Format

Send to:

Choose Destination

Ep300 E1A binding protein p300 [ Rattus norvegicus (Norway rat) ]

Gene ID: 170915, updated on 8-May-2016
Official Symbol
Ep300provided by RGD
Official Full Name
E1A binding protein p300provided by RGD
Primary source
RGD:620036
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Summary
endogenous transcriptional coactivator related to fatty acid and vitamin A metabolism [RGD, Feb 2006]
Orthologs
Location:
7q34
Exon count:
30
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (122818204..122889055)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 7 NC_005106.3 (122792742..122863551)

Chromosome 7 - NC_005106.4Genomic Context describing neighboring genes Neighboring gene ribosomal protein L37a, pseudogene 2 Neighboring gene ring-box 1 Neighboring gene L3MBTL2 polycomb repressive complex 1 subunit Neighboring gene chondroadherin-like Neighboring gene RAN GTPase activating protein 1

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Adherens junction, organism-specific biosystem (from KEGG)
    Adherens junction, organism-specific biosystemCell-cell adherens junctions (AJs), the most common type of intercellular adhesions, are important for maintaining tissue architecture and cell polarity and can limit cell movement and proliferation....
  • Adherens junction, conserved biosystem (from KEGG)
    Adherens junction, conserved biosystemCell-cell adherens junctions (AJs), the most common type of intercellular adhesions, are important for maintaining tissue architecture and cell polarity and can limit cell movement and proliferation....
  • Androgen Receptor Signaling Pathway, organism-specific biosystem (from WikiPathways)
    Androgen Receptor Signaling Pathway, organism-specific biosystemThe androgen receptor is a member of the nuclear receptor family of ligand activated transcription factors. These receptors bind to steroid hormones, thyroid hormone, retinoids and vitamin D among ot...
  • Cell cycle, organism-specific biosystem (from WikiPathways)
    Cell cycle, organism-specific biosystem(From http://en.wikipedia.org/wiki/Cell_cycle) The cell cycle is the series of events that takes place in a cell leading to its division and duplication (replication). Regulation of the cell cycle in...
  • Cell cycle, organism-specific biosystem (from KEGG)
    Cell cycle, organism-specific biosystemMitotic cell cycle progression is accomplished through a reproducible sequence of events, DNA replication (S phase) and mitosis (M phase) separated temporally by gaps known as G1 and G2 phases. Cycli...
  • Cell cycle, conserved biosystem (from KEGG)
    Cell cycle, conserved biosystemMitotic cell cycle progression is accomplished through a reproducible sequence of events, DNA replication (S phase) and mitosis (M phase) separated temporally by gaps known as G1 and G2 phases. Cycli...
  • Delta-Notch Signaling Pathway, organism-specific biosystem (from WikiPathways)
    Delta-Notch Signaling Pathway, organism-specific biosystemThere are 4 Notch receptors in humans (Notch 1-4) that bind to a family of 5 ligands (Jagged 1 and 2 and Delta-like 1-3). The Notch receptors are expressed on the cell surface as heterodimeric protei...
  • Epstein-Barr virus infection, organism-specific biosystem (from KEGG)
    Epstein-Barr virus infection, organism-specific biosystemEpstein-Barr virus (EBV) is a ubiquitous human herpesvirus that is associated with oncogenesis. EBV infection to primary human B lymphocytes leads to induction of EBV-specific HLA-restricted cytotoxi...
  • Epstein-Barr virus infection, conserved biosystem (from KEGG)
    Epstein-Barr virus infection, conserved biosystemEpstein-Barr virus (EBV) is a ubiquitous human herpesvirus that is associated with oncogenesis. EBV infection to primary human B lymphocytes leads to induction of EBV-specific HLA-restricted cytotoxi...
  • Estrogen signalling, organism-specific biosystem (from WikiPathways)
    Estrogen signalling, organism-specific biosystemEstrogen receptor refers to a group of receptors which are activated by the hormone 17β-estradiol (estrogen). Two types of estrogen receptor exist: ER which is a member of the nuclear h...
  • FoxO signaling pathway, organism-specific biosystem (from KEGG)
    FoxO signaling pathway, organism-specific biosystemThe forkhead box O (FOXO) family of transcription factors regulates the expression of genes in cellular physiological events including apoptosis, cell-cycle control, glucose metabolism, oxidative str...
  • Glucagon signaling pathway, organism-specific biosystem (from KEGG)
