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PLCZ1 phospholipase C zeta 1 [ Gallus gallus (chicken) ]

Gene ID: 418182, updated on 17-Aug-2024

Summary

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Symbol
PLCZ1provided by CGNC
Full Name
phospholipase C zeta 1provided by CGNC
Primary source
CGNC:50696
See related
Ensembl:ENSGALG00010013636
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See PLCZ1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
13
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (64241236..64284270, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (64564492..64607629, complement)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene LIM domain only 3 Neighboring gene phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma Neighboring gene RERG like Neighboring gene capping actin protein of muscle Z-line alpha subunit 3 Neighboring gene pleckstrin homology domain containing A5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Phospholipase Czeta, the trigger of egg activation in mammals, is present in a non-mammalian species. Coward K, et al. Reproduction, 2005 Aug. PMID 16049153
  2. Testis-specific novel transcripts in chicken: in situ localization and expression pattern profiling during sexual development. Rengaraj D, et al. Biol Reprod, 2008 Sep. PMID 18448841
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The expression of chicken PLCZ1 transcript was strongly detected in the cytoplasm of secondary spermatocytes, round spermatids, and elongated spermatids at adult age.
    Title: Testis-specific novel transcripts in chicken: in situ localization and expression pattern profiling during sexual development.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cytosolic calcium ion concentration involved in egg activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1
Names
phosphoinositide phospholipase C-zeta-1
NP_001034362.1
XP_040553123.1
XP_046763574.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039273.2 → NP_001034362.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1

    See identical proteins and their annotated locations for NP_001034362.1

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000012
    UniProtKB/Swiss-Prot
    Q2VRL0
    Related
    ENSGALP00010019429.1, ENSGALT00010032802.1
    Conserved Domains (4) summary
    cd00275
    Location:510 → 637
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08595
    Location:156 → 480
    PI-PLCc_zeta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-zeta
    PLN02952
    Location:73 → 632
    PLN02952; phosphoinositide phospholipase C
    pfam09279
    Location:74 → 156
    EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    64241236..64284270 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040697189.2 → XP_040553123.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 isoform X1

    Conserved Domains (2) summary
    cd08595
    Location:141 → 465
    PI-PLCc_zeta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-zeta
    PLN02952
    Location:58 → 617
    PLN02952; phosphoinositide phospholipase C

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    64564492..64607629 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046907618.1 → XP_046763574.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 isoform X1

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q2VRL0.1 GenPept UniProtKB/Swiss-Prot:Q2VRL0

Gene LinkOut

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