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Naa38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit [ Rattus norvegicus (Norway rat) ]

Gene ID: 287429, updated on 17-Aug-2024

Summary

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Official Symbol
Naa38provided by RGD
Official Full Name
N(alpha)-acetyltransferase 38, NatC auxiliary subunitprovided by RGD
Primary source
RGD:1559617
See related
EnsemblRapid:ENSRNOG00000090113 AllianceGenome:RGD:1559617
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Lsmd1; RGD1559617
Summary
Predicted to be involved in negative regulation of apoptotic process. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of NatC complex. Orthologous to human NAA38 (N-alpha-acetyltransferase 38, NatC auxiliary subunit). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Adrenal (RPKM 177.1), Heart (RPKM 175.4) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
10q24
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (54588304..54617715)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (54117754..54118913)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (55997614..55998691)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene ring finger protein 227 Neighboring gene small Cajal body-specific RNA 21 Neighboring gene chromodomain helicase DNA binding protein 3 Neighboring gene cytochrome b5 domain containing 1 Neighboring gene transmembrane protein 88 Neighboring gene lysine demethylase 6B Neighboring gene dynein, axonemal, heavy chain 2 Neighboring gene uncharacterized LOC102557224

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Knockdown of human N alpha-terminal acetyltransferase complex C leads to p53-dependent apoptosis and aberrant human Arl8b localization. Starheim KK, et al. Mol Cell Biol, 2009 Jul. PMID 19398576, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in negative regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
part_of NatC complex ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
N(alpha)-acetyltransferase 38, NatC auxiliary subunit
Names
LSM domain-containing 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001105794.3 → NP_001099264.2  N(alpha)-acetyltransferase 38, NatC auxiliary subunit

    See identical proteins and their annotated locations for NP_001099264.2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/TrEMBL
    A6HFQ6
    Conserved Domains (1) summary
    cd06168
    Location:42 → 115
    LSMD1; LSM domain containing 1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    54588304..54617715
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039085444.2 → XP_038941372.1  N(alpha)-acetyltransferase 38, NatC auxiliary subunit isoform X1

    UniProtKB/TrEMBL
    G3V785
    Related
    ENSRNOP00000100970.1, ENSRNOT00000167755.1

  2. XM_063268637.1 → XP_063124707.1  N(alpha)-acetyltransferase 38, NatC auxiliary subunit isoform X2

    UniProtKB/TrEMBL
    A6HFQ6
Nucleotide Protein Strain
Heading Accession and Version

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