    Glucagon signaling pathway, organism-specific biosystemGlucagon is conventionally regarded as a counterregulatory hormone for insulin and plays a critical anti-hypoglycemic role by maintaining glucose homeostasis in both animals and humans. To increase ...
  • Glucagon signaling pathway, conserved biosystem (from KEGG)
    Glucagon signaling pathway, conserved biosystemGlucagon is conventionally regarded as a counterregulatory hormone for insulin and plays a critical anti-hypoglycemic role by maintaining glucose homeostasis in both animals and humans. To increase ...
  • HIF-1 signaling pathway, organism-specific biosystem (from KEGG)
    HIF-1 signaling pathway, organism-specific biosystemHypoxia-inducible factor 1 (HIF-1) is a transcription factor that functions as a master regulator of oxygen homeostasis. It consists of two subunits: an inducibly-expressed HIF-1alpha subunit and a c...
  • HTLV-I infection, organism-specific biosystem (from KEGG)
    HTLV-I infection, organism-specific biosystemHuman T-lymphotropic virus type 1 (HTLV-1) is a pathogenic retrovirus that is associated with adult T-cell leukemia/lymphoma (ATL). It is also strongly implicated in non-neoplastic chronic inflammato...
  • HTLV-I infection, conserved biosystem (from KEGG)
    HTLV-I infection, conserved biosystemHuman T-lymphotropic virus type 1 (HTLV-1) is a pathogenic retrovirus that is associated with adult T-cell leukemia/lymphoma (ATL). It is also strongly implicated in non-neoplastic chronic inflammato...
  • Hepatitis B, organism-specific biosystem (from KEGG)
    Hepatitis B, organism-specific biosystemHepatitis B virus (HBV) is an enveloped virus and contains a partially double-stranded relaxed circular DNA (RC-DNA) genome. After entry into hepatocytes, HBV RC-DNA is transported to the nucleus and...
  • Herpes simplex infection, organism-specific biosystem (from KEGG)
    Herpes simplex infection, organism-specific biosystemHerpes simplex virus (HSV) infections are very common worldwide, with the prevalence of HSV-1 reaching up to 80%-90%. Primary infection with HSV takes place in the mucosa, followed by the establishme...
  • Herpes simplex infection, conserved biosystem (from KEGG)
    Herpes simplex infection, conserved biosystemHerpes simplex virus (HSV) infections are very common worldwide, with the prevalence of HSV-1 reaching up to 80%-90%. Primary infection with HSV takes place in the mucosa, followed by the establishme...
  • Huntington's disease, organism-specific biosystem (from KEGG)
    Huntington's disease, organism-specific biosystemHuntington disease (HD) is an autosomal-dominant neurodegenerative disorder that primarily affects medium spiny striatal neurons (MSN). The symptoms are choreiform, involuntary movements, personality...
  • Huntington's disease, conserved biosystem (from KEGG)
    Huntington's disease, conserved biosystemHuntington disease (HD) is an autosomal-dominant neurodegenerative disorder that primarily affects medium spiny striatal neurons (MSN). The symptoms are choreiform, involuntary movements, personality...
  • IL-4 Signaling Pathway, organism-specific biosystem (from WikiPathways)
    IL-4 Signaling Pathway, organism-specific biosystem
    IL-4 Signaling Pathway
  • IL-6 Signaling Pathway, organism-specific biosystem (from WikiPathways)
    IL-6 Signaling Pathway, organism-specific biosystem
    IL-6 Signaling Pathway
  • Influenza A, organism-specific biosystem (from KEGG)
    Influenza A, organism-specific biosystemInfluenza is a contagious respiratory disease caused by influenza virus infection. Influenza A virus is responsible for both annual seasonal epidemics and periodic worldwide pandemics. Novel strains ...
  • Influenza A, conserved biosystem (from KEGG)
    Influenza A, conserved biosystemInfluenza is a contagious respiratory disease caused by influenza virus infection. Influenza A virus is responsible for both annual seasonal epidemics and periodic worldwide pandemics. Novel strains ...
  • Jak-STAT signaling pathway, organism-specific biosystem (from KEGG)
    Jak-STAT signaling pathway, organism-specific biosystemThe Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway is one of a handful of pleiotropic cascades used to transduce a multitude of signals for development and homeost...
  • Jak-STAT signaling pathway, conserved biosystem (from KEGG)
    Jak-STAT signaling pathway, conserved biosystemThe Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway is one of a handful of pleiotropic cascades used to transduce a multitude of signals for development and homeost...
  • Kit Receptor Signaling Pathway, organism-specific biosystem (from WikiPathways)
