CXCL14 C-X-C motif chemokine ligand 14 [Gallus gallus (chicken)] - Gene

Summary

Symbol: CXCL14provided by CGNC
Full Name: C-X-C motif chemokine ligand 14provided by CGNC
Primary source: CGNC:4774
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: JSC
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 13

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	13	NC_052544.1 (14936550..14943837)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	13	NC_052585.1 (14948718..14955999)

Chromosome 13 - NC_052544.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

scRNA of the developing chick cochlea identified four distinct subgroups for hair cells and CXCL14 expression is specifically associated with tall hair cells.
Title: Cell-type identity of the avian cochlea.
CXCL14 plays a critical role in modulating neurogenesis and inhibiting ectopic vascularization of the cornea during ocular development.
Title: Knockdown of CXCL14 disrupts neurovascular patterning during ocular development.
The unique and non-overlapping patterns of CXCL12 and CXCL14 expression in ocular tissues suggest that these two chemokines may interact and have important functions in cell proliferation, differentiation and migration during eye development.
Title: Expression of CXCL12 and CXCL14 during eye development in chick and mouse.
It is possible that CXCL14 may regulate tissue growth during embryonic development.
Title: CXCL14 expression during chick embryonic development.
Study identifies CXCL14 as a novel marker of tendon connective tissue.
Title: Comparative expression pattern analysis of the highly conserved chemokines SDF1 and CXCL14 during amniote embryonic development.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables chemokine activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in antimicrobial humoral immune response mediated by antimicrobial peptide	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cell chemotaxis	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: C-X-C motif chemokine 14

Names: chemokine (C-X-C motif) ligand 14; jun-suppressed chemokine

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.