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FTO FTO alpha-ketoglutarate dependent dioxygenase [ Homo sapiens (human) ]

Gene ID: 79068, updated on 3-Dec-2024

Summary

Official Symbol
FTOprovided by HGNC
Official Full Name
FTO alpha-ketoglutarate dependent dioxygenaseprovided by HGNC
Primary source
HGNC:HGNC:24678
See related
Ensembl:ENSG00000140718 MIM:610966; AllianceGenome:HGNC:24678
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GDFD; IFEX9; ALKBH9; BMIQ14
Summary
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011]
Expression
Ubiquitous expression in brain (RPKM 7.3), adrenal (RPKM 4.2) and 25 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See FTO in Genome Data Viewer
Location:
16q12.2
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (53703963..54121941)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (59501796..59919950)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (53737875..54155853)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105371269 Neighboring gene NANOG hESC enhancer GRCh37_chr16:53580827-53581328 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr16:53594743-53595365 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr16:53595366-53595988 Neighboring gene ReSE screen-validated silencer GRCh37_chr16:53610651-53610873 Neighboring gene NANOG hESC enhancer GRCh37_chr16:53659615-53660133 Neighboring gene RPGRIP1 like Neighboring gene VISTA enhancer hs59 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7502 Neighboring gene H3K27ac hESC enhancer GRCh37_chr16:53737766-53738266 Neighboring gene uncharacterized LOC124903691 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr16:53861530-53862207 Neighboring gene Sharpr-MPRA regulatory region 10092 Neighboring gene VISTA enhancer hs155 Neighboring gene Sharpr-MPRA regulatory region 7594 Neighboring gene VISTA enhancer hs157 Neighboring gene VISTA enhancer hs156 Neighboring gene Sharpr-MPRA regulatory region 2551 Neighboring gene uncharacterized LOC105371271 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr16:54082723-54083657 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr16:54083658-54084591 Neighboring gene FTO intronic transcript 1 Neighboring gene VISTA enhancer hs52 Neighboring gene Sharpr-MPRA regulatory region 5065 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:54228087-54228979 Neighboring gene Sharpr-MPRA regulatory region 10961 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:54318795-54319714 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:54319715-54320634 Neighboring gene long intergenic non-protein coding RNA 2169 Neighboring gene iroquois homeobox 3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Body mass index quantitative trait locus 14
MedGen: C2675914 OMIM: 612460 GeneReviews: Not available
Compare labs
Lethal polymalformative syndrome, Boissel type
MedGen: C2752001 OMIM: 612938 GeneReviews: Not available
Compare labs

EBI GWAS Catalog

Description
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity.
EBI GWAS Catalog
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.
EBI GWAS Catalog
A genome-wide association study on obesity and obesity-related traits.
EBI GWAS Catalog
A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits.
EBI GWAS Catalog
A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.
EBI GWAS Catalog
A variant in FTO shows association with melanoma risk not due to BMI.
EBI GWAS Catalog
Adiposity-related heterogeneity in patterns of type 2 diabetes susceptibility observed in genome-wide association data.
EBI GWAS Catalog
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
EBI GWAS Catalog
Common body mass index-associated variants confer risk of extreme obesity.
EBI GWAS Catalog
Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations.
EBI GWAS Catalog
Common variants near MC4R are associated with fat mass, weight and risk of obesity.
EBI GWAS Catalog
Discovery and refinement of loci associated with lipid levels.
EBI GWAS Catalog
EMR-linked GWAS study: investigation of variation landscape of loci for body mass index in children.
EBI GWAS Catalog
FTO genotype is associated with phenotypic variability of body mass index.
EBI GWAS Catalog
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile.
EBI GWAS Catalog
Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants.
EBI GWAS Catalog
Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course.
EBI GWAS Catalog
Genome-wide association analysis of body mass in chronic obstructive pulmonary disease.
EBI GWAS Catalog
Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.
EBI GWAS Catalog
Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits.
EBI GWAS Catalog
Genome-wide association studies identify four ER negative-specific breast cancer risk loci.
EBI GWAS Catalog
Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations.
EBI GWAS Catalog
Genome-wide association study for type 2 diabetes in Indians identifies a new susceptibility locus at 2q21.
EBI GWAS Catalog
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.
EBI GWAS Catalog
Genome-wide association study of circulating estradiol, testosterone, and sex hormone-binding globulin in postmenopausal women.
EBI GWAS Catalog
Genome-wide association study of height-adjusted BMI in childhood identifies functional variant in ADCY3.
EBI GWAS Catalog
Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity.
EBI GWAS Catalog
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
EBI GWAS Catalog
Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake.
EBI GWAS Catalog
Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.
EBI GWAS Catalog
Genome-wide SNP and CNV analysis identifies common and low-frequency variants associated with severe early-onset obesity.
EBI GWAS Catalog
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
EBI GWAS Catalog
Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.
EBI GWAS Catalog
Integrated Genome-wide Association, Coexpression Network, and Expression Single Nucleotide Polymorphism Analysis Identifies Novel Pathway in Allergic Rhinitis.
EBI GWAS Catalog
Large-scale genotyping identifies 41 new loci associated with breast cancer risk.
EBI GWAS Catalog
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.
EBI GWAS Catalog
Meta-analysis of genome-wide association data identifies novel susceptibility loci for obesity.
EBI GWAS Catalog
Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index.
EBI GWAS Catalog
NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium.
EBI GWAS Catalog
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.
EBI GWAS Catalog
Replication of 13 obesity loci among Singaporean Chinese, Malay and Asian-Indian populations.
EBI GWAS Catalog
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.
EBI GWAS Catalog
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation.
EBI GWAS Catalog
Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases.
EBI GWAS Catalog
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies.
EBI GWAS Catalog
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.
EBI GWAS Catalog
Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups.
EBI GWAS Catalog