    Kit Receptor Signaling Pathway, organism-specific biosystemKit is a receptor protein tyrosine kinase, which is a receptor for stem cell factor or kit ligand. Signaling through Kit is important for formation of red cells, lymphocytes, mast cells and platelets...
  • Long-term potentiation, organism-specific biosystem (from KEGG)
    Long-term potentiation, organism-specific biosystemHippocampal long-term potentiation (LTP), a long-lasting increase in synaptic efficacy, is the molecular basis for learning and memory. Tetanic stimulation of afferents in the CA1 region of the hippo...
  • Long-term potentiation, conserved biosystem (from KEGG)
    Long-term potentiation, conserved biosystemHippocampal long-term potentiation (LTP), a long-lasting increase in synaptic efficacy, is the molecular basis for learning and memory. Tetanic stimulation of afferents in the CA1 region of the hippo...
  • Melanogenesis, organism-specific biosystem (from KEGG)
    Melanogenesis, organism-specific biosystemCutaneous melanin pigment plays a critical role in camouflage, mimicry, social communication, and protection against harmful effects of solar radiation. Melanogenesis is under complex regulatory cont...
  • Melanogenesis, conserved biosystem (from KEGG)
    Melanogenesis, conserved biosystemCutaneous melanin pigment plays a critical role in camouflage, mimicry, social communication, and protection against harmful effects of solar radiation. Melanogenesis is under complex regulatory cont...
  • MicroRNAs in cancer, organism-specific biosystem (from KEGG)
    MicroRNAs in cancer, organism-specific biosystemMicroRNA (miRNA) is a cluster of small non-encoding RNA molecules of 21 - 23 nucleotides in length, which controls gene expression post-transcriptionally either via the degradation of target mRNAs or...
  • MicroRNAs in cancer, conserved biosystem (from KEGG)
    MicroRNAs in cancer, conserved biosystemMicroRNA (miRNA) is a cluster of small non-encoding RNA molecules of 21 - 23 nucleotides in length, which controls gene expression post-transcriptionally either via the degradation of target mRNAs or...
  • NFE2L2, organism-specific biosystem (from WikiPathways)
    NFE2L2, organism-specific biosystem
    NFE2L2
  • Notch signaling pathway, organism-specific biosystem (from KEGG)
    Notch signaling pathway, organism-specific biosystemThe Notch signaling pathway is an evolutionarily conserved, intercellular signaling mechanism essential for proper embryonic development in all metazoan organisms in the Animal kingdom. The Notch pro...
  • Notch signaling pathway, conserved biosystem (from KEGG)
    Notch signaling pathway, conserved biosystemThe Notch signaling pathway is an evolutionarily conserved, intercellular signaling mechanism essential for proper embryonic development in all metazoan organisms in the Animal kingdom. The Notch pro...
  • Pathways in cancer, organism-specific biosystem (from KEGG)
    Pathways in cancer, organism-specific biosystem
    Pathways in cancer
  • Prostate cancer, organism-specific biosystem (from KEGG)
    Prostate cancer, organism-specific biosystemProstate cancer constitutes a major health problem in Western countries. It is the most frequently diagnosed cancer among men and the second leading cause of male cancer deaths. The identification of...
  • Prostate cancer, conserved biosystem (from KEGG)
    Prostate cancer, conserved biosystemProstate cancer constitutes a major health problem in Western countries. It is the most frequently diagnosed cancer among men and the second leading cause of male cancer deaths. The identification of...
  • Renal cell carcinoma, organism-specific biosystem (from KEGG)
    Renal cell carcinoma, organism-specific biosystemRenal cell cancer (RCC) accounts for ~3% of human malignancies and its incidence appears to be rising. Although most cases of RCC seem to occur sporadically, an inherited predisposition to renal canc...
  • Renal cell carcinoma, conserved biosystem (from KEGG)
    Renal cell carcinoma, conserved biosystemRenal cell cancer (RCC) accounts for ~3% of human malignancies and its incidence appears to be rising. Although most cases of RCC seem to occur sporadically, an inherited predisposition to renal canc...
  • TGF Beta Signaling Pathway, organism-specific biosystem (from WikiPathways)
    TGF Beta Signaling Pathway, organism-specific biosystemThe Transforming growth factor beta (TGFβ) signaling pathway is involved in many cellular processes in both the adult organism and the developing embryo including cell growth, cell differentiat...
  • TGF-beta Receptor Signaling Pathway, organism-specific biosystem (from WikiPathways)
    TGF-beta Receptor Signaling Pathway, organism-specific biosystem
    TGF-beta Receptor Signaling Pathway
