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MBD5 methyl-CpG binding domain protein 5 [ Gallus gallus (chicken) ]

Gene ID: 424308, updated on 17-Aug-2024

Summary

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Symbol
MBD5provided by CGNC
Full Name
methyl-CpG binding domain protein 5provided by CGNC
Primary source
CGNC:52170
See related
Ensembl:ENSGALG00010009515
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See MBD5 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
16
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 7 NC_052538.1 (34182874..34310184)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 7 NC_052579.1 (34100509..34227967)

Chromosome 7 - NC_052538.1Genomic Context describing neighboring genes Neighboring gene U1 spliceosomal RNA Neighboring gene activin A receptor type 2A Neighboring gene origin recognition complex subunit 4 Neighboring gene uncharacterized LOC107053851 Neighboring gene uncharacterized LOC121111345 Neighboring gene uncharacterized LOC121111347 Neighboring gene enhancer of polycomb homolog 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables chromatin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in chromocenter IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
methyl-CpG-binding domain protein 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052538.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    34182874..34310184
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046944160.1 → XP_046800116.1  methyl-CpG-binding domain protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y461, A0A8V0YB25

  2. XM_040704375.2 → XP_040560309.1  methyl-CpG-binding domain protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y461, A0A8V0YB25
    Conserved Domains (2) summary
    cd05835
    Location:1624 → 1714
    Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
    cl00110
    Location:16 → 79
    MBD; MeCP2, MBD1, MBD2, MBD3, MBD4, CLLD8-like, and BAZ2A-like proteins constitute a family of proteins that share the methyl-CpG-binding domain (MBD). The MBD consists of about 70 residues and is defined as the minimal region required for binding to ...

  3. XM_040704374.2 → XP_040560308.1  methyl-CpG-binding domain protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y461, A0A8V0YB25
    Conserved Domains (2) summary
    cd05835
    Location:1624 → 1714
    Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
    cl00110
    Location:16 → 79
    MBD; MeCP2, MBD1, MBD2, MBD3, MBD4, CLLD8-like, and BAZ2A-like proteins constitute a family of proteins that share the methyl-CpG-binding domain (MBD). The MBD consists of about 70 residues and is defined as the minimal region required for binding to ...

  4. XM_004943022.5 → XP_004943079.2  methyl-CpG-binding domain protein 5 isoform X2

    UniProtKB/TrEMBL
    A0A8V0Y461
    Conserved Domains (2) summary
    cl00110
    Location:16 → 79
    MBD; MeCP2, MBD1, MBD2, MBD3, MBD4, CLLD8-like, and BAZ2A-like proteins constitute a family of proteins that share the methyl-CpG-binding domain (MBD). The MBD consists of about 70 residues and is defined as the minimal region required for binding to ...
    cl02554
    Location:1624 → 1701
    PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...

  5. XM_015289885.4 → XP_015145371.2  methyl-CpG-binding domain protein 5 isoform X3

    UniProtKB/TrEMBL
    A0A8V0Y461
    Conserved Domains (2) summary
    cd05835
    Location:1390 → 1480
    Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
    cl00110
    Location:16 → 79
    MBD; MeCP2, MBD1, MBD2, MBD3, MBD4, CLLD8-like, and BAZ2A-like proteins constitute a family of proteins that share the methyl-CpG-binding domain (MBD). The MBD consists of about 70 residues and is defined as the minimal region required for binding to ...

  6. XM_422153.8 → XP_422153.3  methyl-CpG-binding domain protein 5 isoform X4

    UniProtKB/TrEMBL
    A0A8V0Y461
    Conserved Domains (2) summary
    cl00110
    Location:16 → 79
    MBD; MeCP2, MBD1, MBD2, MBD3, MBD4, CLLD8-like, and BAZ2A-like proteins constitute a family of proteins that share the methyl-CpG-binding domain (MBD). The MBD consists of about 70 residues and is defined as the minimal region required for binding to ...
    cl02554
    Location:1390 → 1467
    PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...

  7. XM_015289877.4 → XP_015145363.2  methyl-CpG-binding domain protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y461, A0A8V0YB25
    Conserved Domains (2) summary
    cd05835
    Location:1624 → 1714
    Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
    cl00110
    Location:16 → 79
    MBD; MeCP2, MBD1, MBD2, MBD3, MBD4, CLLD8-like, and BAZ2A-like proteins constitute a family of proteins that share the methyl-CpG-binding domain (MBD). The MBD consists of about 70 residues and is defined as the minimal region required for binding to ...

  8. XM_015289881.4 → XP_015145367.2  methyl-CpG-binding domain protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y461, A0A8V0YB25
    Conserved Domains (2) summary
    cd05835
    Location:1624 → 1714
    Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
    cl00110
    Location:16 → 79
    MBD; MeCP2, MBD1, MBD2, MBD3, MBD4, CLLD8-like, and BAZ2A-like proteins constitute a family of proteins that share the methyl-CpG-binding domain (MBD). The MBD consists of about 70 residues and is defined as the minimal region required for binding to ...

