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FERMT3 FERM domain containing kindlin 3 [ Pan troglodytes (chimpanzee) ]

Gene ID: 451287, updated on 6-Jun-2024

Summary

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Official Symbol
FERMT3provided by VGNC
Official Full Name
FERM domain containing kindlin 3provided by VGNC
Primary source
VGNC:VGNC:1053
Locus tag
CK820_G0034043
See related
Ensembl:ENSPTRG00000024042
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as
URP2
Orthologs
human mouse all
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Genomic context

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See FERMT3 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 9 NC_072407.2 (66519842..66538953)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 11 NC_072409.1 (65629449..65649760)

Chromosome 9 - NC_072407.2Genomic Context describing neighboring genes Neighboring gene mono-ADP ribosylhydrolase 1 Neighboring gene fibronectin leucine rich transmembrane protein 1 Neighboring gene stress induced phosphoprotein 1 Neighboring gene nudix hydrolase 22 Neighboring gene tRNA phosphotransferase 1 Neighboring gene DnaJ heat shock protein family (Hsp40) member C4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in integrin activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in leukocyte cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in platelet aggregation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell-cell adhesion mediated by integrin IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell-substrate junction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
fermitin family homolog 3
Names
UNC-112 related protein 2
fermitin family member 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072407.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    66519842..66538953
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_508522.8 → XP_508522.3  fermitin family homolog 3 isoform X4

    See identical proteins and their annotated locations for XP_508522.3

    UniProtKB/TrEMBL
    A0A2J8QCZ3, A0A6D2Y309, H2R0U2, K7CXZ4
    Conserved Domains (6) summary
    smart00295
    Location:218 → 315
    B41; Band 4.1 homologues
    cd01237
    Location:350 → 474
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:548 → 639
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17182
    Location:15 → 97
    FERM_F0_KIND3; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in kindlin-3 (KIND3)
    cd17185
    Location:98 → 254
    FERM_F1_KIND3; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-3 (KIND3)
    pfam00373
    Location:463 → 553
    FERM_M; FERM central domain

  2. XM_009423350.5 → XP_009421625.1  fermitin family homolog 3 isoform X4

    See identical proteins and their annotated locations for XP_009421625.1

    UniProtKB/TrEMBL
    A0A2J8QCZ3, A0A6D2Y309, H2R0U2, K7CXZ4
    Related
    ENSPTRP00000041266.5
    Conserved Domains (6) summary
    smart00295
    Location:218 → 315
    B41; Band 4.1 homologues
    cd01237
    Location:350 → 474
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:548 → 639
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17182
    Location:15 → 97
    FERM_F0_KIND3; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in kindlin-3 (KIND3)
    cd17185
    Location:98 → 254
    FERM_F1_KIND3; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-3 (KIND3)
    pfam00373
    Location:463 → 553
    FERM_M; FERM central domain

  3. XM_063782998.1 → XP_063639068.1  fermitin family homolog 3 isoform X3

    UniProtKB/TrEMBL
    H2R0U2

  4. XM_063782999.1 → XP_063639069.1  fermitin family homolog 3 isoform X3

    UniProtKB/TrEMBL
    H2R0U2

  5. XM_063783000.1 → XP_063639070.1  fermitin family homolog 3 isoform X5

  6. XM_063782997.1 → XP_063639067.1  fermitin family homolog 3 isoform X1

    UniProtKB/TrEMBL
    A0A2J8QD08

  7. XM_054662386.2 → XP_054518361.1  fermitin family homolog 3 isoform X2

    UniProtKB/TrEMBL
    A0A2J8QD08
Nucleotide Protein
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