  • TGF-beta signaling pathway, organism-specific biosystem (from KEGG)
    TGF-beta signaling pathway, organism-specific biosystemThe transforming growth factor-beta (TGF-beta) family members, which include TGF-betas, activins and bone morphogenetic proteins (BMPs), are structurally related secreted cytokines found in species r...
  • TGF-beta signaling pathway, conserved biosystem (from KEGG)
    TGF-beta signaling pathway, conserved biosystemThe transforming growth factor-beta (TGF-beta) family members, which include TGF-betas, activins and bone morphogenetic proteins (BMPs), are structurally related secreted cytokines found in species r...
  • Thyroid hormone signaling pathway, organism-specific biosystem (from KEGG)
    Thyroid hormone signaling pathway, organism-specific biosystemThe thyroid hormones (THs) are important regulators of growth, development and metabolism. The action of TH is mainly mediated by T3 (3,5,3'-triiodo-L-thyronine). Thyroid hormones, L-thyroxine (T4) a...
  • Tuberculosis, organism-specific biosystem (from KEGG)
    Tuberculosis, organism-specific biosystemTuberculosis, or TB, is an infectious disease caused by Mycobacterium tuberculosis. One third of the world's population is thought to be infected with TB. About 90% of those infected result in latent...
  • Tuberculosis, conserved biosystem (from KEGG)
    Tuberculosis, conserved biosystemTuberculosis, or TB, is an infectious disease caused by Mycobacterium tuberculosis. One third of the world's population is thought to be infected with TB. About 90% of those infected result in latent...
  • Viral carcinogenesis, organism-specific biosystem (from KEGG)
    Viral carcinogenesis, organism-specific biosystemThere is a strong association between viruses and the development of human malignancies. We now know that at least six human viruses, Epstein-Barr virus (EBV), hepatitis B virus (HBV), hepatitis C vi...
  • Viral carcinogenesis, conserved biosystem (from KEGG)
    Viral carcinogenesis, conserved biosystemThere is a strong association between viruses and the development of human malignancies. We now know that at least six human viruses, Epstein-Barr virus (EBV), hepatitis B virus (HBV), hepatitis C vi...
  • Wnt Signaling Pathway NetPath, organism-specific biosystem (from WikiPathways)
    Wnt Signaling Pathway NetPath, organism-specific biosystemWnt family of proteins are a large family of cysteine-rich secreted glycoproteins that regulate cell-cell interactions. They bind to members of the Frizzled family of 7 transmembrane receptors. Bindi...
  • Wnt Signaling Pathway and Pluripotency, organism-specific biosystem (from WikiPathways)
    Wnt Signaling Pathway and Pluripotency, organism-specific biosystemThis pathway was adapted from several resources and is designed to provide a theoretical frame-work for examining Wnt signaling and interacting components in the context of embryonic stem-cell pluri...
  • Wnt signaling pathway, organism-specific biosystem (from KEGG)
    Wnt signaling pathway, organism-specific biosystemWnt proteins are secreted morphogens that are required for basic developmental processes, such as cell-fate specification, progenitor-cell proliferation and the control of asymmetric cell division, i...
  • Wnt signaling pathway, conserved biosystem (from KEGG)
    Wnt signaling pathway, conserved biosystemWnt proteins are secreted morphogens that are required for basic developmental processes, such as cell-fate specification, progenitor-cell proliferation and the control of asymmetric cell division, i...
  • cAMP signaling pathway, organism-specific biosystem (from KEGG)
    cAMP signaling pathway, organism-specific biosystemcAMP is one of the most common and universal second messengers, and its formation is promoted by adenylyl cyclase (AC) activation after ligation of G protein-coupled receptors (GPCRs) by ligands incl...
  • cAMP signaling pathway, conserved biosystem (from KEGG)
    cAMP signaling pathway, conserved biosystemcAMP is one of the most common and universal second messengers, and its formation is promoted by adenylyl cyclase (AC) activation after ligation of G protein-coupled receptors (GPCRs) by ligands incl...
  • genetic alternations of lung cancer, organism-specific biosystem (from WikiPathways)
    genetic alternations of lung cancer, organism-specific biosystemExpression patterns of two major tumor suppressor pathways in lung cancer. These pathways are functionally linked to lung cancer and play role as a component of checkpoints and growth inhibitory path...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
DNA binding ISO
Inferred from Sequence Orthology
more info
 