  9. XM_015289878.4 → XP_015145364.2  methyl-CpG-binding domain protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y461, A0A8V0YB25
    Conserved Domains (2) summary
    cd05835
    Location:1624 → 1714
    Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
    cl00110
    Location:16 → 79
    MBD; MeCP2, MBD1, MBD2, MBD3, MBD4, CLLD8-like, and BAZ2A-like proteins constitute a family of proteins that share the methyl-CpG-binding domain (MBD). The MBD consists of about 70 residues and is defined as the minimal region required for binding to ...

  10. XM_015289882.4 → XP_015145368.2  methyl-CpG-binding domain protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y461, A0A8V0YB25
    Conserved Domains (2) summary
    cd05835
    Location:1624 → 1714
    Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
    cl00110
    Location:16 → 79
    MBD; MeCP2, MBD1, MBD2, MBD3, MBD4, CLLD8-like, and BAZ2A-like proteins constitute a family of proteins that share the methyl-CpG-binding domain (MBD). The MBD consists of about 70 residues and is defined as the minimal region required for binding to ...

  11. XM_046944159.1 → XP_046800115.1  methyl-CpG-binding domain protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y461, A0A8V0YB25
    Related
    ENSGALP00010013130.1, ENSGALT00010022722.1

  12. XM_040704376.2 → XP_040560310.1  methyl-CpG-binding domain protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y461, A0A8V0YB25
    Conserved Domains (2) summary
    cd05835
    Location:1624 → 1714
    Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
    cl00110
    Location:16 → 79
    MBD; MeCP2, MBD1, MBD2, MBD3, MBD4, CLLD8-like, and BAZ2A-like proteins constitute a family of proteins that share the methyl-CpG-binding domain (MBD). The MBD consists of about 70 residues and is defined as the minimal region required for binding to ...

  13. XM_025152451.3 → XP_025008219.2  methyl-CpG-binding domain protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y461, A0A8V0YB25
    Conserved Domains (2) summary
    cd05835
    Location:1624 → 1714
    Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
    cl00110
    Location:16 → 79
    MBD; MeCP2, MBD1, MBD2, MBD3, MBD4, CLLD8-like, and BAZ2A-like proteins constitute a family of proteins that share the methyl-CpG-binding domain (MBD). The MBD consists of about 70 residues and is defined as the minimal region required for binding to ...

  14. XM_025152452.3 → XP_025008220.2  methyl-CpG-binding domain protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y461, A0A8V0YB25
    Conserved Domains (2) summary
    cd05835
    Location:1624 → 1714
    Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
    cl00110
    Location:16 → 79
    MBD; MeCP2, MBD1, MBD2, MBD3, MBD4, CLLD8-like, and BAZ2A-like proteins constitute a family of proteins that share the methyl-CpG-binding domain (MBD). The MBD consists of about 70 residues and is defined as the minimal region required for binding to ...

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052579.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    34100509..34227967
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046921687.1 → XP_046777643.1  methyl-CpG-binding domain protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y461, A0A8V0YB25

  2. XM_040677038.2 → XP_040532972.1  methyl-CpG-binding domain protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y461, A0A8V0YB25
    Conserved Domains (2) summary
    cd05835
    Location:1624 → 1714
    Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
    cl00110
    Location:16 → 79
    MBD; MeCP2, MBD1, MBD2, MBD3, MBD4, CLLD8-like, and BAZ2A-like proteins constitute a family of proteins that share the methyl-CpG-binding domain (MBD). The MBD consists of about 70 residues and is defined as the minimal region required for binding to ...

  3. XM_040677034.2 → XP_040532968.1  methyl-CpG-binding domain protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y461, A0A8V0YB25
    Conserved Domains (2) summary
    cd05835
    Location:1624 → 1714
    Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
    cl00110
    Location:16 → 79
    MBD; MeCP2, MBD1, MBD2, MBD3, MBD4, CLLD8-like, and BAZ2A-like proteins constitute a family of proteins that share the methyl-CpG-binding domain (MBD). The MBD consists of about 70 residues and is defined as the minimal region required for binding to ...

  4. XM_040677044.2 → XP_040532978.1  methyl-CpG-binding domain protein 5 isoform X2

    UniProtKB/TrEMBL
    A0A8V0Y461
    Conserved Domains (2) summary
    cl00110
    Location:16 → 79
    MBD; MeCP2, MBD1, MBD2, MBD3, MBD4, CLLD8-like, and BAZ2A-like proteins constitute a family of proteins that share the methyl-CpG-binding domain (MBD). The MBD consists of about 70 residues and is defined as the minimal region required for binding to ...
    cl02554
    Location:1624 → 1701
    PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...

