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ell2 elongation factor for RNA polymerase II 2 [ Danio rerio (zebrafish) ]

Gene ID: 322997, updated on 17-Sep-2024

Summary

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Official Symbol
ell2provided by ZNC
Official Full Name
elongation factor for RNA polymerase II 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-1717
See related
Ensembl:ENSDARG00000006251 AllianceGenome:ZFIN:ZDB-GENE-030131-1717
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
cb244; fb78f03; sb:cb244; im:3814960; wu:fb78f03
Summary
Predicted to act upstream of or within transcription elongation from RNA polymerase II promoter. Predicted to be located in nucleus. Predicted to be part of transcription elongation factor complex. Is expressed in several structures, including anterior axial hypoblast; hatching gland; mesoderm; musculature system; and sensory system. Orthologous to human ELL2 (elongation factor for RNA polymerase II 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 21
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (11749104..11774965)
105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (11656476..11682337)

Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137488783 Neighboring gene uncharacterized LOC108180799 Neighboring gene proprotein convertase subtilisin/kexin type 1 Neighboring gene Rho related BTB domain containing 3 Neighboring gene glutaredoxin (thioltransferase) Neighboring gene uncharacterized LOC137488784

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. The medaka novel immune-type receptor (NITR) gene clusters reveal an extraordinary degree of divergence in variable domains. Desai S, et al. BMC Evol Biol, 2008 Jun 19. PMID 18565225, Free PMC Article
  2. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  3. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables translation elongation factor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in positive regulation of transcription elongation by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in snRNA transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within transcription elongation by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within translation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within translational elongation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of transcription elongation factor complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of transcription elongation factor complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
RNA polymerase II elongation factor ELL2
Names
elongation factor, RNA polymerase II 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001083812.2 → NP_001077281.2  RNA polymerase II elongation factor ELL2

    Status: VALIDATED

    Source sequence(s)
    BC085600, BI673398, BM096368, BX511081, CT677237
    UniProtKB/TrEMBL
    A0A8M1NDW7, F1R2K7, Q5U3C7
    Related
    ENSDARP00000093185.3, ENSDART00000102408.5
    Conserved Domains (2) summary
    pfam07303
    Location:552 → 647
    Occludin_ELL; Occludin homology domain
    pfam10390
    Location:7 → 283
    ELL; RNA polymerase II elongation factor ELL

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007132.7 Reference GRCz11 Primary Assembly

    Range
    11749104..11774965
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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