NF-kappaB binding IPI
Inferred from Physical Interaction
more info
PubMed 
RNA polymerase II activating transcription factor binding IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II activating transcription factor binding ISO
Inferred from Sequence Orthology
more info
 
RNA polymerase II core promoter proximal region sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
RNA polymerase II core promoter sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II core promoter sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
RNA polymerase II transcription factor binding ISO
Inferred from Sequence Orthology
more info
 
SMAD binding IPI
Inferred from Physical Interaction
more info
PubMed 
acetyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
activating transcription factor binding IPI
Inferred from Physical Interaction
more info
PubMed 
activating transcription factor binding ISO
Inferred from Sequence Orthology
more info
 
androgen receptor binding IEA
Inferred from Electronic Annotation
more info
 
androgen receptor binding ISO
Inferred from Sequence Orthology
more info
 
antigen binding IDA
Inferred from Direct Assay
more info
PubMed 
bHLH transcription factor binding IPI
Inferred from Physical Interaction
more info
PubMed 
beta-catenin binding IEA
Inferred from Electronic Annotation
more info
 
beta-catenin binding ISO
Inferred from Sequence Orthology
more info
 
chromatin DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
chromatin DNA binding ISO
Inferred from Sequence Orthology
more info
 
chromatin binding IDA
Inferred from Direct Assay
more info
PubMed 
chromatin binding ISO
Inferred from Sequence Orthology
more info
 
core promoter binding IDA
Inferred from Direct Assay
more info
PubMed 
core promoter binding ISO
Inferred from Sequence Orthology
more info
 
core promoter proximal region DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
damaged DNA binding IEA
Inferred from Electronic Annotation
more info
 
damaged DNA binding ISO
Inferred from Sequence Orthology
more info
 
glucocorticoid receptor binding IDA
Inferred from Direct Assay
more info
PubMed 
histone acetyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
histone acetyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
lysine N-acetyltransferase activity, acting on acetyl phosphate as donor IMP
Inferred from Mutant Phenotype
more info
PubMed 
lysine N-acetyltransferase activity, acting on acetyl phosphate as donor ISO
Inferred from Sequence Orthology
more info
 
mitogen-activated protein kinase binding IPI
Inferred from Physical Interaction
more info
PubMed 
nuclear hormone receptor binding ISO
Inferred from Sequence Orthology
more info
 
p53 binding IPI
Inferred from Physical Interaction
more info
PubMed 
p53 binding ISO
Inferred from Sequence Orthology
more info
 
peroxisome proliferator activated receptor binding IDA
Inferred from Direct Assay
more info
PubMed 
pre-mRNA intronic binding IEA
Inferred from Electronic Annotation
more info
 
