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FTO FTO alpha-ketoglutarate dependent dioxygenase [ Pan troglodytes (chimpanzee) ]

Gene ID: 454090, updated on 17-Aug-2024

Summary

Official Symbol
FTOprovided by VGNC
Official Full Name
FTO alpha-ketoglutarate dependent dioxygenaseprovided by VGNC
Primary source
VGNC:VGNC:14493
Locus tag
CK820_G0016690
See related
Ensembl:ENSPTRG00000008118
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
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Genomic context

Location:
chromosome: 18
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 18 NC_072416.2 (51655722..52059936)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 16 NC_072414.1 (51655626..52059839)

Chromosome 18 - NC_072416.2Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene RB transcriptional corepressor like 2 Neighboring gene AKT interacting protein Neighboring gene RPGRIP1 like Neighboring gene uncharacterized LOC129137341 Neighboring gene iroquois homeobox 3

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables broad specificity oxidative DNA demethylase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables ferrous iron binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables mRNA N6-methyladenosine dioxygenase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in DNA alkylation repair IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in RNA repair IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in regulation of multicellular organism growth IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
alpha-ketoglutarate-dependent dioxygenase FTO
Names
fat mass and obesity associated
XP_009429081.2
XP_016785340.2
XP_016785341.2
XP_024205605.2
XP_054524376.1
XP_054524377.1
XP_054524378.1
XP_054524379.1
XP_510968.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072416.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    51655722..52059936
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009430806.5XP_009429081.2  alpha-ketoglutarate-dependent dioxygenase FTO isoform X1

    UniProtKB/TrEMBL
    A0A2J8MWR5, A0A8I3B2R5, K7A3S8, K7D468
  2. XM_024349837.3XP_024205605.2  alpha-ketoglutarate-dependent dioxygenase FTO isoform X8

    UniProtKB/TrEMBL
    A0A2J8MWT8
  3. XM_510968.7XP_510968.3  alpha-ketoglutarate-dependent dioxygenase FTO isoform X3

    UniProtKB/TrEMBL
    A0A2J8MWR5, A0A8I3B2R5, K7A3S8, K7D468
  4. XM_054668404.2XP_054524379.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform X9

    UniProtKB/TrEMBL
    A0A2J8MWT8
  5. XM_054668402.2XP_054524377.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform X6

    UniProtKB/TrEMBL
    A0A2J8MWS3, A0A2J8MWS8, A0A6D2W2A2, H2R083
  6. XM_016929851.4XP_016785340.2  alpha-ketoglutarate-dependent dioxygenase FTO isoform X4

    UniProtKB/TrEMBL
    A0A2J8MWS3, A0A6D2W2A2, H2R083
  7. XM_054668403.2XP_054524378.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform X7

    UniProtKB/TrEMBL
    A0A2J8MWS3, A0A6D2W2A2, H2R083
  8. XM_016929852.4XP_016785341.2  alpha-ketoglutarate-dependent dioxygenase FTO isoform X5

    UniProtKB/TrEMBL
    A0A2J8MWS3, A0A6D2W2A2, H2R083
  9. XM_054668401.2XP_054524376.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform X2

    UniProtKB/TrEMBL
    A0A2J8MWR5, A0A8I3B2R5, K7A3S8, K7D468