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC5149, KIAA1752

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables broad specificity oxidative DNA demethylase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables broad specificity oxidative DNA demethylase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables ferrous iron binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ferrous iron binding IDA
Inferred from Direct Assay
more info
PubMed 
enables mRNA N6-methyladenosine dioxygenase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables mRNA N6-methyladenosine dioxygenase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables mRNA N6-methyladenosine dioxygenase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables oxidative RNA demethylase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables tRNA demethylase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in DNA alkylation repair IDA
Inferred from Direct Assay
more info
PubMed 
involved_in RNA repair IDA
Inferred from Direct Assay
more info
PubMed 
involved_in adipose tissue development IEA
Inferred from Electronic Annotation
more info
 
involved_in mRNA destabilization IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of brown fat cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of lipid storage IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of multicellular organism growth IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of respiratory system process IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of white fat cell proliferation IEA
Inferred from Electronic Annotation
more info
 
involved_in snRNA processing IDA
Inferred from Direct Assay
more info
PubMed 
involved_in temperature homeostasis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
 
located_in intracellular membrane-bounded organelle IDA
Inferred from Direct Assay
more info
 
located_in nuclear speck IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleoplasm TAS
Traceable Author Statement
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
alpha-ketoglutarate-dependent dioxygenase FTO
Names
AlkB homolog 9
U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO
U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO
fat mass and obesity associated
fat mass and obesity-associated protein
intragenic FTO exon 9 containing transcript
m6A(m)-demethylase FTO
mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO
mRNA N(6)-methyladenosine demethylase FTO
tRNA N1-methyl adenine demethylase FTO
NP_001073901.1
NP_001350820.1
NP_001350823.1
NP_001350825.1
NP_001350826.1
NP_001350827.1
NP_001350828.1
NP_001350829.1
NP_001350830.1
NP_001350832.1
NP_001350834.1
NP_001350917.1
XP_011521616.1
XP_011521617.1
XP_011521618.1
XP_016879143.1
XP_016879145.1
XP_016879146.1
XP_024306205.1
XP_047290562.1
XP_047290563.1
XP_047290564.1
XP_047290565.1
XP_054169858.1
XP_054169859.1
XP_054169860.1
XP_054169861.1
XP_054169862.1
XP_054169863.1
XP_054169864.1
XP_054169865.1
XP_054169866.1
XP_054169867.1
XP_054169868.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_012969.2 RefSeqGene

    Range
    5195..422980
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001080432.3NP_001073901.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform 3