pre-mRNA intronic binding ISO
Inferred from Sequence Orthology
more info
 
protein C-terminus binding IEA
Inferred from Electronic Annotation
more info
 
protein C-terminus binding ISO
Inferred from Sequence Orthology
more info
 
protein antigen binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein complex binding IDA
Inferred from Direct Assay
more info
PubMed 
protein complex binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein kinase binding IPI
Inferred from Physical Interaction
more info
PubMed 
transcription coactivator activity IEA
Inferred from Electronic Annotation
more info
 
transcription coactivator activity ISO
Inferred from Sequence Orthology
more info
 
contributes_to transcription coactivator activity ISO
Inferred from Sequence Orthology
more info
 
contributes_to transcription factor activity, sequence-specific DNA binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
transcription factor binding IDA
Inferred from Direct Assay
more info
PubMed 
transcription factor binding IPI
Inferred from Physical Interaction
more info
PubMed 
transcription factor binding ISO
Inferred from Sequence Orthology
more info
 
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding IEA
Inferred from Electronic Annotation
more info
 
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding ISO
Inferred from Sequence Orthology
more info
 
transferase activity, transferring acyl groups ISO
Inferred from Sequence Orthology
more info
 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
B cell differentiation IEA
Inferred from Electronic Annotation
more info
 
B cell differentiation ISO
Inferred from Sequence Orthology
more info
 
N-terminal peptidyl-lysine acetylation IEA
Inferred from Electronic Annotation
more info
 
N-terminal peptidyl-lysine acetylation ISO
Inferred from Sequence Orthology
more info
 
apoptotic process ISO
Inferred from Sequence Orthology
more info
 
cellular response to UV IEA
Inferred from Electronic Annotation
more info
 
cellular response to UV ISO
Inferred from Sequence Orthology
more info
 
cellular response to antibiotic IEP
Inferred from Expression Pattern
more info
PubMed 
cellular response to cAMP IEP
Inferred from Expression Pattern
more info
PubMed 
cellular response to dexamethasone stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
cellular response to drug IEP
Inferred from Expression Pattern
more info
PubMed 
cellular response to glucose stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
cellular response to hydrogen peroxide IEP
Inferred from Expression Pattern
more info
PubMed 
cellular response to mineralocorticoid stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
cellular response to nerve growth factor stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
cellular response to organic cyclic compound IEP
Inferred from Expression Pattern
more info
PubMed 
cellular response to retinoic acid IEP
Inferred from Expression Pattern
more info
PubMed 
cellular response to trichostatin A IEP
Inferred from Expression Pattern
more info
PubMed 
circadian rhythm IEA
Inferred from Electronic Annotation
more info
 
circadian rhythm ISO
Inferred from Sequence Orthology
more info
 
digestive tract development IEP
Inferred from Expression Pattern
more info
PubMed 
fat cell differentiation IEA
Inferred from Electronic Annotation
more info
 
fat cell differentiation ISO
Inferred from Sequence Orthology
more info
 
heart development IEA
Inferred from Electronic Annotation
more info
 
heart development ISO
Inferred from Sequence Orthology
more info
 
histone H2B acetylation IEA
Inferred from Electronic Annotation
more info
 
histone H2B acetylation ISO
Inferred from Sequence Orthology
more info
 
histone H3 acetylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
histone H4 acetylation IEA
Inferred from Electronic Annotation
more info
 
histone H4 acetylation ISO
Inferred from Sequence Orthology
more info
 
histone acetylation IMP
Inferred from Mutant Phenotype
more info
 
internal peptidyl-lysine acetylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
internal peptidyl-lysine acetylation ISO
Inferred from Sequence Orthology
more info
 
internal protein amino acid acetylation ISO
Inferred from Sequence Orthology
more info
 
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IEA
Inferred from Electronic Annotation
more info
 
