SLC12A2 solute carrier family 12 member 2 [Gallus gallus (chicken)] - Gene

Summary

Symbol: SLC12A2provided by CGNC
Full Name: solute carrier family 12 member 2provided by CGNC
Primary source: CGNC:10891
See related: Ensembl:ENSGALG00010012969
Gene type: protein coding
RefSeq status: MODEL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: Z

Exon count:: 27

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	Z	NC_052572.1 (57500796..57555527)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	Z	NC_059536.1 (57500796..57555527)

Chromosome Z - NC_052572.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ammonium channel activity	IEA Inferred from Electronic Annotation more info	PubMed
enables sodium:potassium:chloride symporter activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell volume homeostasis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in chloride ion homeostasis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in chloride transmembrane transport	IEA Inferred from Electronic Annotation more info	PubMed
involved_in potassium ion homeostasis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in potassium ion import across plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed
involved_in sodium ion homeostasis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in sodium ion transmembrane transport	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: solute carrier family 12 member 2

Names: solute carrier family 12 (sodium/potassium/chloride transporter), member 2; solute carrier family 12 (sodium/potassium/chloride transporters), member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052572.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

57500796..57555527

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_003643059.6 → XP_003643107.1 solute carrier family 12 member 2 isoform X1

UniProtKB/TrEMBL

A0A8V0YJV8, F1NR57

Related

ENSGALP00010018118.1, ENSGALT00010031124.1

Conserved Domains (4) summary

TIGR00930
Location:150 → 1150

2a30; K-Cl cotransporter

pfam03522
Location:734 → 1150

SLC12; Solute carrier family 12

pfam08403
Location:136 → 197

AA_permease_N; Amino acid permease N-terminal

cl00456
Location:242 → 676

SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
XM_004949378.5 → XP_004949435.1 solute carrier family 12 member 2 isoform X3

UniProtKB/TrEMBL

A0A1D5PPU2, A0A8V0YJV8

Related

ENSGALP00010018114.1, ENSGALT00010031120.1

Conserved Domains (4) summary

TIGR00930
Location:150 → 1134

2a30; K-Cl cotransporter

pfam03522
Location:734 → 1134

SLC12; Solute carrier family 12

pfam08403
Location:136 → 197

AA_permease_N; Amino acid permease N-terminal

cl00456
Location:242 → 676

SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
XM_004949377.5 → XP_004949434.1 solute carrier family 12 member 2 isoform X2

UniProtKB/TrEMBL

A0A8V0YJV8

Conserved Domains (4) summary

TIGR00930
Location:150 → 1149

2a30; K-Cl cotransporter

pfam03522
Location:734 → 1149

SLC12; Solute carrier family 12

pfam08403
Location:136 → 197

AA_permease_N; Amino acid permease N-terminal

cl00456
Location:242 → 676

SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
XM_040655729.2 → XP_040511663.1 solute carrier family 12 member 2 isoform X4

UniProtKB/TrEMBL

A0A8V0YJV8

Conserved Domains (1) summary

TIGR00930
Location:150 → 1133

2a30; K-Cl cotransporter

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_059536.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

57500796..57555527

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_046936914.1 → XP_046792870.1 solute carrier family 12 member 2 isoform X1

UniProtKB/TrEMBL

A0A8V0YJV8, F1NR57
XM_046936916.1 → XP_046792872.1 solute carrier family 12 member 2 isoform X3

UniProtKB/TrEMBL

A0A1D5PPU2, A0A8V0YJV8
XM_046936915.1 → XP_046792871.1 solute carrier family 12 member 2 isoform X2

UniProtKB/TrEMBL

A0A8V0YJV8
XM_046936917.1 → XP_046792873.1 solute carrier family 12 member 2 isoform X4

UniProtKB/TrEMBL

A0A8V0YJV8