NOD1 nucleotide binding oligomerization domain containing 1 [Gallus gallus (chicken)] - Gene

Summary

Symbol: NOD1provided by CGNC
Full Name: nucleotide binding oligomerization domain containing 1provided by CGNC
Primary source: CGNC:8767
See related: Ensembl:ENSGALG00010016856
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	2	NC_052533.1 (41143745..41169402)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	2	NC_052574.1 (41197538..41223208)

Chromosome 2 - NC_052533.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Findings indicate the important role of chicken nucleotide-binding oligomerization domain-containing protein-1 (NOD1) in response to pathogenic invasion.
Title: Molecular characterization, expression, and functional analysis of NOD1 in Qingyuan partridge chicken.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of apoptotic process	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: nucleotide-binding oligomerization domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001318438.1 → NP_001305367.1 nucleotide-binding oligomerization domain-containing protein 1

Status: PROVISIONAL

Source sequence(s)

JX465487

UniProtKB/TrEMBL

A0A8V0Z507, J9Z1F6

Conserved Domains (7) summary

cd08324
Location:26 → 110

CARD_NOD1_CARD4; Caspase activation and recruitment domain similar to that found in NOD1

sd00033
Location:706 → 727

LRR_RI; leucine-rich repeat [structural motif]

sd00034
Location:678 → 702

LRR_AMN1; leucine-rich repeat [structural motif]

pfam05729
Location:202 → 372

NACHT; NACHT domain

pfam17776
Location:521 → 663

NLRC4_HD2; NLRC4 helical domain HD2

pfam17779
Location:462 → 519

NOD2_WH; NOD2 winged helix domain

cl42388
Location:654 → 939

PPP1R42; protein phosphatase 1 regulatory subunit 42

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

41143745..41169402

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_046923314.1 → XP_046779270.1 nucleotide-binding oligomerization domain-containing protein 1 isoform X1

UniProtKB/TrEMBL

A0A1D5PTE0, A0A8V0Z507
XM_025147215.3 → XP_025002983.1 nucleotide-binding oligomerization domain-containing protein 1 isoform X1

UniProtKB/TrEMBL

A0A1D5PTE0, A0A8V0Z507

Conserved Domains (7) summary

cd08324
Location:26 → 110

CARD_NOD1_CARD4; Caspase activation and recruitment domain similar to that found in NOD1

sd00033
Location:706 → 727

LRR_RI; leucine-rich repeat [structural motif]

sd00034
Location:678 → 702

LRR_AMN1; leucine-rich repeat [structural motif]

pfam05729
Location:202 → 372

NACHT; NACHT domain

pfam17776
Location:521 → 663

NLRC4_HD2; NLRC4 helical domain HD2

pfam17779
Location:462 → 519

NOD2_WH; NOD2 winged helix domain

cl39015
Location:654 → 939

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
XM_040682487.2 → XP_040538421.1 nucleotide-binding oligomerization domain-containing protein 1 isoform X1

UniProtKB/TrEMBL

A0A1D5PTE0, A0A8V0Z507

Related

ENSGALP00010023626.1, ENSGALT00010040661.1

Conserved Domains (7) summary

cd08324
Location:26 → 110

CARD_NOD1_CARD4; Caspase activation and recruitment domain similar to that found in NOD1

sd00033
Location:706 → 727

LRR_RI; leucine-rich repeat [structural motif]

sd00034
Location:678 → 702

LRR_AMN1; leucine-rich repeat [structural motif]

pfam05729
Location:202 → 372

NACHT; NACHT domain

pfam17776
Location:521 → 663

NLRC4_HD2; NLRC4 helical domain HD2

pfam17779
Location:462 → 519

NOD2_WH; NOD2 winged helix domain

cl39015
Location:654 → 939

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
XM_015281772.4 → XP_015137258.1 nucleotide-binding oligomerization domain-containing protein 1 isoform X1

UniProtKB/TrEMBL

A0A1D5PTE0, A0A8V0Z507

Conserved Domains (7) summary

cd08324
Location:26 → 110

CARD_NOD1_CARD4; Caspase activation and recruitment domain similar to that found in NOD1

sd00033
Location:706 → 727

LRR_RI; leucine-rich repeat [structural motif]

sd00034
Location:678 → 702

LRR_AMN1; leucine-rich repeat [structural motif]

pfam05729
Location:202 → 372

NACHT; NACHT domain

pfam17776
Location:521 → 663

NLRC4_HD2; NLRC4 helical domain HD2

pfam17779
Location:462 → 519

NOD2_WH; NOD2 winged helix domain

cl39015
Location:654 → 939

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

41197538..41223208

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_046911232.1 → XP_046767188.1 nucleotide-binding oligomerization domain-containing protein 1 isoform X1

UniProtKB/TrEMBL

A0A1D5PTE0, A0A8V0Z507
XM_046911230.1 → XP_046767186.1 nucleotide-binding oligomerization domain-containing protein 1 isoform X1

UniProtKB/TrEMBL

A0A1D5PTE0, A0A8V0Z507
XM_046911229.1 → XP_046767185.1 nucleotide-binding oligomerization domain-containing protein 1 isoform X1

UniProtKB/TrEMBL

A0A1D5PTE0, A0A8V0Z507
XM_046911231.1 → XP_046767187.1 nucleotide-binding oligomerization domain-containing protein 1 isoform X1

UniProtKB/TrEMBL

A0A1D5PTE0, A0A8V0Z507