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator ISO
Inferred from Sequence Orthology
more info
 
liver development IEP
Inferred from Expression Pattern
more info
PubMed 
lung development IEA
Inferred from Electronic Annotation
more info
 
lung development ISO
Inferred from Sequence Orthology
more info
 
megakaryocyte development IEA
Inferred from Electronic Annotation
more info
 
megakaryocyte development ISO
Inferred from Sequence Orthology
more info
 
memory IEP
Inferred from Expression Pattern
more info
PubMed 
negative regulation of cell death IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of cellular metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of miRNA metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of transcription from RNA polymerase II promoter IEA
Inferred from Electronic Annotation
more info
 
negative regulation of transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
organ morphogenesis IEA
Inferred from Electronic Annotation
more info
 
organ morphogenesis ISO
Inferred from Sequence Orthology
more info
 
platelet formation IEA
Inferred from Electronic Annotation
more info
 
platelet formation ISO
Inferred from Sequence Orthology
more info
 
positive regulation by host of viral transcription IEA
Inferred from Electronic Annotation
more info
 
positive regulation by host of viral transcription ISO
Inferred from Sequence Orthology
more info
 
positive regulation of DNA binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of axon extension IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of cell death IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of cell growth IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of cell size IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of cellular metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of collagen biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 
positive regulation of gene expression IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
positive regulation of glycoprotein biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of histone acetylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of muscle atrophy IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of protein acetylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of protein binding IEA
Inferred from Electronic Annotation
more info
 
positive regulation of protein binding ISO
Inferred from Sequence Orthology
more info
 
positive regulation of protein import into nucleus, translocation IMP
Inferred from Mutant Phenotype
more info
 
positive regulation of protein phosphorylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of protein secretion IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of proteolysis IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of sarcomere organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of sequence-specific DNA binding transcription factor activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of sequence-specific DNA binding transcription factor activity ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription from RNA polymerase II promoter IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response IEA
Inferred from Electronic Annotation
more info
 
positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
positive regulation of translation IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein acetylation ISO
Inferred from Sequence Orthology
more info
 
protein kinase B signaling IDA
Inferred from Direct Assay
more info
PubMed 
protein stabilization IEA
Inferred from Electronic Annotation
more info
 
protein stabilization ISO
Inferred from Sequence Orthology
more info
 
protein-DNA complex assembly IDA
Inferred from Direct Assay
more info
PubMed 
regulation of androgen receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
regulation of androgen receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
regulation of angiotensin metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
regulation of tubulin deacetylation IEA
Inferred from Electronic Annotation
more info
 
regulation of tubulin deacetylation ISO
Inferred from Sequence Orthology
more info
 
response to calcium ion IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to cobalt ion IEP
Inferred from Expression Pattern
more info
PubMed 
response to dexamethasone IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to drug IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to estrogen IEP
Inferred from Expression Pattern
more info
PubMed 
response to estrogen ISO
Inferred from Sequence Orthology
more info
 
response to ethanol IEP
Inferred from Expression Pattern
more info
PubMed 
response to fatty acid IEP
Inferred from Expression Pattern
more info
PubMed 
response to glucose IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to hydrogen peroxide IEP
Inferred from Expression Pattern
more info
PubMed 
response to hypoxia IEP
Inferred from Expression Pattern
more info
PubMed 
response to hypoxia ISO
Inferred from Sequence Orthology
more info
 
response to organic cyclic compound IEP
Inferred from Expression Pattern
more info
PubMed 
response to retinoic acid IEP
Inferred from Expression Pattern
more info
PubMed 
response to tumor necrosis factor IEP
Inferred from Expression Pattern
more info
PubMed 
skeletal muscle tissue development IEA
Inferred from Electronic Annotation
more info
 
skeletal muscle tissue development ISO
Inferred from Sequence Orthology
more info
 
somitogenesis IEA
Inferred from Electronic Annotation
more info
 
somitogenesis ISO
Inferred from Sequence Orthology
more info
 
transcription from RNA polymerase II promoter IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
chromatin IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
histone acetyltransferase complex IEA
Inferred from Electronic Annotation
more info
 
histone acetyltransferase complex ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
protein-DNA complex IDA
Inferred from Direct Assay
more info
PubMed 
transcription factor complex IC
Inferred by Curator
more info
PubMed 
transcription factor complex ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
histone acetyltransferase p300

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005106.4 Reference Rnor_6.0 Primary Assembly