    See identical proteins and their annotated locations for NP_001073901.1

    Status: REVIEWED

    Source sequence(s)
    AB051539, AC007347, AK096554, BC001284, BC030798, DA324897, U79260
    Consensus CDS
    CCDS32448.1
    UniProtKB/Swiss-Prot
    A2RUH1, B2RNS0, Q0P676, Q7Z785, Q9C0B1
    UniProtKB/TrEMBL
    B3KU60
    Related
    ENSP00000418823.1, ENST00000471389.6
    Conserved Domains (2) summary
    pfam12933
    Location:40324
    FTO_NTD; FTO catalytic domain
    pfam12934
    Location:329498
    FTO_CTD; FTO C-terminal domain
  2. NM_001363891.1NP_001350820.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC007347, AC007496, AC007909
    UniProtKB/TrEMBL
    B3KU60
    Related
    ENSP00000490516.1, ENST00000637969.1
    Conserved Domains (2) summary
    pfam12933
    Location:40334
    FTO_NTD; FTO catalytic domain
    pfam12934
    Location:339508
    FTO_CTD; FTO C-terminal domain
  3. NM_001363894.1NP_001350823.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC007347, AC007496, AC007909
    UniProtKB/TrEMBL
    B3KU60
    Conserved Domains (2) summary
    pfam12933
    Location:36325
    FTO_NTD; FTO catalytic domain
    pfam12934
    Location:329519
    FTO_CTD; FTO C-terminal domain
  4. NM_001363896.1NP_001350825.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform 4

    Status: REVIEWED

    Source sequence(s)
    AC007347, AC007496, AC007909
    UniProtKB/TrEMBL
    B3KU60
    Conserved Domains (2) summary
    pfam12933
    Location:36325
    FTO_NTD; FTO catalytic domain
    pfam12934
    Location:329492
    FTO_CTD; FTO C-terminal domain
  5. NM_001363897.1NP_001350826.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC007347, AC007496, AC007909
    UniProtKB/TrEMBL
    B3KU60
    Conserved Domains (2) summary
    pfam12933
    Location:16299
    FTO_NTD; FTO catalytic domain
    pfam12934
    Location:303472
    FTO_CTD; FTO C-terminal domain
  6. NM_001363898.1NP_001350827.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform 6

    Status: REVIEWED

    Source sequence(s)
    AC007347, AC007496, AC007909
    UniProtKB/TrEMBL
    B3KU60
    Conserved Domains (2) summary
    pfam12933
    Location:36335
    FTO_NTD; FTO catalytic domain
    pfam12934
    Location:330460
    FTO_CTD; FTO C-terminal domain
  7. NM_001363899.1NP_001350828.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform 7

    Status: REVIEWED

    Source sequence(s)
    AC007347, AC007496, AC007909
    UniProtKB/TrEMBL
    B3KU60
    Conserved Domains (2) summary
    pfam12933
    Location:36287
    FTO_NTD; FTO catalytic domain
    pfam12934
    Location:291460
    FTO_CTD; FTO C-terminal domain
  8. NM_001363900.1NP_001350829.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform 8

    Status: REVIEWED

    Source sequence(s)
    AC007347, AC007496, AC007909
    UniProtKB/TrEMBL
    B3KU60
    Conserved Domains (2) summary
    pfam12933
    Location:36325
    FTO_NTD; FTO catalytic domain
    pfam12934
    Location:320450
    FTO_CTD; FTO C-terminal domain
  9. NM_001363901.1NP_001350830.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform 9

    Status: REVIEWED

    Source sequence(s)
    AC007347, AC007496, AC007909
    UniProtKB/TrEMBL
    B3KU60
    Conserved Domains (2) summary
    pfam12933
    Location:36277
    FTO_NTD; FTO catalytic domain
    pfam12934
    Location:281450
    FTO_CTD; FTO C-terminal domain
  10. NM_001363903.1NP_001350832.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform 10

    Status: REVIEWED

    Source sequence(s)
    AC007347, AC007496, AC007909
    UniProtKB/TrEMBL
    A0A1B0GTY1
    Related
    ENSP00000489886.1, ENST00000636992.1
    Conserved Domains (2) summary
    pfam12933
    Location:36325
    FTO_NTD; FTO catalytic domain
    pfam12934
    Location:329411
    FTO_CTD; FTO C-terminal domain
  11. NM_001363905.1NP_001350834.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform 11

    Status: REVIEWED

    Source sequence(s)
    AC007347, AC007496, AC007909
    Conserved Domains (2) summary
    pfam12933
    Location:21154
    FTO_NTD; FTO catalytic domain
    pfam12934
    Location:158327
    FTO_CTD; FTO C-terminal domain
  12. NM_001363988.1NP_001350917.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform 12

