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Fbxo33 F-box protein 33 [ Rattus norvegicus (Norway rat) ]

Gene ID: 314157, updated on 17-Aug-2024

Summary

Official Symbol
Fbxo33provided by RGD
Official Full Name
F-box protein 33provided by RGD
Primary source
RGD:1307543
See related
EnsemblRapid:ENSRNOG00000005285 AllianceGenome:RGD:1307543
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in positive regulation of protein ubiquitination. Predicted to be part of SCF ubiquitin ligase complex. Orthologous to human FBXO33 (F-box protein 33). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Spleen (RPKM 96.6), Thymus (RPKM 94.2) and 9 other tissues See more
Orthologs
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Genomic context

Location:
6q23
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (82635509..82669441, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (76900619..76934232, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (80302291..80334536, complement)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene pinin, desmosome associated protein Neighboring gene MIA SH3 domain ER export factor 2 Neighboring gene small nucleolar RNA, H/ACA box 26 like 1 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001399654.1NP_001386583.1  F-box only protein 33

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/TrEMBL
    A6HBR6, D3ZVL5
    Related
    ENSRNOP00000091589.1, ENSRNOT00000094790.2

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    82635509..82669441 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039112237.2XP_038968165.1  F-box only protein 33 isoform X1

  2. XM_039112238.2XP_038968166.1  F-box only protein 33 isoform X2

    Conserved Domains (1) summary
    pfam12937
    Location:72111
    F-box-like

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001108023.1: Suppressed sequence

    Description
    NM_001108023.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.