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HCLS1 hematopoietic cell-specific Lyn substrate 1 [ Gallus gallus (chicken) ]

Gene ID: 426867, updated on 17-Aug-2024

Summary

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Symbol
HCLS1provided by CGNC
Full Name
hematopoietic cell-specific Lyn substrate 1provided by CGNC
Primary source
CGNC:7430
See related
Ensembl:ENSGALG00010007408
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
16
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (495336..507494)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (605679..617881)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121113363 Neighboring gene guanylyl cyclase-activating protein 1-like Neighboring gene golgin B1 Neighboring gene olfactory receptor, family 9, subfamily Q, member 1 Neighboring gene NME/NM23 nucleoside diphosphate kinase 6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of actin filament polymerization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in actin filament IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cortical actin cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in site of polarized growth IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hematopoietic lineage cell-specific protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001031401.2 → NP_001026572.1  hematopoietic lineage cell-specific protein

    See identical proteins and their annotated locations for NP_001026572.1

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000004
    UniProtKB/TrEMBL
    A0A8V0XXK6, F1NVS5, Q5ZMV0
    Related
    ENSGALP00010009760.1, ENSGALT00010017660.1
    Conserved Domains (2) summary
    cd12073
    Location:460 → 514
    SH3_HS1; Src homology 3 domain of Hematopoietic lineage cell-specific protein 1
    pfam02218
    Location:193 → 228
    HS1_rep; Repeat in HS1/Cortactin

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    495336..507494
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040701184.2 → XP_040557118.1  hematopoietic lineage cell-specific protein isoform X3

    UniProtKB/TrEMBL
    A0A8V0XXK6, F1NVS5, Q5ZMV0
    Conserved Domains (2) summary
    cd12073
    Location:460 → 514
    SH3_HS1; Src homology 3 domain of Hematopoietic lineage cell-specific protein 1
    pfam02218
    Location:193 → 228
    HS1_rep; Repeat in HS1/Cortactin

  2. XM_046942738.1 → XP_046798694.1  hematopoietic lineage cell-specific protein isoform X1

    UniProtKB/TrEMBL
    A0A8V0XST8, A0A8V0XXK6
    Related
    ENSGALP00010009761.1, ENSGALT00010017661.1

  3. XM_040701182.2 → XP_040557116.1  hematopoietic lineage cell-specific protein isoform X2

    UniProtKB/TrEMBL
    A0A8V0XXK6
    Conserved Domains (2) summary
    cd12073
    Location:462 → 516
    SH3_HS1; Src homology 3 domain of Hematopoietic lineage cell-specific protein 1
    pfam02218
    Location:196 → 231
    HS1_rep; Repeat in HS1/Cortactin

  4. XM_040701186.2 → XP_040557120.1  hematopoietic lineage cell-specific protein isoform X4

    UniProtKB/TrEMBL
    A0A8V0XXK6
    Conserved Domains (1) summary
    cd12073
    Location:459 → 513
    SH3_HS1; Src homology 3 domain of Hematopoietic lineage cell-specific protein 1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    605679..617881
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046908533.1 → XP_046764489.1  hematopoietic lineage cell-specific protein isoform X1

    UniProtKB/TrEMBL
    A0A8V0XST8, A0A8V0XXK6

  2. XM_046908534.1 → XP_046764490.1  hematopoietic lineage cell-specific protein isoform X2

    UniProtKB/TrEMBL
    A0A8V0XXK6

  3. XM_046908537.1 → XP_046764493.1  hematopoietic lineage cell-specific protein isoform X4

    UniProtKB/TrEMBL
    A0A8V0XXK6

  4. XM_046908536.1 → XP_046764492.1  hematopoietic lineage cell-specific protein isoform X3

    UniProtKB/TrEMBL
    A0A8V0XXK6, F1NVS5, Q5ZMV0
Nucleotide Protein Strain
Heading Accession and Version

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