    Status: REVIEWED

    Source sequence(s)
    AC007347, AC007496, AC007909
    UniProtKB/TrEMBL
    A0A1B0GV98
    Conserved Domains (2) summary
    pfam12933
    Location:36325
    FTO_NTD; FTO catalytic domain
    pfam12934
    Location:329455
    FTO_CTD; FTO C-terminal domain

RNA

  1. NR_156761.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC007347, AC007496, AC007909

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    53703963..54121941
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047434606.1XP_047290562.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform X2

    UniProtKB/TrEMBL
    A0A1B0GV98
  2. XM_047434607.1XP_047290563.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform X3

    UniProtKB/TrEMBL
    A0A1B0GV98
  3. XM_011523314.4XP_011521616.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform X4

    UniProtKB/TrEMBL
    A0A1B0GV98
    Conserved Domains (2) summary
    pfam12933
    Location:36335
    FTO_NTD; FTO catalytic domain
    pfam12934
    Location:339465
    FTO_CTD; FTO C-terminal domain
  4. XM_011523316.4XP_011521618.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform X6

    UniProtKB/TrEMBL
    A0A1B0GV98
    Conserved Domains (2) summary
    pfam12933
    Location:36335
    FTO_NTD; FTO catalytic domain
    pfam12934
    Location:339464
    FTO_CTD; FTO C-terminal domain
  5. XM_017023656.3XP_016879145.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform X7

    UniProtKB/TrEMBL
    A0A1B0GV98
  6. XM_024450437.2XP_024306205.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform X9

    UniProtKB/TrEMBL
    A0A1B0GV98
    Conserved Domains (2) summary
    pfam12933
    Location:36325
    FTO_NTD; FTO catalytic domain
    pfam12934
    Location:329454
    FTO_CTD; FTO C-terminal domain
  7. XM_017023654.3XP_016879143.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform X1

    UniProtKB/TrEMBL
    A0A1B0GV98
    Related
    ENST00000636030.1
  8. XM_011523315.4XP_011521617.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform X5

    UniProtKB/TrEMBL
    A0A1B0GV98
    Conserved Domains (2) summary
    pfam12933
    Location:36335
    FTO_NTD; FTO catalytic domain
    pfam12934
    Location:339465
    FTO_CTD; FTO C-terminal domain
  9. XM_047434608.1XP_047290564.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform X5

    UniProtKB/TrEMBL
    A0A1B0GV98
  10. XM_017023657.3XP_016879146.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform X8

    UniProtKB/TrEMBL
    A0A1B0GTC5, A0A1B0GV98
    Related
    ENSP00000489641.1, ENST00000636218.1
  11. XM_047434609.1XP_047290565.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform X8

    UniProtKB/TrEMBL
    A0A1B0GTC5, A0A1B0GV98
    Related
    ENSP00000489936.1, ENST00000637001.1

RNA

  1. XR_007064911.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060940.1 Alternate T2T-CHM13v2.0

    Range
    59501796..59919950
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054313884.1XP_054169859.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform X2

    UniProtKB/TrEMBL
    A0A1B0GV98
  2. XM_054313885.1XP_054169860.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform X3

    UniProtKB/TrEMBL
    A0A1B0GV98
  3. XM_054313886.1XP_054169861.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform X4

    UniProtKB/TrEMBL
    A0A1B0GV98
  4. XM_054313889.1XP_054169864.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform X6

    UniProtKB/TrEMBL
    A0A1B0GV98
  5. XM_054313890.1XP_054169865.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform X7

    UniProtKB/TrEMBL
    A0A1B0GV98
  6. XM_054313893.1XP_054169868.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform X9

    UniProtKB/TrEMBL
    A0A1B0GV98
  7. XM_054313883.1XP_054169858.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform X1

    UniProtKB/TrEMBL
    A0A1B0GV98
  8. XM_054313887.1XP_054169862.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform X5

    UniProtKB/TrEMBL
    A0A1B0GV98
  9. XM_054313888.1XP_054169863.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform X5

    UniProtKB/TrEMBL
    A0A1B0GV98
  10. XM_054313891.1XP_054169866.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform X8

    UniProtKB/TrEMBL
    A0A1B0GTC5, A0A1B0GV98
  11. XM_054313892.1XP_054169867.1  alpha-ketoglutarate-dependent dioxygenase FTO isoform X8

    UniProtKB/TrEMBL
    A0A1B0GTC5, A0A1B0GV98

RNA

  1. XR_008484736.1 RNA Sequence