 8 homolog isoform X6

    UniProtKB/TrEMBL
    A0A2I3SML3, A0A2J8M5N0, A0A6D2W7S1, H2QNW1
  8. XM_063807401.1XP_063663471.1  vacuolar protein sorting-associated protein 8 homolog isoform X8

  9. XM_063807402.1XP_063663472.1  vacuolar protein sorting-associated protein 8 homolog isoform X9

  10. XM_063807396.1XP_063663466.1  vacuolar protein sorting-associated protein 8 homolog isoform X1

    UniProtKB/TrEMBL
    A0A2J8M5N0, A0A6D2W7S1, H2QNW1