atad1a ATPase family AAA domain containing 1a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: atad1aprovided by ZNC
Official Full Name: ATPase family AAA domain containing 1aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030616-593
See related: Ensembl:ENSDARG00000023267 AllianceGenome:ZFIN:ZDB-GENE-030616-593
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: ATPase; zgc:101570; si:zc156n3.1
Summary: Predicted to enable ATP binding activity. Predicted to be located in mitochondrial outer membrane; peroxisomal membrane; and postsynaptic membrane. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in hyperekplexia 4. Orthologous to human ATAD1 (ATPase family AAA domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 5

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	5	NC_007116.7 (16718919..16734062, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	5	NC_007116.6 (16214923..16230066, complement)

Chromosome 5 - NC_007116.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info
enables membrane protein dislocase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in extraction of mislocalized protein from mitochondrial outer membrane	IBA Inferred from Biological aspect of Ancestor more info
involved_in extraction of mislocalized protein from mitochondrial outer membrane	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrial outer membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrial outer membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial outer membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info
located_in peroxisomal membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in peroxisome	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in postsynaptic membrane	IEA Inferred from Electronic Annotation more info
located_in synapse	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: outer mitochondrial transmembrane helix translocase

Names: ATPase family AAA domain-containing protein 1-A

NP_001004640.1

EC 3.6.1.3

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001004640.3 → NP_001004640.1 outer mitochondrial transmembrane helix translocase

See identical proteins and their annotated locations for NP_001004640.1

Status: VALIDATED

Source sequence(s)

CU929238, EH554125, EH565751

UniProtKB/Swiss-Prot

Q66IE9, Q7ZZ25

UniProtKB/TrEMBL

B2GQN7

Related

ENSDARP00000035974.7, ENSDART00000035859.8

Conserved Domains (2) summary

smart00382
Location:128 → 254

AAA; ATPases associated with a variety of cellular activities

pfam00004
Location:132 → 262

AAA; ATPase family associated with various cellular activities (AAA)

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007116.7 Reference GRCz11 Primary Assembly

Range

16718919..16734062 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001007112.2: Suppressed sequence

Description

NM_001007112.2: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.