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LEPR leptin receptor [ Pan troglodytes (chimpanzee) ]

Gene ID: 456919, updated on 6-Jun-2024

Summary

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Official Symbol
LEPRprovided by VGNC
Official Full Name
leptin receptorprovided by VGNC
Primary source
VGNC:VGNC:1296
Locus tag
CK820_G0010376
See related
Ensembl:ENSPTRG00000034314
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as
LEPROT
Orthologs
human mouse all
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Genomic context

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See LEPR in Genome Data Viewer
Location:
chromosome: 1
Exon count:
25
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 1 NC_072398.2 (165366803..165575874, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 1 NC_072398.1 (65727997..65932488)

Chromosome 1 - NC_072398.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112208582 Neighboring gene phosphodiesterase 4B Neighboring gene uncharacterized LOC107966997 Neighboring gene U4 spliceosomal RNA Neighboring gene uncharacterized LOC107966995 Neighboring gene polypeptide N-acetylgalactosaminyltransferase 11-like Neighboring gene small nucleolar RNA U13 Neighboring gene U2 spliceosomal RNA Neighboring gene leptin receptor overlapping transcript Neighboring gene DnaJ heat shock protein family (Hsp40) member C6 Neighboring gene uncharacterized LOC107966984

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cytokine receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
leptin receptor
Names
leptin receptor overlapping transcript

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072398.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    165366803..165575874 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001161937.6 → XP_001161937.1  leptin receptor isoform X1

    See identical proteins and their annotated locations for XP_001161937.1

    UniProtKB/TrEMBL
    A0A2J8NHG3, A0A6D2XDX6, H2RDQ7
    Conserved Domains (3) summary
    smart00060
    Location:741 → 820
    FN3; Fibronectin type 3 domain
    cd00063
    Location:237 → 330
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam06328
    Location:333 → 420
    Lep_receptor_Ig; Ig-like C2-type domain

  2. XM_016920109.4 → XP_016775598.1  leptin receptor isoform X1

    UniProtKB/TrEMBL
    A0A2J8NHG3, A0A6D2XDX6, H2RDQ7
    Conserved Domains (3) summary
    smart00060
    Location:741 → 820
    FN3; Fibronectin type 3 domain
    cd00063
    Location:237 → 330
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam06328
    Location:333 → 420
    Lep_receptor_Ig; Ig-like C2-type domain

  3. XM_009459920.5 → XP_009458195.1  leptin receptor isoform X1

    See identical proteins and their annotated locations for XP_009458195.1

    UniProtKB/TrEMBL
    A0A2J8NHG3, A0A6D2XDX6, H2RDQ7
    Related
    ENSPTRP00000059210.2
    Conserved Domains (3) summary
    smart00060
    Location:741 → 820
    FN3; Fibronectin type 3 domain
    cd00063
    Location:237 → 330
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam06328
    Location:333 → 420
    Lep_receptor_Ig; Ig-like C2-type domain

  4. XM_009459934.5 → XP_009458209.1  leptin receptor isoform X1

    See identical proteins and their annotated locations for XP_009458209.1

    UniProtKB/TrEMBL
    A0A2J8NHG3, A0A6D2XDX6, H2RDQ7
    Conserved Domains (3) summary
    smart00060
    Location:741 → 820
    FN3; Fibronectin type 3 domain
    cd00063
    Location:237 → 330
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam06328
    Location:333 → 420
    Lep_receptor_Ig; Ig-like C2-type domain

  5. XM_063800965.1 → XP_063657035.1  leptin receptor isoform X1

    UniProtKB/TrEMBL
    A0A2J8NHG3, A0A6D2XDX6, H2RDQ7

  6. XM_024346386.3 → XP_024202154.1  leptin receptor isoform X2

    UniProtKB/TrEMBL
    A0A2J8NHH3
    Conserved Domains (3) summary
    smart00060
    Location:741 → 820
    FN3; Fibronectin type 3 domain
    cd00063
    Location:237 → 330
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam06328
    Location:333 → 420
    Lep_receptor_Ig; Ig-like C2-type domain

  7. XM_001162088.7 → XP_001162088.1  leptin receptor isoform X3

    See identical proteins and their annotated locations for XP_001162088.1

    UniProtKB/TrEMBL
    A0A2J8NHG9, A0A2J8NHH3, A0A6D2XD85, K7BBI8
    Related
    ENSPTRP00000089622.1
    Conserved Domains (3) summary
    smart00060
    Location:741 → 820
    FN3; Fibronectin type 3 domain
    cd00063
    Location:237 → 330
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam06328
    Location:333 → 420
    Lep_receptor_Ig; Ig-like C2-type domain

  8. XM_063800980.1 → XP_063657050.1  leptin receptor isoform X3

    UniProtKB/TrEMBL
    A0A2J8NHG9, A0A2J8NHH3, A0A6D2XD85, K7BBI8
Nucleotide Protein
Heading Accession and Version

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