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PRSS12 serine protease 12 [ Gallus gallus (chicken) ]

Gene ID: 422685, updated on 5-Mar-2024

Summary

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Symbol
PRSS12provided by CGNC
Full Name
serine protease 12provided by CGNC
Primary source
CGNC:9096
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 4
Exon count:
13
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 4 NC_052535.1 (54529925..54571895)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 4 NC_052576.1 (54529917..54571836)

Chromosome 4 - NC_052535.1Genomic Context describing neighboring genes Neighboring gene SEC24 homolog D, COPII coat complex component Neighboring gene small nucleolar RNA SNORA24 Neighboring gene methyltransferase like 14 Neighboring gene N-deacetylase and N-sulfotransferase 3 Neighboring gene uncharacterized LOC107051710 Neighboring gene N-deacetylase and N-sulfotransferase 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
neurotrypsin
Names
protease, serine 12
protease, serine, 12 (neurotrypsin, motopsin)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052535.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    54529925..54571895
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015276362.4 → XP_015131848.3  neurotrypsin

    UniProtKB/TrEMBL
    A0A8V0XPP3
    Conserved Domains (2) summary
    smart00202
    Location:227 → 327
    SR; Scavenger receptor Cys-rich
    cd00190
    Location:578 → 819
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052576.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    54529917..54571836
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040669936.2 → XP_040525870.1  neurotrypsin

    UniProtKB/TrEMBL
    A0A8V0XPP3
    Conserved Domains (2) summary
    smart00202
    Location:227 → 327
    SR; Scavenger receptor Cys-rich
    cd00190
    Location:578 → 819
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
Nucleotide Protein
Heading Accession and Version

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