    Range
    122818204..122889055
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008765878.1XP_008764100.1  

    Conserved Domains (10) summary
    cd05495
    Location:10381145
    Bromo_cbp_like; Bromodomain, cbp_like subfamily. Cbp (CREB binding protein or CREBBP) is an acetyltransferase acting on histone, which gives a specific tag for transcriptional activation and also acetylates non-histone proteins. CREBBP binds specifically to ...
    cd02337
    Location:16551695
    ZZ_CBP; Zinc finger, ZZ type. Zinc finger present in CBP/p300 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. CREB-binding protein (CBP) is a large multidomain protein that ...
    pfam02135
    Location:17201793
    zf-TAZ; TAZ zinc finger
    pfam02172
    Location:567647
    KIX; KIX domain
    pfam08214
    Location:12931599
    KAT11; Histone acetylation protein
    pfam08430
    Location:119218
    Fork_head_N; Forkhead N-terminal region
    pfam09030
    Location:19762085
    Creb_binding; Creb binding
    pfam09606
    Location:19442363
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cd15802
    Location:11571229
    RING_CBP-p300; atypical RING domain found in CREB-binding protein and p300 histone acetyltransferases
    cd15646
    Location:12301264
    PHD_p300; PHD finger found in histone acetyltransferase p300

Alternate Rn_Celera

Genomic

  1. AC_000075.1 Alternate Rn_Celera

    Range
    109426739..109497522
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001076610.4XP_001076610.1  

    Conserved Domains (10) summary
    cd05495
    Location:10491156
    Bromo_cbp_like; Bromodomain, cbp_like subfamily. Cbp (CREB binding protein or CREBBP) is an acetyltransferase acting on histone, which gives a specific tag for transcriptional activation and also acetylates non-histone proteins. CREBBP binds specifically to ...
    cd02337
    Location:16661706
    ZZ_CBP; Zinc finger, ZZ type. Zinc finger present in CBP/p300 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. CREB-binding protein (CBP) is a large multidomain protein that ...
    pfam02135
    Location:17311804
    zf-TAZ; TAZ zinc finger
    pfam02172
    Location:567647
    KIX; KIX domain
    pfam08214
    Location:13041610
    KAT11; Histone acetylation protein
    pfam08430
    Location:119218
    Fork_head_N; Forkhead N-terminal region
    pfam09030
    Location:19872096
    Creb_binding; Creb binding
    pfam09606
    Location:19552374
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cd15802
    Location:11681240
    RING_CBP-p300; atypical RING domain found in CREB-binding protein and p300 histone acetyltransferases
    cd15646
    Location:12411275
    PHD_p300; PHD finger found in histone acetyltransferase p300
  2. XM_006226166.2XP_006226228.1  

    Conserved Domains (10) summary
    cd05495
    Location:10491149
    Bromo_cbp_like; Bromodomain, cbp_like subfamily. Cbp (CREB binding protein or CREBBP) is an acetyltransferase acting on histone, which gives a specific tag for transcriptional activation and also acetylates non-histone proteins. CREBBP binds specifically to ...
    cd02337
    Location:16591699
    ZZ_CBP; Zinc finger, ZZ type. Zinc finger present in CBP/p300 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. CREB-binding protein (CBP) is a large multidomain protein that ...
    pfam02135
    Location:17241797
    zf-TAZ; TAZ zinc finger
    pfam02172
    Location:567647
    KIX; KIX domain
    pfam08214
    Location:12971603
    KAT11; Histone acetylation protein
    pfam08430
    Location:119218
    Fork_head_N; Forkhead N-terminal region
    pfam09030
    Location:19802089
    Creb_binding; Creb binding
    pfam09606
    Location:19482367
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cd15802
    Location:11611233
    RING_CBP-p300; atypical RING domain found in CREB-binding protein and p300 histone acetyltransferases
    cd15646
    Location:12341268
    PHD_p300; PHD finger found in histone acetyltransferase p300

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_133403.1: Suppressed sequence

    Description
    NM_133403.1: This RefSeq was suppressed temporarily based on the calculation that the annotated protein was shorter than a protein or proteins from a putative ortholog.