  5. XM_040677045.2 → XP_040532979.1  methyl-CpG-binding domain protein 5 isoform X3

    UniProtKB/TrEMBL
    A0A8V0Y461
    Conserved Domains (2) summary
    cd05835
    Location:1390 → 1480
    Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
    cl00110
    Location:16 → 79
    MBD; MeCP2, MBD1, MBD2, MBD3, MBD4, CLLD8-like, and BAZ2A-like proteins constitute a family of proteins that share the methyl-CpG-binding domain (MBD). The MBD consists of about 70 residues and is defined as the minimal region required for binding to ...

  6. XM_040677046.2 → XP_040532980.1  methyl-CpG-binding domain protein 5 isoform X4

    UniProtKB/TrEMBL
    A0A8V0Y461
    Conserved Domains (2) summary
    cl00110
    Location:16 → 79
    MBD; MeCP2, MBD1, MBD2, MBD3, MBD4, CLLD8-like, and BAZ2A-like proteins constitute a family of proteins that share the methyl-CpG-binding domain (MBD). The MBD consists of about 70 residues and is defined as the minimal region required for binding to ...
    cl02554
    Location:1390 → 1467
    PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...

  7. XM_040677039.2 → XP_040532973.1  methyl-CpG-binding domain protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y461, A0A8V0YB25
    Conserved Domains (2) summary
    cd05835
    Location:1624 → 1714
    Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
    cl00110
    Location:16 → 79
    MBD; MeCP2, MBD1, MBD2, MBD3, MBD4, CLLD8-like, and BAZ2A-like proteins constitute a family of proteins that share the methyl-CpG-binding domain (MBD). The MBD consists of about 70 residues and is defined as the minimal region required for binding to ...

  8. XM_040677040.2 → XP_040532974.1  methyl-CpG-binding domain protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y461, A0A8V0YB25
    Conserved Domains (2) summary
    cd05835
    Location:1624 → 1714
    Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
    cl00110
    Location:16 → 79
    MBD; MeCP2, MBD1, MBD2, MBD3, MBD4, CLLD8-like, and BAZ2A-like proteins constitute a family of proteins that share the methyl-CpG-binding domain (MBD). The MBD consists of about 70 residues and is defined as the minimal region required for binding to ...

  9. XM_040677036.2 → XP_040532970.1  methyl-CpG-binding domain protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y461, A0A8V0YB25
    Conserved Domains (2) summary
    cd05835
    Location:1624 → 1714
    Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
    cl00110
    Location:16 → 79
    MBD; MeCP2, MBD1, MBD2, MBD3, MBD4, CLLD8-like, and BAZ2A-like proteins constitute a family of proteins that share the methyl-CpG-binding domain (MBD). The MBD consists of about 70 residues and is defined as the minimal region required for binding to ...

  10. XM_040677041.2 → XP_040532975.1  methyl-CpG-binding domain protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y461, A0A8V0YB25
    Conserved Domains (2) summary
    cd05835
    Location:1624 → 1714
    Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
    cl00110
    Location:16 → 79
    MBD; MeCP2, MBD1, MBD2, MBD3, MBD4, CLLD8-like, and BAZ2A-like proteins constitute a family of proteins that share the methyl-CpG-binding domain (MBD). The MBD consists of about 70 residues and is defined as the minimal region required for binding to ...

  11. XM_046921686.1 → XP_046777642.1  methyl-CpG-binding domain protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y461, A0A8V0YB25

  12. XM_040677042.2 → XP_040532976.1  methyl-CpG-binding domain protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y461, A0A8V0YB25
    Conserved Domains (2) summary
    cd05835
    Location:1624 → 1714
    Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
    cl00110
    Location:16 → 79
    MBD; MeCP2, MBD1, MBD2, MBD3, MBD4, CLLD8-like, and BAZ2A-like proteins constitute a family of proteins that share the methyl-CpG-binding domain (MBD). The MBD consists of about 70 residues and is defined as the minimal region required for binding to ...

  13. XM_040677037.2 → XP_040532971.1  methyl-CpG-binding domain protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y461, A0A8V0YB25
    Conserved Domains (2) summary
    cd05835
    Location:1624 → 1714
    Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
    cl00110
    Location:16 → 79
    MBD; MeCP2, MBD1, MBD2, MBD3, MBD4, CLLD8-like, and BAZ2A-like proteins constitute a family of proteins that share the methyl-CpG-binding domain (MBD). The MBD consists of about 70 residues and is defined as the minimal region required for binding to ...

  14. XM_040677043.2 → XP_040532977.1  methyl-CpG-binding domain protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y461, A0A8V0YB25
    Conserved Domains (2) summary
    cd05835
    Location:1624 → 1714
    Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
    cl00110
    Location:16 → 79
    MBD; MeCP2, MBD1, MBD2, MBD3, MBD4, CLLD8-like, and BAZ2A-like proteins constitute a family of proteins that share the methyl-CpG-binding domain (MBD). The MBD consists of about 70 residues and is defined as the minimal region required for binding to ...
Nucleotide Protein
Heading Accession and Version

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