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ALCAM activated leukocyte cell adhesion molecule [ Sus scrofa (pig) ]

Gene ID: 397269, updated on 5-Mar-2024

Summary

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Official Symbol
ALCAMprovided by VGNC
Official Full Name
activated leukocyte cell adhesion moleculeprovided by VGNC
Primary source
VGNC:VGNC:85236
See related
Ensembl:ENSSSCG00000011946
Gene type
protein coding
RefSeq status
MODEL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Ubiquitous expression in lung (RPKM 34.7), kidney (RPKM 21.6) and 7 other tissues See more
Orthologs
human mouse all
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Genomic context

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See ALCAM in Genome Data Viewer
Location:
chromosome: 13
Exon count:
16
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 13 NC_010455.5 (153794991..153998241, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 13 NC_010455.4 (162988454..163045771, complement)

Chromosome 13 - NC_010455.5Genomic Context describing neighboring genes Neighboring gene Cbl proto-oncogene B Neighboring gene uncharacterized LOC110256435 Neighboring gene IST1 homolog pseudogene Neighboring gene uncharacterized LOC110256436 Neighboring gene uncharacterized LOC102159520

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. Side-specific expression of activated leukocyte adhesion molecule (ALCAM; CD166) in pathosusceptible regions of swine aortic valve endothelium. Guerraty MA, et al. J Heart Valve Dis, 2011 Mar. PMID 21560815, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. ALCAM up-regulation by hypercholesterolemia suggests a side-specific spatial role in the recruitment of leukocytes to aortic valve sclerosis sites.
    Title: Side-specific expression of activated leukocyte adhesion molecule (ALCAM; CD166) in pathosusceptible regions of swine aortic valve endothelium.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
CD166 antigen

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010455.5 Reference Sscrofa11.1 Primary Assembly

    Range
    153794991..153998241 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013982482.2 → XP_013837936.1  CD166 antigen isoform X2

    UniProtKB/TrEMBL
    A0A8D1U7Q4, A0A8D1UMV5, K7GLE8, K7GQN5, K9IWH1
    Related
    ENSSSCP00000028677.3, ENSSSCT00000034028.4
    Conserved Domains (6) summary
    smart00406
    Location:41 → 113
    IGv; Immunoglobulin V-Type
    smart00410
    Location:255 → 329
    IG_like; Immunoglobulin like
    pfam08205
    Location:137 → 231
    C2-set_2; CD80-like C2-set immunoglobulin domain
    pfam13895
    Location:346 → 412
    Ig_2; Immunoglobulin domain
    pfam13927
    Location:256 → 313
    Ig_3; Immunoglobulin domain
    cl11960
    Location:415 → 488
    Ig; Immunoglobulin domain

  2. XM_003358827.5 → XP_003358875.3  CD166 antigen isoform X1

    UniProtKB/TrEMBL
    A0A4X1SHK9, A0A5K1UB62, A0A8D1U7Q4
    Related
    ENSSSCP00000012727.5, ENSSSCT00000013072.6
    Conserved Domains (5) summary
    smart00406
    Location:41 → 113
    IGv; Immunoglobulin V-Type
    smart00410
    Location:255 → 329
    IG_like; Immunoglobulin like
    pfam08205
    Location:137 → 231
    C2-set_2; CD80-like C2-set immunoglobulin domain
    pfam13895
    Location:346 → 412
    Ig_2; Immunoglobulin domain
    cl11960
    Location:415 → 488
    Ig; Immunoglobulin domain

  3. XM_021070497.1 → XP_020926156.1  CD166 antigen isoform X1

    UniProtKB/TrEMBL
    A0A4X1SHK9, A0A5K1UB62, A0A8D1U7Q4
    Related
    ENSSSCP00000030207.3, ENSSSCT00000032688.4
    Conserved Domains (5) summary
    smart00406
    Location:41 → 113
    IGv; Immunoglobulin V-Type
    smart00410
    Location:255 → 329
    IG_like; Immunoglobulin like
    pfam08205
    Location:137 → 231
    C2-set_2; CD80-like C2-set immunoglobulin domain
    pfam13895
    Location:346 → 412
    Ig_2; Immunoglobulin domain
    cl11960
    Location:415 → 488
    Ig; Immunoglobulin domain

  4. XM_021070498.1 → XP_020926157.1  CD166 antigen isoform X1

    UniProtKB/TrEMBL
    A0A4X1SHK9, A0A5K1UB62, A0A8D1U7Q4
    Conserved Domains (5) summary
    smart00406
    Location:41 → 113
    IGv; Immunoglobulin V-Type
    smart00410
    Location:255 → 329
    IG_like; Immunoglobulin like
    pfam08205
    Location:137 → 231
    C2-set_2; CD80-like C2-set immunoglobulin domain
    pfam13895
    Location:346 → 412
    Ig_2; Immunoglobulin domain
    cl11960
    Location:415 → 488
    Ig; Immunoglobulin domain
Nucleotide Protein Strain
Heading Accession and Version

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